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Article: Prevalence and Incidence of Dementia in People with Diabetes Mellitus

TitlePrevalence and Incidence of Dementia in People with Diabetes Mellitus
Authors
KeywordsDementia
diabetes mellitus
epidemiology
incidence
prevalence
Issue Date2020
PublisherIOS Press. The Journal's web site is located at http://www.iospress.nl/html/13872877.php
Citation
Journal of Alzheimer's Disease, 2020, v. 75 n. 2, p. 607-615 How to Cite?
AbstractBackground:Few studies have shown that an increased risk of dementia is associated with diabetes mellitus. Objective:To estimate the prevalence and incidence of dementia in people with diabetes in primary care in the UK. Methods:We conducted a descriptive study using the UK The Health Improvement Network (THIN) database. People diagnosed with diabetes from 2000 to 2016 were included in the study. Prevalence and incidence rates of dementia were calculated annually, stratified by age and gender. Results:The prevalence of dementia was 0.424% [95% CI (0.420%–0.427%)] in 2000 and 2.508% [95% CI (2.501%–2.515%)] in 2016. The highest prevalence was in those aged 85+ from 2.9% [95% CI (2.890%–2.974%)] in 2000 to 11.3% [95% CI (11.285%–11.384%)] in 2016. The incidence of dementia increased 3.7 times, from 0.181 cases per 100 persons [95% CI (0.179–0.183)] in 2000 to 0.683 cases per 100 persons [95% CI (0.679–0.686)] in 2016, respectively. Women had a higher prevalence and incidence of dementia than men 3.138% [95% CI (3.127%–3.150%)] versus 2.014% [95% CI (2.006%–2.022%)] and 0.820 [95% CI (0.814–0.826)] versus 0.576 cases per 100 persons [95% CI (0.571–0.580)] in 2016, respectively. Conclusion:There was a trend of increasing prevalence and incidence of dementia in people with diabetes over the period of 2000 to 2016. This study adds to the evidence on dementia prevalence and incidence, particularly in the diabetic population.
Persistent Identifierhttp://hdl.handle.net/10722/284938
ISSN
2019 Impact Factor: 3.909
2015 SCImago Journal Rankings: 1.774

 

DC FieldValueLanguage
dc.contributor.authorAlsharif, AA-
dc.contributor.authorWei, L-
dc.contributor.authorMa, T-
dc.contributor.authorMan, KCK-
dc.contributor.authorLau, WCY-
dc.contributor.authorBrauer, R-
dc.contributor.authorAlmetwazi, M-
dc.contributor.authorHoward, R-
dc.contributor.authorWong, ICK-
dc.date.accessioned2020-08-07T09:04:36Z-
dc.date.available2020-08-07T09:04:36Z-
dc.date.issued2020-
dc.identifier.citationJournal of Alzheimer's Disease, 2020, v. 75 n. 2, p. 607-615-
dc.identifier.issn1387-2877-
dc.identifier.urihttp://hdl.handle.net/10722/284938-
dc.description.abstractBackground:Few studies have shown that an increased risk of dementia is associated with diabetes mellitus. Objective:To estimate the prevalence and incidence of dementia in people with diabetes in primary care in the UK. Methods:We conducted a descriptive study using the UK The Health Improvement Network (THIN) database. People diagnosed with diabetes from 2000 to 2016 were included in the study. Prevalence and incidence rates of dementia were calculated annually, stratified by age and gender. Results:The prevalence of dementia was 0.424% [95% CI (0.420%–0.427%)] in 2000 and 2.508% [95% CI (2.501%–2.515%)] in 2016. The highest prevalence was in those aged 85+ from 2.9% [95% CI (2.890%–2.974%)] in 2000 to 11.3% [95% CI (11.285%–11.384%)] in 2016. The incidence of dementia increased 3.7 times, from 0.181 cases per 100 persons [95% CI (0.179–0.183)] in 2000 to 0.683 cases per 100 persons [95% CI (0.679–0.686)] in 2016, respectively. Women had a higher prevalence and incidence of dementia than men 3.138% [95% CI (3.127%–3.150%)] versus 2.014% [95% CI (2.006%–2.022%)] and 0.820 [95% CI (0.814–0.826)] versus 0.576 cases per 100 persons [95% CI (0.571–0.580)] in 2016, respectively. Conclusion:There was a trend of increasing prevalence and incidence of dementia in people with diabetes over the period of 2000 to 2016. This study adds to the evidence on dementia prevalence and incidence, particularly in the diabetic population.-
dc.languageeng-
dc.publisherIOS Press. The Journal's web site is located at http://www.iospress.nl/html/13872877.php-
dc.relation.ispartofJournal of Alzheimer's Disease-
dc.subjectDementia-
dc.subjectdiabetes mellitus-
dc.subjectepidemiology-
dc.subjectincidence-
dc.subjectprevalence-
dc.titlePrevalence and Incidence of Dementia in People with Diabetes Mellitus-
dc.typeArticle-
dc.identifier.emailMan, KCK: mkckth@hku.hk-
dc.identifier.emailLau, WCY: wallisy@hku.hk-
dc.identifier.emailWong, ICK: wongick@hku.hk-
dc.identifier.authorityWong, ICK=rp01480-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3233/JAD-191115-
dc.identifier.pmid32310163-
dc.identifier.scopuseid_2-s2.0-85085263890-
dc.identifier.hkuros311744-
dc.identifier.volume75-
dc.identifier.issue2-
dc.identifier.spage607-
dc.identifier.epage615-
dc.publisher.placeNetherlands-

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