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Conference Paper: Preventing root caries with SDF in fluoridated and non-fluoridated areas
Title | Preventing root caries with SDF in fluoridated and non-fluoridated areas |
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Authors | |
Issue Date | 2017 |
Publisher | International Association for Dental Research. The Abstracts' web site is located at http://www.iadr.org/IADR/Publications/JDR |
Citation | The 95th General Session and Exhibition of the International Association for Dental Research (IADR) held with the 46th Annual Meeting of the American Association for Dental Research (AADR) and the 41st Annual Meeting of the Canadian Association for Dental Research (CADR), San Francisco, CA., 22-25 March 2017, presentation no. IP-2991 How to Cite? |
Abstract | Objectives: To describe the effectiveness of annual application of silver diammine fluoride (SDF) solution in preventing root caries in community-dwelling elders living in fluoridated and non-fluoridated areas.
Methods: This was a 2-site randomized controlled trial conducted in Hong Kong (HK), an optimally water-fluoridated area, and in Guangzhou (GZ), non-fluoridated with a water fluoride concentration <0.2 ppm. Community-dwelling elders who were generally healthy and had at least 5 teeth with exposed root surfaces (not indicated for extraction) were recruited and randomly allocated into 2 groups: test – annual application of 38% SDF solution, and placebo control – annual application of tonic water. Individualized oral hygiene instructions and a toothpaste with 1000 ppm fluoride was provided to all subjects. Status of the tooth root surfaces were examined by calibrated examiners at baseline and thereafter every 6 months.
Results: A total of 533 elders (mean age = 68.6) were recruited at baseline, 260 in HK and 273 in GZ. After 24 months, 413 (77.5%) of these elders were examined, 208 in HK and 205 in GZ. The mean numbers of new root surface caries in the four groups were: 0.52±0.86 in GZ control, 0.46±0.82 in HK control, 0.32±0.68 in HK test, and 0.18±0.48 in GZ test (ANOVA, p=0.004). The pooled mean 24-month root caries increments in the subjects receiving SDF application and those receiving placebo were 0.25 and 0.49, respectively (t-test, p=0.001), giving a prevented fraction of 49%. Other studied possible confounding factors such as denture wearing and full-mouth plaque score did not have a statistically significant impact on the development of new root caries (ANCOVA, p>0.05), except baseline DMFT score (p<0.001).
Conclusions: Based on the 24-month results, it is concluded that annual topical application of 38% SDF solution can prevent root caries in community-dwelling elders in both water-fluoridated and non-fluoridated areas. |
Description | Oral Session: Cariology Clinical Studies- Effectiveness of SDF - presentation no. IP-2991 |
Persistent Identifier | http://hdl.handle.net/10722/248633 |
DC Field | Value | Language |
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dc.contributor.author | Lo, ECM | - |
dc.contributor.author | Li, R | - |
dc.contributor.author | Chu, CH | - |
dc.contributor.author | Lin, HC | - |
dc.date.accessioned | 2017-10-18T08:46:13Z | - |
dc.date.available | 2017-10-18T08:46:13Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | The 95th General Session and Exhibition of the International Association for Dental Research (IADR) held with the 46th Annual Meeting of the American Association for Dental Research (AADR) and the 41st Annual Meeting of the Canadian Association for Dental Research (CADR), San Francisco, CA., 22-25 March 2017, presentation no. IP-2991 | - |
dc.identifier.uri | http://hdl.handle.net/10722/248633 | - |
dc.description | Oral Session: Cariology Clinical Studies- Effectiveness of SDF - presentation no. IP-2991 | - |
dc.description.abstract | Objectives: To describe the effectiveness of annual application of silver diammine fluoride (SDF) solution in preventing root caries in community-dwelling elders living in fluoridated and non-fluoridated areas. Methods: This was a 2-site randomized controlled trial conducted in Hong Kong (HK), an optimally water-fluoridated area, and in Guangzhou (GZ), non-fluoridated with a water fluoride concentration <0.2 ppm. Community-dwelling elders who were generally healthy and had at least 5 teeth with exposed root surfaces (not indicated for extraction) were recruited and randomly allocated into 2 groups: test – annual application of 38% SDF solution, and placebo control – annual application of tonic water. Individualized oral hygiene instructions and a toothpaste with 1000 ppm fluoride was provided to all subjects. Status of the tooth root surfaces were examined by calibrated examiners at baseline and thereafter every 6 months. Results: A total of 533 elders (mean age = 68.6) were recruited at baseline, 260 in HK and 273 in GZ. After 24 months, 413 (77.5%) of these elders were examined, 208 in HK and 205 in GZ. The mean numbers of new root surface caries in the four groups were: 0.52±0.86 in GZ control, 0.46±0.82 in HK control, 0.32±0.68 in HK test, and 0.18±0.48 in GZ test (ANOVA, p=0.004). The pooled mean 24-month root caries increments in the subjects receiving SDF application and those receiving placebo were 0.25 and 0.49, respectively (t-test, p=0.001), giving a prevented fraction of 49%. Other studied possible confounding factors such as denture wearing and full-mouth plaque score did not have a statistically significant impact on the development of new root caries (ANCOVA, p>0.05), except baseline DMFT score (p<0.001). Conclusions: Based on the 24-month results, it is concluded that annual topical application of 38% SDF solution can prevent root caries in community-dwelling elders in both water-fluoridated and non-fluoridated areas. | - |
dc.language | eng | - |
dc.publisher | International Association for Dental Research. The Abstracts' web site is located at http://www.iadr.org/IADR/Publications/JDR | - |
dc.relation.ispartof | IADR/AADR/CADR 2017 General Session & Exhibition | - |
dc.title | Preventing root caries with SDF in fluoridated and non-fluoridated areas | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Lo, ECM: edward-lo@hku.hk | - |
dc.identifier.email | Chu, CH: chchu@hku.hk | - |
dc.identifier.authority | Lo, ECM=rp00015 | - |
dc.identifier.authority | Chu, CH=rp00022 | - |
dc.identifier.hkuros | 280876 | - |
dc.publisher.place | United States | - |