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Article: The functional role of surface molecules on extracellular vesicles in cancer, autoimmune diseases, and coagulopathy

TitleThe functional role of surface molecules on extracellular vesicles in cancer, autoimmune diseases, and coagulopathy
Authors
Keywordscancer
cytokines
extracellular vesicles
Issue Date2020
PublisherFederation of American Societies for Experimental Biology. The Journal's web site is located at http://www.jleukbio.org/
Citation
Journal of Leukocyte Biology, 2020, Epub 2020-06-01 How to Cite?
AbstractExtracellular vesicles (EVs) are nanosized particles that have emerged as mediators for intercellular communication in physiologic and pathologic conditions. EVs carry signaling information on their bilipid membrane as well as cargo within, allowing them to perform a wide range of biologic processes and contribute to pathophysiologic roles in a wide range of diseases, including cancer, autoimmune diseases and coagulopathy. This review will specifically address the function of surface molecules on EVs under normal and diseased conditions, as well as their potential to emerge as therapeutic targets in clinical settings, and the importance of further research on the surface topography of EVs.
Persistent Identifierhttp://hdl.handle.net/10722/284098
ISSN
2021 Impact Factor: 6.011
2020 SCImago Journal Rankings: 1.819
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, KCK-
dc.contributor.authorLam, MKN-
dc.contributor.authorChim, CS-
dc.contributor.authorChan, GCF-
dc.contributor.authorLi, JCB-
dc.date.accessioned2020-07-20T05:56:04Z-
dc.date.available2020-07-20T05:56:04Z-
dc.date.issued2020-
dc.identifier.citationJournal of Leukocyte Biology, 2020, Epub 2020-06-01-
dc.identifier.issn0741-5400-
dc.identifier.urihttp://hdl.handle.net/10722/284098-
dc.description.abstractExtracellular vesicles (EVs) are nanosized particles that have emerged as mediators for intercellular communication in physiologic and pathologic conditions. EVs carry signaling information on their bilipid membrane as well as cargo within, allowing them to perform a wide range of biologic processes and contribute to pathophysiologic roles in a wide range of diseases, including cancer, autoimmune diseases and coagulopathy. This review will specifically address the function of surface molecules on EVs under normal and diseased conditions, as well as their potential to emerge as therapeutic targets in clinical settings, and the importance of further research on the surface topography of EVs.-
dc.languageeng-
dc.publisherFederation of American Societies for Experimental Biology. The Journal's web site is located at http://www.jleukbio.org/-
dc.relation.ispartofJournal of Leukocyte Biology-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Postprint This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.-
dc.subjectcancer-
dc.subjectcytokines-
dc.subjectextracellular vesicles-
dc.titleThe functional role of surface molecules on extracellular vesicles in cancer, autoimmune diseases, and coagulopathy-
dc.typeArticle-
dc.identifier.emailChim, CS: jcschim@hku.hk-
dc.identifier.emailChan, GCF: gcfchan@hku.hk-
dc.identifier.emailLi, JCB: jamesli@hku.hk-
dc.identifier.authorityChim, CS=rp00408-
dc.identifier.authorityChan, GCF=rp00431-
dc.identifier.authorityLi, JCB=rp00496-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/JLB.3MR0420-067R-
dc.identifier.pmid32480430-
dc.identifier.scopuseid_2-s2.0-85085703167-
dc.identifier.hkuros311457-
dc.identifier.volumeEpub 2020-06-01-
dc.identifier.isiWOS:000536718000001-
dc.publisher.placeUnited States-
dc.identifier.issnl0741-5400-

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