File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1002/mabi.201400366
- Scopus: eid_2-s2.0-84927158407
- PMID: 25407891
- WOS: WOS:000352810800006
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Multiphase Protein Microgels
Title | Multiphase Protein Microgels |
---|---|
Authors | |
Keywords | aqueous two phase system dextran lysozyme microfluidics nanofibrillar protein microgel PEG |
Issue Date | 2015 |
Publisher | Wiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/vch/journals/2127/index.html |
Citation | Macromolecular Bioscience, 2015, v. 15 n. 4, p. 501-508 How to Cite? |
Abstract | Peptides and proteins represent attractive building blocks for the development of new functional materials due to the biocompatibility and biodegradability of many naturally abundant proteins. In nature, sophisticated material functionality is commonly achieved through spatial control of protein localisation and structure on both the nano and micro scales. We approached this requirement in an artificial setting by exploiting the propensity of proteins to self-assemble into amyloid fibrils to achieve nano scale order, and utilised aqueous liquid/liquid phase separation to control the micron scale localization of the proteinaceous component under microconfinement. We show that in combination with droplet microfluidics, this strategy allows the synthesis of core-shell microgel particles composed of protein nanofibrils. |
Persistent Identifier | http://hdl.handle.net/10722/218756 |
ISSN | 2021 Impact Factor: 5.859 2020 SCImago Journal Rankings: 0.924 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shimanovich, U | - |
dc.contributor.author | Song, Y | - |
dc.contributor.author | Brujic, J | - |
dc.contributor.author | Shum, HC | - |
dc.contributor.author | Knowles, TPJ | - |
dc.date.accessioned | 2015-09-18T06:52:32Z | - |
dc.date.available | 2015-09-18T06:52:32Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Macromolecular Bioscience, 2015, v. 15 n. 4, p. 501-508 | - |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | http://hdl.handle.net/10722/218756 | - |
dc.description.abstract | Peptides and proteins represent attractive building blocks for the development of new functional materials due to the biocompatibility and biodegradability of many naturally abundant proteins. In nature, sophisticated material functionality is commonly achieved through spatial control of protein localisation and structure on both the nano and micro scales. We approached this requirement in an artificial setting by exploiting the propensity of proteins to self-assemble into amyloid fibrils to achieve nano scale order, and utilised aqueous liquid/liquid phase separation to control the micron scale localization of the proteinaceous component under microconfinement. We show that in combination with droplet microfluidics, this strategy allows the synthesis of core-shell microgel particles composed of protein nanofibrils. | - |
dc.language | eng | - |
dc.publisher | Wiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www.wiley-vch.de/vch/journals/2127/index.html | - |
dc.relation.ispartof | Macromolecular Bioscience | - |
dc.subject | aqueous two phase system | - |
dc.subject | dextran | - |
dc.subject | lysozyme | - |
dc.subject | microfluidics | - |
dc.subject | nanofibrillar protein microgel | - |
dc.subject | PEG | - |
dc.title | Multiphase Protein Microgels | - |
dc.type | Article | - |
dc.identifier.email | Shum, HC: ashum@hku.hk | - |
dc.identifier.authority | Shum, HC=rp01439 | - |
dc.identifier.doi | 10.1002/mabi.201400366 | - |
dc.identifier.pmid | 25407891 | - |
dc.identifier.scopus | eid_2-s2.0-84927158407 | - |
dc.identifier.hkuros | 250685 | - |
dc.identifier.volume | 15 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 501 | - |
dc.identifier.epage | 508 | - |
dc.identifier.isi | WOS:000352810800006 | - |
dc.publisher.place | Germany | - |
dc.identifier.issnl | 1616-5187 | - |