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Article: Obesity, adipokines and cancer: an update

TitleObesity, adipokines and cancer: an update
Authors
Issue Date2014
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0300-0664
Citation
Clinical Endocrinology, 2014, v. 83 n. 2, p. 147–156 How to Cite?
AbstractObesity causes dysfunction of adipose tissue, with resultant chronic inflammation and adverse interplay of various adipokines, sex steroids and endocrine hormones. All these drive tumourigenesis and explain the epidemiological link between obesity and cancer. Over the past decade, the associations among obesity, adipokines and cancer have been increasingly recognized. Adipokines and their respective signalling pathways have drawn much research attention in the field of oncology and cancer therapeutics. This review will discuss the recent advances in the understanding of the association of several adipokines with common obesity-related cancers and the clinical therapeutic implications.
Persistent Identifierhttp://hdl.handle.net/10722/211506
ISSN
2021 Impact Factor: 3.523
2020 SCImago Journal Rankings: 1.055
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLee, CHP-
dc.contributor.authorWoo, YC-
dc.contributor.authorWang, Y-
dc.contributor.authorYeung, CY-
dc.contributor.authorXu, A-
dc.contributor.authorLam, KSL-
dc.date.accessioned2015-07-16T01:44:41Z-
dc.date.available2015-07-16T01:44:41Z-
dc.date.issued2014-
dc.identifier.citationClinical Endocrinology, 2014, v. 83 n. 2, p. 147–156-
dc.identifier.issn0300-0664-
dc.identifier.urihttp://hdl.handle.net/10722/211506-
dc.description.abstractObesity causes dysfunction of adipose tissue, with resultant chronic inflammation and adverse interplay of various adipokines, sex steroids and endocrine hormones. All these drive tumourigenesis and explain the epidemiological link between obesity and cancer. Over the past decade, the associations among obesity, adipokines and cancer have been increasingly recognized. Adipokines and their respective signalling pathways have drawn much research attention in the field of oncology and cancer therapeutics. This review will discuss the recent advances in the understanding of the association of several adipokines with common obesity-related cancers and the clinical therapeutic implications.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0300-0664-
dc.relation.ispartofClinical Endocrinology-
dc.rightsThis is the accepted version of the following article: Clinical Endocrinology, 2014, v. 83 n. 2, p. 147–156, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/cen.12667/abstract-
dc.titleObesity, adipokines and cancer: an update-
dc.typeArticle-
dc.identifier.emailLee, CHP: pchlee@hku.hk-
dc.identifier.emailWoo, YC: wooyucho@hku.hk-
dc.identifier.emailWang, Y: yuwanghk@hku.hk-
dc.identifier.emailYeung, CY: ycy167@hku.hk-
dc.identifier.emailXu, A: amxu@hkucc.hku.hk-
dc.identifier.emailLam, KSL: ksllam@hku.hk-
dc.identifier.authorityLee, CHP=rp02043-
dc.identifier.authorityWang, Y=rp00239-
dc.identifier.authorityXu, A=rp00485-
dc.identifier.authorityLam, KSL=rp00343-
dc.description.naturepostprint-
dc.identifier.doi10.1111/cen.12667-
dc.identifier.pmid25393563-
dc.identifier.scopuseid_2-s2.0-84937141032-
dc.identifier.hkuros244419-
dc.identifier.volume83-
dc.identifier.issue2-
dc.identifier.spage147-
dc.identifier.epage156-
dc.identifier.isiWOS:000358082500001-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl0300-0664-

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