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- Publisher Website: 10.1042/cs068s121
- Scopus: eid_2-s2.0-0021911566
- PMID: 2857606
- WOS: WOS:A1985ACE9200024
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Article: Modulation of postjunctional α-adrenergic responsiveness by local changes in temperature
Title | Modulation of postjunctional α-adrenergic responsiveness by local changes in temperature |
---|---|
Authors | |
Issue Date | 1985 |
Publisher | Portland Press Ltd. The Journal's web site is located at http://www.clinsci.org/ |
Citation | Clinical Science, 1985, v. 68 SUPPL. 10, p. 121S-123S How to Cite? |
Abstract | 1. In canine cutaneous veins, local moderate warming (37°-41°C) augments the responsiveness to postjunctional α1-adrenergic stimulation but depresses that to postjunctional α2-adrenergic activation. Moderate cooling (37° C-24°C) has the opposite effect. 2. The effects of warming and cooling on α1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in α2-adrenergic responsiveness. |
Persistent Identifier | http://hdl.handle.net/10722/170772 |
ISSN | 2023 Impact Factor: 6.7 2023 SCImago Journal Rankings: 1.565 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vanhoutte, PM | en_US |
dc.contributor.author | Cooke, JP | en_US |
dc.contributor.author | Lindblad, LE | en_US |
dc.date.accessioned | 2012-10-30T06:10:47Z | - |
dc.date.available | 2012-10-30T06:10:47Z | - |
dc.date.issued | 1985 | en_US |
dc.identifier.citation | Clinical Science, 1985, v. 68 SUPPL. 10, p. 121S-123S | en_US |
dc.identifier.issn | 0143-5221 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/170772 | - |
dc.description.abstract | 1. In canine cutaneous veins, local moderate warming (37°-41°C) augments the responsiveness to postjunctional α1-adrenergic stimulation but depresses that to postjunctional α2-adrenergic activation. Moderate cooling (37° C-24°C) has the opposite effect. 2. The effects of warming and cooling on α1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in α2-adrenergic responsiveness. | en_US |
dc.language | eng | en_US |
dc.publisher | Portland Press Ltd. The Journal's web site is located at http://www.clinsci.org/ | en_US |
dc.relation.ispartof | Clinical Science | en_US |
dc.subject.mesh | Adrenergic Alpha-Agonists - Pharmacology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Muscle Contraction - Drug Effects | en_US |
dc.subject.mesh | Neuromuscular Junction - Drug Effects | en_US |
dc.subject.mesh | Norepinephrine - Pharmacology | en_US |
dc.subject.mesh | Potassium - Pharmacology | en_US |
dc.subject.mesh | Receptors, Adrenergic, Alpha - Drug Effects - Physiology | en_US |
dc.subject.mesh | Saphenous Vein | en_US |
dc.subject.mesh | Synaptic Transmission - Drug Effects | en_US |
dc.subject.mesh | Temperature | en_US |
dc.title | Modulation of postjunctional α-adrenergic responsiveness by local changes in temperature | en_US |
dc.type | Article | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1042/cs068s121 | - |
dc.identifier.pmid | 2857606 | - |
dc.identifier.scopus | eid_2-s2.0-0021911566 | en_US |
dc.identifier.volume | 68 | en_US |
dc.identifier.issue | SUPPL. 10 | en_US |
dc.identifier.spage | 121S | en_US |
dc.identifier.epage | 123S | en_US |
dc.identifier.isi | WOS:A1985ACE9200024 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.scopusauthorid | Cooke, JP=7202378672 | en_US |
dc.identifier.scopusauthorid | Lindblad, LE=19735934700 | en_US |
dc.identifier.issnl | 0143-5221 | - |