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Article: Bicomponent nanofibrous scaffolds with dual release of anticancer drugs and biomacromolecules
Title | Bicomponent nanofibrous scaffolds with dual release of anticancer drugs and biomacromolecules |
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Authors | |
Keywords | Diseases Emulsification Nanofibers Targeted drug delivery |
Issue Date | 2019 |
Publisher | Cambridge University Press. The Journal's web site is located at https://www.cambridge.org/core/journals/mrs-communications |
Citation | MRS Communications, 2019, v. 9 n. 1, p. 413-420 How to Cite? |
Abstract | Multifunctional scaffolds with dual release of small molecular drugs and biomacromolecules have potential in many applications such as cancer postoperative care, which require appropriate administration of anticancer drugs and biomacromolecules in a spatiotemporal manner. Herein, a systematic investigation into the dual release of anticancer drugs and biomacromolecules from the bicomponent nanofibrous scaffolds is performed. Their release behavior is affected by different fabrication techniques and different polymers used. We show that the bicomponent scaffold fabricated by dual-source dual-power emulsion electrospinning enables dual release of anticancer drugs and biomacromolecules in a controlled manner, holding promise for combinational cancer postoperative care. |
Persistent Identifier | http://hdl.handle.net/10722/277349 |
ISSN | 2023 Impact Factor: 1.8 2023 SCImago Journal Rankings: 0.390 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | ZHOU, Y | - |
dc.contributor.author | Zhao, Q | - |
dc.contributor.author | Tsai, NLY | - |
dc.contributor.author | Wang, M | - |
dc.date.accessioned | 2019-09-20T08:49:17Z | - |
dc.date.available | 2019-09-20T08:49:17Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | MRS Communications, 2019, v. 9 n. 1, p. 413-420 | - |
dc.identifier.issn | 2159-6859 | - |
dc.identifier.uri | http://hdl.handle.net/10722/277349 | - |
dc.description.abstract | Multifunctional scaffolds with dual release of small molecular drugs and biomacromolecules have potential in many applications such as cancer postoperative care, which require appropriate administration of anticancer drugs and biomacromolecules in a spatiotemporal manner. Herein, a systematic investigation into the dual release of anticancer drugs and biomacromolecules from the bicomponent nanofibrous scaffolds is performed. Their release behavior is affected by different fabrication techniques and different polymers used. We show that the bicomponent scaffold fabricated by dual-source dual-power emulsion electrospinning enables dual release of anticancer drugs and biomacromolecules in a controlled manner, holding promise for combinational cancer postoperative care. | - |
dc.language | eng | - |
dc.publisher | Cambridge University Press. The Journal's web site is located at https://www.cambridge.org/core/journals/mrs-communications | - |
dc.relation.ispartof | MRS Communications | - |
dc.rights | MRS Communications. Copyright © Cambridge University Press. | - |
dc.rights | This article has been published in a revised form in [Journal] [http://doi.org/XXX]. This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © copyright holder. | - |
dc.subject | Diseases | - |
dc.subject | Emulsification | - |
dc.subject | Nanofibers | - |
dc.subject | Targeted drug delivery | - |
dc.title | Bicomponent nanofibrous scaffolds with dual release of anticancer drugs and biomacromolecules | - |
dc.type | Article | - |
dc.identifier.email | Wang, M: memwang@hku.hk | - |
dc.identifier.authority | Wang, M=rp00185 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1557/mrc.2019.23 | - |
dc.identifier.scopus | eid_2-s2.0-85062492898 | - |
dc.identifier.hkuros | 306017 | - |
dc.identifier.volume | 9 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 413 | - |
dc.identifier.epage | 420 | - |
dc.identifier.isi | WOS:000462656200056 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 2159-6867 | - |