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- Publisher Website: 10.1016/j.jdent.2020.103343
- Scopus: eid_2-s2.0-85084239135
- PMID: 32339601
- WOS: WOS:000542430200007
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Article: Impact of hypo-salivation on severe tooth wear: A ten-year cohort of patients received radiotherapy for nasopharyngeal carcinoma
Title | Impact of hypo-salivation on severe tooth wear: A ten-year cohort of patients received radiotherapy for nasopharyngeal carcinoma |
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Authors | |
Keywords | Tooth wear Tooth surface loss Saliva Clinical trial |
Issue Date | 2020 |
Publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent |
Citation | Journal of Dentistry, 2020, v. 97, p. article no. 103343 How to Cite? |
Abstract | Objectives:
This study was conducted to examine the tooth wear status of nasopharyngeal-carcinoma (NPC) patients who had received radiotherapy at least 5-year previously, and to investigate the salivary parameters that may be associated with the tooth wear.
Methods:
Tooth wear status of NPC survivors were clinically assessed using the Exact Tooth Wear Index. A tooth was graded to have severe wear when more than one-third of its buccal/occlusal/lingual surface had dentine loss. At the subject-level, percentages of anterior/posterior/all teeth with severe wear were calculated. Age, number of teeth, flow-rate/buffering capacity/pH of stimulated whole (SWS) and parotid (SPS) saliva’s were collected. Correlation and multiple-linear regression tests were performed at the significance level α = 0.05.
Result:
Sixty-eight participants (mean age of 60.0 ± 8.9), 697 anterior and 686 posterior teeth were examined with a mean of 10-years post-radiotherapy. Severe tooth wear was found in 63 (92.6 percent) participants, 288 anterior and 83 posterior teeth. The mean percentage of anterior/posterior/all teeth with severe wear were 42.3 ± 28.1, 14.5 ± 19.9 and 30.0 ± 21.7. Anterior teeth, particularly the incisal surface of central incisors were most affected. The mean flow-rate of SWS and SPS were 0.1 ± 0.1 ml/min and 0.03 ± 0.07 ml/min respectively. Thirty (44.1 percent) and 48 (70.6 percent) participants were found to have low/no buffering capacity of SWS and SPS respectively. Multiple-regression analyses revealed the SWS flow-rate was associated with the percentage of anterior teeth with severe wear (p=0.03).
Conclusion:
Anterior tooth wear is a significant dental problem among NPC survivors and was associated with hypo-salivation.
Clinical significance:
Patients with hypo-salivation should be being monitored for tooth wear particularly on the anterior teeth. |
Persistent Identifier | http://hdl.handle.net/10722/283704 |
ISSN | 2023 Impact Factor: 4.8 2023 SCImago Journal Rankings: 1.313 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lam, YHW | - |
dc.contributor.author | Tse, AKL | - |
dc.contributor.author | Tew, IM | - |
dc.contributor.author | Man, WHC | - |
dc.contributor.author | Botelho, MG | - |
dc.contributor.author | Pow, EHN | - |
dc.date.accessioned | 2020-07-03T08:22:56Z | - |
dc.date.available | 2020-07-03T08:22:56Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Journal of Dentistry, 2020, v. 97, p. article no. 103343 | - |
dc.identifier.issn | 0300-5712 | - |
dc.identifier.uri | http://hdl.handle.net/10722/283704 | - |
dc.description.abstract | Objectives: This study was conducted to examine the tooth wear status of nasopharyngeal-carcinoma (NPC) patients who had received radiotherapy at least 5-year previously, and to investigate the salivary parameters that may be associated with the tooth wear. Methods: Tooth wear status of NPC survivors were clinically assessed using the Exact Tooth Wear Index. A tooth was graded to have severe wear when more than one-third of its buccal/occlusal/lingual surface had dentine loss. At the subject-level, percentages of anterior/posterior/all teeth with severe wear were calculated. Age, number of teeth, flow-rate/buffering capacity/pH of stimulated whole (SWS) and parotid (SPS) saliva’s were collected. Correlation and multiple-linear regression tests were performed at the significance level α = 0.05. Result: Sixty-eight participants (mean age of 60.0 ± 8.9), 697 anterior and 686 posterior teeth were examined with a mean of 10-years post-radiotherapy. Severe tooth wear was found in 63 (92.6 percent) participants, 288 anterior and 83 posterior teeth. The mean percentage of anterior/posterior/all teeth with severe wear were 42.3 ± 28.1, 14.5 ± 19.9 and 30.0 ± 21.7. Anterior teeth, particularly the incisal surface of central incisors were most affected. The mean flow-rate of SWS and SPS were 0.1 ± 0.1 ml/min and 0.03 ± 0.07 ml/min respectively. Thirty (44.1 percent) and 48 (70.6 percent) participants were found to have low/no buffering capacity of SWS and SPS respectively. Multiple-regression analyses revealed the SWS flow-rate was associated with the percentage of anterior teeth with severe wear (p=0.03). Conclusion: Anterior tooth wear is a significant dental problem among NPC survivors and was associated with hypo-salivation. Clinical significance: Patients with hypo-salivation should be being monitored for tooth wear particularly on the anterior teeth. | - |
dc.language | eng | - |
dc.publisher | Elsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent | - |
dc.relation.ispartof | Journal of Dentistry | - |
dc.subject | Tooth wear | - |
dc.subject | Tooth surface loss | - |
dc.subject | Saliva | - |
dc.subject | Clinical trial | - |
dc.title | Impact of hypo-salivation on severe tooth wear: A ten-year cohort of patients received radiotherapy for nasopharyngeal carcinoma | - |
dc.type | Article | - |
dc.identifier.email | Lam, YHW: retlaw@hku.hk | - |
dc.identifier.email | Botelho, MG: botelho@hkucc.hku.hk | - |
dc.identifier.email | Pow, EHN: ehnpow@hku.hk | - |
dc.identifier.authority | Lam, YHW=rp02183 | - |
dc.identifier.authority | Botelho, MG=rp00033 | - |
dc.identifier.authority | Pow, EHN=rp00030 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.jdent.2020.103343 | - |
dc.identifier.pmid | 32339601 | - |
dc.identifier.scopus | eid_2-s2.0-85084239135 | - |
dc.identifier.hkuros | 310659 | - |
dc.identifier.volume | 97 | - |
dc.identifier.spage | article no. 103343 | - |
dc.identifier.epage | article no. 103343 | - |
dc.identifier.isi | WOS:000542430200007 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0300-5712 | - |