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- Publisher Website: 10.1111/j.1365-2044.2011.06790.x
- Scopus: eid_2-s2.0-80051787049
- PMID: 21707564
- WOS: WOS:000293794800008
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Article: A double-blind randomised comparison of intravenous patient-controlled remifentanil with intramuscular pethidine for labour analgesia
Title | A double-blind randomised comparison of intravenous patient-controlled remifentanil with intramuscular pethidine for labour analgesia |
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Authors | |
Issue Date | 2011 |
Citation | Anaesthesia, 2011, v. 66, n. 9, p. 796-801 How to Cite? |
Abstract | In a prospective, double-blind, randomised controlled trial, we compared the efficacy of patient-controlled analgesia using remifentanil (25-30 μg per bolus) with intramuscular pethidine (50-75 mg) for labour analgesia in 69 parturients. Parturients receiving patient-controlled analgesia reported less pain than those receiving intramuscular pethidine throughout the study period (p < 0.001), with maximal reduction in visual analogue pain score at 2 h after commencement of analgesia (mean (SD) 20 (17) in the patient-controlled analgesia group and 36 (22) in the intramuscular pethidine group. The median (95% CI) time to the first request for rescue analgesics was significantly longer with patient-controlled analgesia (8.0 (6.8-9.2) h) compared with intramuscular pethidine (4.9 (3.8-5.4) h, p < 0.001). Maternal satisfaction scores were also higher with remifentanil compared with intramuscular pethidine (p= 0.001). There was no report of sedation, aponea or oxygen desaturation in either group, and Apgar scores were similar between groups. We conclude that patient-controlled analgesia with remifentanil provides better labour analgesia and maternal satisfaction than intramuscular pethidine. At this dose, maternal and fetal side effects were uncommon. © 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland. |
Persistent Identifier | http://hdl.handle.net/10722/280541 |
ISSN | 2023 Impact Factor: 7.5 2023 SCImago Journal Rankings: 2.400 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ng, T. K.T. | - |
dc.contributor.author | Cheng, B. C.P. | - |
dc.contributor.author | Chan, W. S. | - |
dc.contributor.author | Lam, K. K. | - |
dc.contributor.author | Chan, M. T.V. | - |
dc.date.accessioned | 2020-02-17T14:34:18Z | - |
dc.date.available | 2020-02-17T14:34:18Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Anaesthesia, 2011, v. 66, n. 9, p. 796-801 | - |
dc.identifier.issn | 0003-2409 | - |
dc.identifier.uri | http://hdl.handle.net/10722/280541 | - |
dc.description.abstract | In a prospective, double-blind, randomised controlled trial, we compared the efficacy of patient-controlled analgesia using remifentanil (25-30 μg per bolus) with intramuscular pethidine (50-75 mg) for labour analgesia in 69 parturients. Parturients receiving patient-controlled analgesia reported less pain than those receiving intramuscular pethidine throughout the study period (p < 0.001), with maximal reduction in visual analogue pain score at 2 h after commencement of analgesia (mean (SD) 20 (17) in the patient-controlled analgesia group and 36 (22) in the intramuscular pethidine group. The median (95% CI) time to the first request for rescue analgesics was significantly longer with patient-controlled analgesia (8.0 (6.8-9.2) h) compared with intramuscular pethidine (4.9 (3.8-5.4) h, p < 0.001). Maternal satisfaction scores were also higher with remifentanil compared with intramuscular pethidine (p= 0.001). There was no report of sedation, aponea or oxygen desaturation in either group, and Apgar scores were similar between groups. We conclude that patient-controlled analgesia with remifentanil provides better labour analgesia and maternal satisfaction than intramuscular pethidine. At this dose, maternal and fetal side effects were uncommon. © 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland. | - |
dc.language | eng | - |
dc.relation.ispartof | Anaesthesia | - |
dc.title | A double-blind randomised comparison of intravenous patient-controlled remifentanil with intramuscular pethidine for labour analgesia | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/j.1365-2044.2011.06790.x | - |
dc.identifier.pmid | 21707564 | - |
dc.identifier.scopus | eid_2-s2.0-80051787049 | - |
dc.identifier.volume | 66 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 796 | - |
dc.identifier.epage | 801 | - |
dc.identifier.eissn | 1365-2044 | - |
dc.identifier.isi | WOS:000293794800008 | - |
dc.identifier.f1000 | 13293973 | - |
dc.identifier.issnl | 0003-2409 | - |