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Conference Paper: Management of malignant ureteric obstruction in patients with gastric cancer: survival outcomes from a 10-year experience

TitleManagement of malignant ureteric obstruction in patients with gastric cancer: survival outcomes from a 10-year experience
Authors
Issue Date2019
PublisherWiley-Blackwell Publishing Ltd. The Publication's web site is located at https://doi.org/10.1111/bju.14677
Citation
The 23rd Hong Kong Urological Assoication Annual Scientific Meeting, Hong Kong, 4 November 2018. In BJU International, 2019, v. 123 n. S1, p. 11, abstract no. OP.4‐6 How to Cite?
AbstractObjective: To compare survival outcomes between different treatment options of malignant ureteric obstruction secondary to gastric cancer. Patients and Methods: Cases of hydronephrosis secondary to gastric cancer from Jan 2006 to Dec 2016 in Queen Mary Hospital were retrospectively analysed. Drainage methods including ureteric stent, PCN, and conservative management were compared. Primary outcomes include disease‐specific and overall survival rates. Secondary outcomes include treatment failure rate and subsequent systemic therapy usage. Results: 52 cases in 32 patients were identified. The median survival after diagnosis of hydronephrosis was 4 months. Ureteric stent and PCN had no significant difference in disease‐specific (p = 0.143) and overall survival (p = 0.143). Ureteric stent had, however, significantly higher failure rate than PCN (44.4% vs 13.3%, p = 0.040). Ureteric stent and PCN had no difference in systemic therapy use (p = 0.890). Drainage of hydronephrosis had a higher trend of systemic therapy use than conservative treatment (45.2% vs 20.0%), but statistical significance could not be reached (p = 0.144). Drainage did not lead to better disease‐specific (p = 0.373) and overall survival (p = 0.822) when comparing with conservative treatment. Conclusion: There was no significant difference in survival outcomes between different treatment options. Decision for drainage should take into account patients’ symptoms and quality of life following the treatment options.
DescriptionOral Presentation - no. OP.4‐6
Persistent Identifierhttp://hdl.handle.net/10722/266486
ISSN
2017 Impact Factor: 4.688
2015 SCImago Journal Rankings: 2.009

 

DC FieldValueLanguage
dc.contributor.authorNg, YK-
dc.contributor.authorLai, TCT-
dc.contributor.authorTsang, CF-
dc.contributor.authorLam, PW-
dc.contributor.authorHo, SHB-
dc.contributor.authorNg, ATL-
dc.contributor.authorMa, WK-
dc.contributor.authorTsu, HLJ-
dc.date.accessioned2019-01-18T08:20:35Z-
dc.date.available2019-01-18T08:20:35Z-
dc.date.issued2019-
dc.identifier.citationThe 23rd Hong Kong Urological Assoication Annual Scientific Meeting, Hong Kong, 4 November 2018. In BJU International, 2019, v. 123 n. S1, p. 11, abstract no. OP.4‐6-
dc.identifier.issn1464-4096-
dc.identifier.urihttp://hdl.handle.net/10722/266486-
dc.descriptionOral Presentation - no. OP.4‐6-
dc.description.abstractObjective: To compare survival outcomes between different treatment options of malignant ureteric obstruction secondary to gastric cancer. Patients and Methods: Cases of hydronephrosis secondary to gastric cancer from Jan 2006 to Dec 2016 in Queen Mary Hospital were retrospectively analysed. Drainage methods including ureteric stent, PCN, and conservative management were compared. Primary outcomes include disease‐specific and overall survival rates. Secondary outcomes include treatment failure rate and subsequent systemic therapy usage. Results: 52 cases in 32 patients were identified. The median survival after diagnosis of hydronephrosis was 4 months. Ureteric stent and PCN had no significant difference in disease‐specific (p = 0.143) and overall survival (p = 0.143). Ureteric stent had, however, significantly higher failure rate than PCN (44.4% vs 13.3%, p = 0.040). Ureteric stent and PCN had no difference in systemic therapy use (p = 0.890). Drainage of hydronephrosis had a higher trend of systemic therapy use than conservative treatment (45.2% vs 20.0%), but statistical significance could not be reached (p = 0.144). Drainage did not lead to better disease‐specific (p = 0.373) and overall survival (p = 0.822) when comparing with conservative treatment. Conclusion: There was no significant difference in survival outcomes between different treatment options. Decision for drainage should take into account patients’ symptoms and quality of life following the treatment options.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Ltd. The Publication's web site is located at https://doi.org/10.1111/bju.14677-
dc.relation.ispartofBJU International-
dc.titleManagement of malignant ureteric obstruction in patients with gastric cancer: survival outcomes from a 10-year experience-
dc.typeConference_Paper-
dc.identifier.emailLam, PW: lamwayne@hku.hk-
dc.identifier.emailHo, SHB: hobrian@hku.hk-
dc.identifier.emailNg, ATL: ada5022@hku.hk-
dc.identifier.emailMa, WK: mwk054@hku.hk-
dc.identifier.emailTsu, HLJ: jamestsu@hku.hk-
dc.identifier.authorityLam, PW=rp02305-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros296743-
dc.identifier.volume123-
dc.identifier.issueS1-
dc.identifier.spage11-
dc.identifier.epage11-
dc.publisher.placeUnited Kingdom-

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