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- Scopus: eid_2-s2.0-0023914356
- PMID: 3371471
- WOS: WOS:A1988N887400002
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Article: Cancer of the cervix stage Ib and IIa: Survival related to treatment and histopathological risk factors
Title | Cancer of the cervix stage Ib and IIa: Survival related to treatment and histopathological risk factors |
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Authors | |
Issue Date | 1988 |
Publisher | WB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejso |
Citation | European Journal Of Surgical Oncology, 1988, v. 14 n. 3, p. 203-208 How to Cite? |
Abstract | Forty-five patients with carcinoma of the cervix stage Ib or IIa underwent primary radical surgery. The patho-histological examination of the surgical specimens showed, that pelvic lymph node metastases, tumour volume, depth of tumour invasion, lymphatic or vascular permeation and parametrial involvement were significant bad prognostic factors. The histological types of squamous cell carcinomas and local lympho-plasmocytic stromal reaction to the tumour had no statistical prognostic significance. A simple and objective method of assessing tumour volume is described. The 5-year actuarial survival rate for patients with metastatic pelvic lymph nodes (33% of the patients in this study) treated by surgery and additional postoperative external whole pelvis radiotherapy was 55%. This is significantly lower than the 86% 5-year actuarial surivival rate of patients without pelvic lymph node metastases treated by surgery alone (P < 0.05). The postoperative radiotherapy of carcinoma of the cervix with bad prognostic factors including pelvic lymph node metastases seems to improve local tumour control and perhaps survival in a subgroup of node negative tumours presenting other histopathological risk factors. |
Persistent Identifier | http://hdl.handle.net/10722/173133 |
ISSN | 2023 Impact Factor: 3.5 2023 SCImago Journal Rankings: 1.164 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ngan, HYS | en_US |
dc.contributor.author | Obradovic, D | en_US |
dc.contributor.author | Krauer, F | en_US |
dc.date.accessioned | 2012-10-30T06:28:07Z | - |
dc.date.available | 2012-10-30T06:28:07Z | - |
dc.date.issued | 1988 | en_US |
dc.identifier.citation | European Journal Of Surgical Oncology, 1988, v. 14 n. 3, p. 203-208 | en_US |
dc.identifier.issn | 0748-7983 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173133 | - |
dc.description.abstract | Forty-five patients with carcinoma of the cervix stage Ib or IIa underwent primary radical surgery. The patho-histological examination of the surgical specimens showed, that pelvic lymph node metastases, tumour volume, depth of tumour invasion, lymphatic or vascular permeation and parametrial involvement were significant bad prognostic factors. The histological types of squamous cell carcinomas and local lympho-plasmocytic stromal reaction to the tumour had no statistical prognostic significance. A simple and objective method of assessing tumour volume is described. The 5-year actuarial survival rate for patients with metastatic pelvic lymph nodes (33% of the patients in this study) treated by surgery and additional postoperative external whole pelvis radiotherapy was 55%. This is significantly lower than the 86% 5-year actuarial surivival rate of patients without pelvic lymph node metastases treated by surgery alone (P < 0.05). The postoperative radiotherapy of carcinoma of the cervix with bad prognostic factors including pelvic lymph node metastases seems to improve local tumour control and perhaps survival in a subgroup of node negative tumours presenting other histopathological risk factors. | en_US |
dc.language | eng | en_US |
dc.publisher | WB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejso | en_US |
dc.relation.ispartof | European Journal of Surgical Oncology | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Combined Modality Therapy | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Lymphatic Metastasis | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Neoplasm Staging | en_US |
dc.subject.mesh | Prognosis | en_US |
dc.subject.mesh | Risk Factors | en_US |
dc.subject.mesh | Uterine Cervical Neoplasms - Mortality - Pathology - Therapy | en_US |
dc.title | Cancer of the cervix stage Ib and IIa: Survival related to treatment and histopathological risk factors | en_US |
dc.type | Article | en_US |
dc.identifier.email | Ngan, HYS:hysngan@hkucc.hku.hk | en_US |
dc.identifier.authority | Ngan, HYS=rp00346 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 3371471 | - |
dc.identifier.scopus | eid_2-s2.0-0023914356 | en_US |
dc.identifier.volume | 14 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.spage | 203 | en_US |
dc.identifier.epage | 208 | en_US |
dc.identifier.isi | WOS:A1988N887400002 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Ngan, HYS=34571944100 | en_US |
dc.identifier.scopusauthorid | Obradovic, D=7005065269 | en_US |
dc.identifier.scopusauthorid | Krauer, F=7004223818 | en_US |
dc.identifier.issnl | 0748-7983 | - |