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Article: Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol

TitleSystematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
Authors
Keywordsoncology
paediatric oncology
primary care
acupressure
adult
Issue Date2019
PublisherBMJ Publishing Group: BMJ Open. The Journal's web site is located at http://bmjopen.bmj.com
Citation
BMJ Open, 2019, v. 9 n. 10, p. article no. e031834 How to Cite?
AbstractIntroduction: Nausea and vomiting are two most common symptoms reported by children with cancer when they undergo active treatment. However, pharmacological treatment is not sufficient to manage these two symptoms, with over 40% of children still experience nausea and vomiting after receiving antiemetics. There has been an exponential growth of studies to demonstrate the effectiveness of different complementary complementary medicine (CAM) to control nausea and vomiting during cancer treatment. Appropriate application of CAM enhances the effectiveness of antiemetics, thus reducing the symptom burden on children as well as improving their general condition and quality of life during cancer treatment. Nevertheless, it remains unclear which CAM is the best approach to help children to prevent or reduce nausea and vomiting during and after cancer treatment. This paper describes a protocol for identifying, analysing and synthesising research evidence on the effectiveness of CAM on nausea and vomiting in children with cancer. Methods and analysis: A total of 10 databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials which meet the inclusion criteria will be included. The primary outcome is the changes in nausea and vomiting either assessed by self-reported and/or objective measures. Review Manager 5.3 will be used to synthesise the data, calculate the treatment effects, perform any subgroup analysis and assess the risk of bias. Ethical and dissemination: The results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required. PROSPERO registration number CRD42019135404.
Persistent Identifierhttp://hdl.handle.net/10722/281702
ISSN
2019 Impact Factor: 2.496
2015 SCImago Journal Rankings: 1.448
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorHo, KY-
dc.contributor.authorLam, KKW-
dc.contributor.authorChung, JOK-
dc.contributor.authorXia, W-
dc.contributor.authorCHEUNG, AT-
dc.contributor.authorHO, LK-
dc.contributor.authorChiu, SY-
dc.contributor.authorChan, GCF-
dc.contributor.authorLi, HCW-
dc.date.accessioned2020-03-22T04:18:31Z-
dc.date.available2020-03-22T04:18:31Z-
dc.date.issued2019-
dc.identifier.citationBMJ Open, 2019, v. 9 n. 10, p. article no. e031834-
dc.identifier.issn2044-6055-
dc.identifier.urihttp://hdl.handle.net/10722/281702-
dc.description.abstractIntroduction: Nausea and vomiting are two most common symptoms reported by children with cancer when they undergo active treatment. However, pharmacological treatment is not sufficient to manage these two symptoms, with over 40% of children still experience nausea and vomiting after receiving antiemetics. There has been an exponential growth of studies to demonstrate the effectiveness of different complementary complementary medicine (CAM) to control nausea and vomiting during cancer treatment. Appropriate application of CAM enhances the effectiveness of antiemetics, thus reducing the symptom burden on children as well as improving their general condition and quality of life during cancer treatment. Nevertheless, it remains unclear which CAM is the best approach to help children to prevent or reduce nausea and vomiting during and after cancer treatment. This paper describes a protocol for identifying, analysing and synthesising research evidence on the effectiveness of CAM on nausea and vomiting in children with cancer. Methods and analysis: A total of 10 databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials which meet the inclusion criteria will be included. The primary outcome is the changes in nausea and vomiting either assessed by self-reported and/or objective measures. Review Manager 5.3 will be used to synthesise the data, calculate the treatment effects, perform any subgroup analysis and assess the risk of bias. Ethical and dissemination: The results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required. PROSPERO registration number CRD42019135404.-
dc.languageeng-
dc.publisherBMJ Publishing Group: BMJ Open. The Journal's web site is located at http://bmjopen.bmj.com-
dc.relation.ispartofBMJ Open-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectoncology-
dc.subjectpaediatric oncology-
dc.subjectprimary care-
dc.subjectacupressure-
dc.subjectadult-
dc.titleSystematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol-
dc.typeArticle-
dc.identifier.emailXia, W: xiavive@hku.hk-
dc.identifier.emailChan, GCF: gcfchan@hku.hk-
dc.identifier.emailLi, HCW: william3@hkucc.hku.hk-
dc.identifier.authorityChan, GCF=rp00431-
dc.identifier.authorityLi, HCW=rp00528-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1136/bmjopen-2019-031834-
dc.identifier.pmid31628132-
dc.identifier.pmcidPMC6803108-
dc.identifier.scopuseid_2-s2.0-85073634214-
dc.identifier.scopuseid_2-s2.0-85073634214-
dc.identifier.hkuros309435-
dc.identifier.volume9-
dc.identifier.issue10-
dc.identifier.spagearticle no. e031834-
dc.identifier.epagearticle no. e031834-
dc.publisher.placeUnited Kingdom-

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