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Article: Association of Oseltamivir Treatment With Virus Shedding, Illness, and Household Transmission of Influenza Viruses

TitleAssociation of Oseltamivir Treatment With Virus Shedding, Illness, and Household Transmission of Influenza Viruses
Authors
Cheung, DHTsang, TKFang, VJXu, JChan, KHIp, DKMPeiris, JSMLeung, GMCowling, BJ
KeywordsInfluenza
Oseltamivir
Acute respiratory illness
Issue Date2015
PublisherOxford University Press. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/jid/
Citation
Journal of Infectious Diseases, 2015, v. 212 n. 3, p. 391-396 How to Cite?
DOI: http://dx.doi.org/10.1093/infdis/jiv058
AbstractIn an observational study of 582 patients with laboratory-confirmed influenza virus infections and their household contacts, we found that the initiation of oseltamivir within 24 hours was associated with shorter duration of self-reported illness symptoms (56% reduction in duration; 95% confidence interval, 41%–67%). However, we did not find any association of oseltamivir treatment with duration of viral shedding by polymerase chain reaction or with the risk of household transmission.
Persistent Identifierhttp://hdl.handle.net/10722/220554
ISSN
0022-1899
2021 Impact Factor: 7.759
2020 SCImago Journal Rankings: 2.690
PubMed Central ID
PMC4866553
ISI Accession Number ID
WOS:000357824300008

 

DC FieldValueLanguage
dc.contributor.authorCheung, DH-
dc.contributor.authorTsang, TK-
dc.contributor.authorFang, VJ-
dc.contributor.authorXu, J-
dc.contributor.authorChan, KH-
dc.contributor.authorIp, DKM-
dc.contributor.authorPeiris, JSM-
dc.contributor.authorLeung, GM-
dc.contributor.authorCowling, BJ-
dc.date.accessioned2015-10-16T06:45:15Z-
dc.date.available2015-10-16T06:45:15Z-
dc.date.issued2015-
dc.identifier.citationJournal of Infectious Diseases, 2015, v. 212 n. 3, p. 391-396-
dc.identifier.issn0022-1899-
dc.identifier.urihttp://hdl.handle.net/10722/220554-
dc.description.abstractIn an observational study of 582 patients with laboratory-confirmed influenza virus infections and their household contacts, we found that the initiation of oseltamivir within 24 hours was associated with shorter duration of self-reported illness symptoms (56% reduction in duration; 95% confidence interval, 41%–67%). However, we did not find any association of oseltamivir treatment with duration of viral shedding by polymerase chain reaction or with the risk of household transmission.-
dc.languageeng-
dc.publisherOxford University Press. The Journal's web site is located at http://www.oxfordjournals.org/our_journals/jid/-
dc.relation.ispartofJournal of Infectious Diseases-
dc.subjectInfluenza-
dc.subjectOseltamivir-
dc.subjectAcute respiratory illness-
dc.titleAssociation of Oseltamivir Treatment With Virus Shedding, Illness, and Household Transmission of Influenza Viruses-
dc.typeArticle-
dc.identifier.emailTsang, TK: matklab@hku.hk-
dc.identifier.emailFang, VJ: vickyf@hku.hk-
dc.identifier.emailChan, KH: chankh2@hkucc.hku.hk-
dc.identifier.emailIp, DKM: dkmip@hku.hk-
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hk-
dc.identifier.emailLeung, GM: gmleung@hku.hk-
dc.identifier.emailCowling, BJ: bcowling@hku.hk-
dc.identifier.authorityTsang, TK=rp02571-
dc.identifier.authorityChan, KH=rp01921-
dc.identifier.authorityIp, DKM=rp00256-
dc.identifier.authorityPeiris, JSM=rp00410-
dc.identifier.authorityLeung, GM=rp00460-
dc.identifier.authorityCowling, BJ=rp01326-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1093/infdis/jiv058-
dc.identifier.pmid25646354-
dc.identifier.pmcidPMC4866553-
dc.identifier.scopuseid_2-s2.0-84939501950-
dc.identifier.hkuros255495-
dc.identifier.volume212-
dc.identifier.issue3-
dc.identifier.spage391-
dc.identifier.epage396-
dc.identifier.isiWOS:000357824300008-
dc.publisher.placeUnited States-
dc.identifier.issnl0022-1899-

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