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- Publisher Website: 10.1007/BF03017932
- Scopus: eid_2-s2.0-0036017679
- PMID: 11983670
- WOS: WOS:000175508400017
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Article: Co-adminstration of alfentanil-propofol improves laryngeal mask airway insertion compared to fentanyl-propofol
Title | Co-adminstration of alfentanil-propofol improves laryngeal mask airway insertion compared to fentanyl-propofol |
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Authors | |
Issue Date | 2002 |
Citation | Canadian Journal of Anesthesia, 2002, v. 49, n. 5, p. 508-512 How to Cite? |
Abstract | Purpose: Insertion of the laryngeal mask airway (LMA) requires sufficient depth of anesthesia to relax the jaw and obtund airway reflexes. Recent studies suggest that the short-acting opioid alfentanil provides the best insertion conditions. We therefore compared the insertion conditions following co-administration of alfentanil-propofol with more commonly used fentanyl-propofol. Methods: One hundred forty ASA I or II patients, age 18-81 yr, requiring minor surgery were recruited. They were randomized to receive either alfentanil (10 μg·kg-1; n = 73) or fentanyl (1 μg·kg-1; n = 67) with propofol (2.5 mg·kg-1) 90 sec prior to LMA (size 3 or 4) insertion. A six variable (mouth opening, ease of insertion, swallowing, coughing, movement and laryngospasm) three-point (nil / partial / total) score was used to assess insertion conditions. Duration of postinsertion apnea was recorded. Insertion conditions were compared using Chi-square for trends. Results: The two groups were demographically similar. Mouth opening and ease of insertion were not improved with alfentanil co-administration. Alfentanil-propofol reduced the incidence of swallowing, gagging, movement and laryngospasm (P < 0.05), with 29% (alfentanil) compared to 45% (fentanyl) of patients responding (P = 0.05) to LMA insertion. Apnea [mean (SD)] following alfentanil lasted 154 (139) sec compared to 82 (61) sec following fentanyl (P = 0.001). Conclusion: Co-administration of alfentanil-propofol provided better insertion conditions than fentanyl-propofol, though apnea was prolonged by 72 sec. |
Persistent Identifier | http://hdl.handle.net/10722/280512 |
ISSN | 2023 Impact Factor: 3.4 2023 SCImago Journal Rankings: 0.924 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Hui, Jacqueline K.L. | - |
dc.contributor.author | Critchley, Lester A.H. | - |
dc.contributor.author | Karmakar, Manoj K. | - |
dc.contributor.author | Lam, Patrick K.K. | - |
dc.date.accessioned | 2020-02-17T14:34:13Z | - |
dc.date.available | 2020-02-17T14:34:13Z | - |
dc.date.issued | 2002 | - |
dc.identifier.citation | Canadian Journal of Anesthesia, 2002, v. 49, n. 5, p. 508-512 | - |
dc.identifier.issn | 0832-610X | - |
dc.identifier.uri | http://hdl.handle.net/10722/280512 | - |
dc.description.abstract | Purpose: Insertion of the laryngeal mask airway (LMA) requires sufficient depth of anesthesia to relax the jaw and obtund airway reflexes. Recent studies suggest that the short-acting opioid alfentanil provides the best insertion conditions. We therefore compared the insertion conditions following co-administration of alfentanil-propofol with more commonly used fentanyl-propofol. Methods: One hundred forty ASA I or II patients, age 18-81 yr, requiring minor surgery were recruited. They were randomized to receive either alfentanil (10 μg·kg-1; n = 73) or fentanyl (1 μg·kg-1; n = 67) with propofol (2.5 mg·kg-1) 90 sec prior to LMA (size 3 or 4) insertion. A six variable (mouth opening, ease of insertion, swallowing, coughing, movement and laryngospasm) three-point (nil / partial / total) score was used to assess insertion conditions. Duration of postinsertion apnea was recorded. Insertion conditions were compared using Chi-square for trends. Results: The two groups were demographically similar. Mouth opening and ease of insertion were not improved with alfentanil co-administration. Alfentanil-propofol reduced the incidence of swallowing, gagging, movement and laryngospasm (P < 0.05), with 29% (alfentanil) compared to 45% (fentanyl) of patients responding (P = 0.05) to LMA insertion. Apnea [mean (SD)] following alfentanil lasted 154 (139) sec compared to 82 (61) sec following fentanyl (P = 0.001). Conclusion: Co-administration of alfentanil-propofol provided better insertion conditions than fentanyl-propofol, though apnea was prolonged by 72 sec. | - |
dc.language | eng | - |
dc.relation.ispartof | Canadian Journal of Anesthesia | - |
dc.title | Co-adminstration of alfentanil-propofol improves laryngeal mask airway insertion compared to fentanyl-propofol | - |
dc.type | Article | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1007/BF03017932 | - |
dc.identifier.pmid | 11983670 | - |
dc.identifier.scopus | eid_2-s2.0-0036017679 | - |
dc.identifier.volume | 49 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 508 | - |
dc.identifier.epage | 512 | - |
dc.identifier.isi | WOS:000175508400017 | - |
dc.identifier.issnl | 0832-610X | - |