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Article: The efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis

TitleThe efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis
Authors
KeywordsStable angina pectoris
symptom management
complementary and alternative medicine
acupuncture
patient-centered outcomes
Issue Date2019
PublisherSage Publications Ltd. The Journal's web site is located at http://www.uk.sagepub.com/journals/Journal202014?siteId=sage-uk&prodTypes=any&q=European+Journal+of+Preventive+Cardiology+&fs=1
Citation
European Journal of Preventive Cardiology, 2019 How to Cite?
AbstractObjective The aim of this study was to assess the efficacy and safety of acupuncture in the treatment of patients with stable angina pectoris. Methods A literature search was performed in nine databases, including PubMed and the Cochrane Library, from their inception to 30 August 2018. Randomized controlled trials that compared acupuncture therapy with sham acupuncture or no treatment were included. Two reviewers under the guidance of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines assessed the eligibility of each record and extracted essential information independently. The data were merged using a fixed-effect model. Results Pooled analysis of 17 eligible trials with 1516 participants showed that acupuncture was associated with reduced angina attack frequency (–4.91; 95% confidence interval, –6.01– –3.82; p < 0.00001) and improved depression (–1.23; 95% confidence interval, –1.47– –1.00; p < 0.00001) and anxiety level (–0.96; 95% confidence interval, –1.16– –0.75; p < 0.00001) relative to sham treatment or standard care alone. No increased risk of adverse events was observed during treatment (relative risk, 0.70; 95% confidence interval, 0.33–1.48; p = 0.35). No significant improvement was shown in nitroglycerin use or angina intensity. The included studies were associated with unclear to high risk of selection or performance bias, and the quality of evidence was low to moderate. Conclusions Acupuncture may safely and effectively improve physical restrictions, emotional distress, and attack frequency in patients with stable angina pectoris. However, angina intensity and medication use were not reduced. Studies with adequate blinding and a valid sham control group are still warranted due to the current low quality of evidence.
Persistent Identifierhttp://hdl.handle.net/10722/278379
ISSN
2017 Impact Factor: 4.542
2015 SCImago Journal Rankings: 1.650

 

DC FieldValueLanguage
dc.contributor.authorYang, C-
dc.contributor.authorSun, M-
dc.contributor.authorDu, T-
dc.contributor.authorLong, H-
dc.contributor.authorChen, J-
dc.contributor.authorLiang, F-
dc.contributor.authorLao, L-
dc.date.accessioned2019-10-04T08:12:53Z-
dc.date.available2019-10-04T08:12:53Z-
dc.date.issued2019-
dc.identifier.citationEuropean Journal of Preventive Cardiology, 2019-
dc.identifier.issn2047-4873-
dc.identifier.urihttp://hdl.handle.net/10722/278379-
dc.description.abstractObjective The aim of this study was to assess the efficacy and safety of acupuncture in the treatment of patients with stable angina pectoris. Methods A literature search was performed in nine databases, including PubMed and the Cochrane Library, from their inception to 30 August 2018. Randomized controlled trials that compared acupuncture therapy with sham acupuncture or no treatment were included. Two reviewers under the guidance of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines assessed the eligibility of each record and extracted essential information independently. The data were merged using a fixed-effect model. Results Pooled analysis of 17 eligible trials with 1516 participants showed that acupuncture was associated with reduced angina attack frequency (–4.91; 95% confidence interval, –6.01– –3.82; p < 0.00001) and improved depression (–1.23; 95% confidence interval, –1.47– –1.00; p < 0.00001) and anxiety level (–0.96; 95% confidence interval, –1.16– –0.75; p < 0.00001) relative to sham treatment or standard care alone. No increased risk of adverse events was observed during treatment (relative risk, 0.70; 95% confidence interval, 0.33–1.48; p = 0.35). No significant improvement was shown in nitroglycerin use or angina intensity. The included studies were associated with unclear to high risk of selection or performance bias, and the quality of evidence was low to moderate. Conclusions Acupuncture may safely and effectively improve physical restrictions, emotional distress, and attack frequency in patients with stable angina pectoris. However, angina intensity and medication use were not reduced. Studies with adequate blinding and a valid sham control group are still warranted due to the current low quality of evidence.-
dc.languageeng-
dc.publisherSage Publications Ltd. The Journal's web site is located at http://www.uk.sagepub.com/journals/Journal202014?siteId=sage-uk&prodTypes=any&q=European+Journal+of+Preventive+Cardiology+&fs=1-
dc.relation.ispartofEuropean Journal of Preventive Cardiology-
dc.rightsEuropean Journal of Preventive Cardiology. Copyright © Sage Publications Ltd.-
dc.subjectStable angina pectoris-
dc.subjectsymptom management-
dc.subjectcomplementary and alternative medicine-
dc.subjectacupuncture-
dc.subjectpatient-centered outcomes-
dc.titleThe efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis-
dc.typeArticle-
dc.identifier.emailYang, C: mxyang@hku.hk-
dc.identifier.emailLao, L: lxlao1@hku.hk-
dc.identifier.authorityLao, L=rp01784-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1177/2047487319876761-
dc.identifier.hkuros306364-
dc.identifier.hkuros305238-
dc.identifier.spage204748731987676-
dc.identifier.epage204748731987676-
dc.publisher.placeUnited Kingdom-

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