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Conference Paper: Is severe periodontitis a pre-indicator of abnormal systemic conditions?
Title | Is severe periodontitis a pre-indicator of abnormal systemic conditions? |
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Authors | |
Issue Date | 2019 |
Publisher | International Association for Dental Research. The Journal's web site is located at http://www.iadr.org/ |
Citation | The 97th General Session of the International Association of Dental Research (IADR) held with the 48th Annual Meeting of the American Association for Dental Research (AADR) & the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Vancouver, BC, Canada, 19-22 June 2019. In Journal of Dental Research, 2019, v. 98 n. Spec Iss A, abstract no. 0361 How to Cite? |
Abstract | Objectives: Our recent retrospective study provides the first evidence that periodontal status reflects overall host susceptibility to onset of systemic diseases/disorders, and herein we further investigated whether periodontitis occurrence could represent the current systemic abnormality.
Methods: Totally, 938 dental hospital attendees (35-75 yrs) completed a questionnaire on demographic characteristics, medical history, and health awareness. Of them, 205 ‘self-claimed generally healthy’ subjects received further periodontal assessment, and they were then classified as ‘Severe Periodontitis’ (generalized Stages 3-4, AAP/EFP 2017) and ‘Non-Severe Periodontitis’ groups. 50 pairs (36 females and 14 males) were included in the study with matched age, gender, and tobacco use. 17 medical diagnostic tests/parameters (e.g., cardiovascular disease, diabetes, dyslipidemia, hyperuricemia, and kidney dysfunction) were undertaken, and their mental/emotional conditions were evaluated.
Results: The mean age of the ‘Severe Periodontitis’ and ‘Non-Severe Periodontitis’ groups was 56.1±9.3 and 56.0±9.4 yrs, respectively. Tobacco use was compatible in both groups (8 pairs with comparable pack-years). Moreover, they had similar covariate profiles, including income and education levels, lifestyles (e.g., physical exercise frequency, sleep quality and assumption of sweets and alcohol), oral hygiene behaviors, mental state, and emotional conditions. Overall, 98 subjects exhibited at least one abnormal testing result. The prevalence of elevated systolic pressure and increased arterial stiffness was significantly higher in the subjects with severe periodontitis, as compared with their counterparts (76.0% vs 56.0% and 44.0% vs 24.0%, respectively; P < 0.05). Notably, a greater number of severe periodontitis patients presented ≥6 abnormal testing results than the controls (66% vs 42%, P =0.016), and the diagnostic abnormality (≥6 positively tested) was independently associated with generalized Stages 3-4 periodontitis (OR 3.44, P =0.016).
Conclusions: This pioneering study suggests that severe periodontitis may be a pre-indicator of existing abnormal systemic conditions, and proactive professional education/care are crucial for promoting oral health and general wellbeing. |
Description | Oral Session: Gum Health, Periodontitis, Quality of Life and Systemic Conditions - Final Presentation ID: 0361 |
Persistent Identifier | http://hdl.handle.net/10722/273438 |
DC Field | Value | Language |
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dc.contributor.author | Zhao, D | - |
dc.contributor.author | Yiu, KH | - |
dc.contributor.author | Wu, M | - |
dc.contributor.author | Yu, SY | - |
dc.contributor.author | Pelekos, G | - |
dc.contributor.author | Jin, L | - |
dc.date.accessioned | 2019-08-06T09:28:57Z | - |
dc.date.available | 2019-08-06T09:28:57Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | The 97th General Session of the International Association of Dental Research (IADR) held with the 48th Annual Meeting of the American Association for Dental Research (AADR) & the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Vancouver, BC, Canada, 19-22 June 2019. In Journal of Dental Research, 2019, v. 98 n. Spec Iss A, abstract no. 0361 | - |
dc.identifier.uri | http://hdl.handle.net/10722/273438 | - |
dc.description | Oral Session: Gum Health, Periodontitis, Quality of Life and Systemic Conditions - Final Presentation ID: 0361 | - |
dc.description.abstract | Objectives: Our recent retrospective study provides the first evidence that periodontal status reflects overall host susceptibility to onset of systemic diseases/disorders, and herein we further investigated whether periodontitis occurrence could represent the current systemic abnormality. Methods: Totally, 938 dental hospital attendees (35-75 yrs) completed a questionnaire on demographic characteristics, medical history, and health awareness. Of them, 205 ‘self-claimed generally healthy’ subjects received further periodontal assessment, and they were then classified as ‘Severe Periodontitis’ (generalized Stages 3-4, AAP/EFP 2017) and ‘Non-Severe Periodontitis’ groups. 50 pairs (36 females and 14 males) were included in the study with matched age, gender, and tobacco use. 17 medical diagnostic tests/parameters (e.g., cardiovascular disease, diabetes, dyslipidemia, hyperuricemia, and kidney dysfunction) were undertaken, and their mental/emotional conditions were evaluated. Results: The mean age of the ‘Severe Periodontitis’ and ‘Non-Severe Periodontitis’ groups was 56.1±9.3 and 56.0±9.4 yrs, respectively. Tobacco use was compatible in both groups (8 pairs with comparable pack-years). Moreover, they had similar covariate profiles, including income and education levels, lifestyles (e.g., physical exercise frequency, sleep quality and assumption of sweets and alcohol), oral hygiene behaviors, mental state, and emotional conditions. Overall, 98 subjects exhibited at least one abnormal testing result. The prevalence of elevated systolic pressure and increased arterial stiffness was significantly higher in the subjects with severe periodontitis, as compared with their counterparts (76.0% vs 56.0% and 44.0% vs 24.0%, respectively; P < 0.05). Notably, a greater number of severe periodontitis patients presented ≥6 abnormal testing results than the controls (66% vs 42%, P =0.016), and the diagnostic abnormality (≥6 positively tested) was independently associated with generalized Stages 3-4 periodontitis (OR 3.44, P =0.016). Conclusions: This pioneering study suggests that severe periodontitis may be a pre-indicator of existing abnormal systemic conditions, and proactive professional education/care are crucial for promoting oral health and general wellbeing. | - |
dc.language | eng | - |
dc.publisher | International Association for Dental Research. The Journal's web site is located at http://www.iadr.org/ | - |
dc.relation.ispartof | Journal of Dental Research (Spec Issue) | - |
dc.relation.ispartof | IADR/AADR/CADR 2019 General Session & Exhibition | - |
dc.title | Is severe periodontitis a pre-indicator of abnormal systemic conditions? | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Yiu, KH: khkyiu@hku.hk | - |
dc.identifier.email | Wu, M: wmz513@hku.hk | - |
dc.identifier.email | Yu, SY: angelysy@hku.hk | - |
dc.identifier.email | Pelekos, G: george74@hku.hk | - |
dc.identifier.email | Jin, L: ljjin@hkucc.hku.hk | - |
dc.identifier.authority | Yiu, KH=rp01490 | - |
dc.identifier.authority | Pelekos, G=rp01894 | - |
dc.identifier.authority | Jin, L=rp00028 | - |
dc.identifier.hkuros | 299759 | - |
dc.identifier.volume | 98 | - |
dc.identifier.issue | Spec Iss A | - |
dc.identifier.spage | abstract no. 0361 | - |
dc.identifier.epage | abstract no. 0361 | - |
dc.publisher.place | United States | - |