File Download
There are no files associated with this item.
Supplementary
-
Citations:
- Scopus: 0
- Appears in Collections:
Article: Successful treatment of X-linked lymphoproliferative disease (XLP) with anti-CD20 monoclonal antibody (Rituximab) followed by mismatched unrelated cord blood transplantation
Title | Successful treatment of X-linked lymphoproliferative disease (XLP) with anti-CD20 monoclonal antibody (Rituximab) followed by mismatched unrelated cord blood transplantation |
---|---|
Authors | |
Keywords | Anti-Cd20 Monoclonal Antibody Cord Blood Transplantation Rituximab X-Linked Lymphoproliferative Disease |
Issue Date | 2006 |
Publisher | Medcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp |
Citation | Hong Kong Journal Of Paediatrics, 2006, v. 11 n. 3, p. 210-214+264 How to Cite? |
Abstract | A 4-year-old boy with X-linked lymphoproliferative disease (XLP) developed life-threatening acute lymphoproliferative crisis and failed to respond to conventional treatment of dexamethasone and etoposide. With the knowledge that uncontrolled alloreactive cytotoxic T-cell responses triggered by EBV-transformed B cells is the main cause of XLP, anti-CD20 monoclonocal antibody (Rituximab) which directed against B lymphocytes was use to damp down the patient's dysregulated immune response. He responded well to this novel approach and entered into complete remission with this treatment. His inherited immuno-deficient genetic defect was subsequently corrected by unrelated cord blood transplantation. |
Persistent Identifier | http://hdl.handle.net/10722/170368 |
ISSN | 2023 Impact Factor: 0.1 2023 SCImago Journal Rankings: 0.117 |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, TL | en_US |
dc.contributor.author | Law, HKW | en_US |
dc.contributor.author | Chan, GCF | en_US |
dc.contributor.author | Ha, SY | en_US |
dc.contributor.author | Ho, MHK | en_US |
dc.contributor.author | Chan, KW | en_US |
dc.contributor.author | Lau, YL | en_US |
dc.date.accessioned | 2012-10-30T06:07:51Z | - |
dc.date.available | 2012-10-30T06:07:51Z | - |
dc.date.issued | 2006 | en_US |
dc.identifier.citation | Hong Kong Journal Of Paediatrics, 2006, v. 11 n. 3, p. 210-214+264 | en_US |
dc.identifier.issn | 1013-9923 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170368 | - |
dc.description.abstract | A 4-year-old boy with X-linked lymphoproliferative disease (XLP) developed life-threatening acute lymphoproliferative crisis and failed to respond to conventional treatment of dexamethasone and etoposide. With the knowledge that uncontrolled alloreactive cytotoxic T-cell responses triggered by EBV-transformed B cells is the main cause of XLP, anti-CD20 monoclonocal antibody (Rituximab) which directed against B lymphocytes was use to damp down the patient's dysregulated immune response. He responded well to this novel approach and entered into complete remission with this treatment. His inherited immuno-deficient genetic defect was subsequently corrected by unrelated cord blood transplantation. | en_US |
dc.language | eng | en_US |
dc.publisher | Medcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp | en_US |
dc.relation.ispartof | Hong Kong Journal of Paediatrics | en_US |
dc.subject | Anti-Cd20 Monoclonal Antibody | en_US |
dc.subject | Cord Blood Transplantation | en_US |
dc.subject | Rituximab | en_US |
dc.subject | X-Linked Lymphoproliferative Disease | en_US |
dc.title | Successful treatment of X-linked lymphoproliferative disease (XLP) with anti-CD20 monoclonal antibody (Rituximab) followed by mismatched unrelated cord blood transplantation | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chan, GCF:gcfchan@hkucc.hku.hk | en_US |
dc.identifier.email | Lau, YL:lauylung@hkucc.hku.hk | en_US |
dc.identifier.authority | Chan, GCF=rp00431 | en_US |
dc.identifier.authority | Lau, YL=rp00361 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-33746331029 | en_US |
dc.identifier.hkuros | 120575 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-33746331029&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 11 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.spage | 210 | en_US |
dc.identifier.epage | 214+264 | en_US |
dc.publisher.place | Hong Kong | en_US |
dc.identifier.scopusauthorid | Lee, TL=24483772800 | en_US |
dc.identifier.scopusauthorid | Law, HKW=7101939394 | en_US |
dc.identifier.scopusauthorid | Chan, GCF=16160154400 | en_US |
dc.identifier.scopusauthorid | Ha, SY=7202501115 | en_US |
dc.identifier.scopusauthorid | Ho, MHK=36554116300 | en_US |
dc.identifier.scopusauthorid | Chan, KW=8587755300 | en_US |
dc.identifier.scopusauthorid | Lau, YL=7201403380 | en_US |
dc.identifier.issnl | 1013-9923 | - |