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Article: IL-36 cytokines in autoimmunity and inflammatory disease

TitleIL-36 cytokines in autoimmunity and inflammatory disease
Authors
Ding, LWang, XHong, XLu, LLiu, D
KeywordsInterleukin-36
Inflammatory disease
Psoriasis
Arthritis
Issue Date2018
PublisherImpact Journals LLC. The Journal's web site is located at http://www.impactjournals.com/oncotarget/index.html
Citation
Oncotarget, 2018, v. 9 n. 2, p. 2895-2901 How to Cite?
DOI: http://dx.doi.org/10.18632/oncotarget.22814
AbstractThe inteleukin-36 (IL-36) cytokines include IL-36α, IL-36β, IL-36γ and IL-36Ra, which belong to the IL-1 family and exert pro-inflammatory effects on various target cells such as keratinocytes, synoviocytes, dendritic cells and T cells. Emerging evidence has suggested a role of IL-36 in the pathogenesis of many inflammatory diseases. Here, we provide a brief review on the activation of IL-36 family cytokines and their involvement in autoimmunity and inflammatory diseases, which will provide further insights in understanding the functions of IL-36 family cytokines in the pathophysiology of autoimmunity and inflammatory diseases.
Persistent Identifierhttp://hdl.handle.net/10722/261928
ISSN
1949-2553
2016 Impact Factor: 5.168
2020 SCImago Journal Rankings: 1.373
PubMed Central ID
PMC5788690
ISI Accession Number ID
WOS:000419623200115

 

DC FieldValueLanguage
dc.contributor.authorDing, L-
dc.contributor.authorWang, X-
dc.contributor.authorHong, X-
dc.contributor.authorLu, L-
dc.contributor.authorLiu, D-
dc.date.accessioned2018-09-28T04:50:29Z-
dc.date.available2018-09-28T04:50:29Z-
dc.date.issued2018-
dc.identifier.citationOncotarget, 2018, v. 9 n. 2, p. 2895-2901-
dc.identifier.issn1949-2553-
dc.identifier.urihttp://hdl.handle.net/10722/261928-
dc.description.abstractThe inteleukin-36 (IL-36) cytokines include IL-36α, IL-36β, IL-36γ and IL-36Ra, which belong to the IL-1 family and exert pro-inflammatory effects on various target cells such as keratinocytes, synoviocytes, dendritic cells and T cells. Emerging evidence has suggested a role of IL-36 in the pathogenesis of many inflammatory diseases. Here, we provide a brief review on the activation of IL-36 family cytokines and their involvement in autoimmunity and inflammatory diseases, which will provide further insights in understanding the functions of IL-36 family cytokines in the pathophysiology of autoimmunity and inflammatory diseases.-
dc.languageeng-
dc.publisherImpact Journals LLC. The Journal's web site is located at http://www.impactjournals.com/oncotarget/index.html-
dc.relation.ispartofOncotarget-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectInterleukin-36-
dc.subjectInflammatory disease-
dc.subjectPsoriasis-
dc.subjectArthritis-
dc.titleIL-36 cytokines in autoimmunity and inflammatory disease-
dc.typeArticle-
dc.identifier.emailWang, X: xhwangxh@hku.hk-
dc.identifier.emailLu, L: liweilu@hku.hk-
dc.identifier.authorityWang, X=rp02664-
dc.identifier.authorityLu, L=rp00477-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.18632/oncotarget.22814-
dc.identifier.pmid29416822-
dc.identifier.pmcidPMC5788690-
dc.identifier.scopuseid_2-s2.0-85039979465-
dc.identifier.hkuros292461-
dc.identifier.volume9-
dc.identifier.issue2-
dc.identifier.spage2895-
dc.identifier.epage2901-
dc.identifier.isiWOS:000419623200115-
dc.publisher.placeUnited States-
dc.identifier.issnl1949-2553-

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