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- Publisher Website: 10.1086/517429
- Scopus: eid_2-s2.0-17344363192
- PMID: 9607855
- WOS: WOS:000073771500038
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Article: High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia
Title | High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia |
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Authors | |
Issue Date | 1998 |
Citation | Journal of Infectious Diseases, 1998, v. 177, n. 6, p. 1715-1718 How to Cite? |
Abstract | A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV-8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV-8 sVCA was greatest in patients with KS (95%), followed by family members (39%) and a Sardinian control population age- and sex-matched to the relatives (11%). Within families, prevalence of antibodies was about equal among spouses, children, and siblings of KS patients, a finding that raises the possibilities of intrafamilial person- to-person or vertical transmission. Antibodies were detected 2-3 times more frequently in males than in females. The data show that prevalence of antibodies to HHV-8 sVCA correlates with the distribution of classic KS in a high- incidence area. Clustering of seroprevalence within some families suggests the presence of familial risk factors for active HHV-8 infection. |
Persistent Identifier | http://hdl.handle.net/10722/285591 |
ISSN | 2023 Impact Factor: 5.0 2023 SCImago Journal Rankings: 2.387 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Angeloni, Antonio | - |
dc.contributor.author | Heston, Lee | - |
dc.contributor.author | Uccini, Stefania | - |
dc.contributor.author | Sirianni, Maria Caterina | - |
dc.contributor.author | Cottoni, Francesca | - |
dc.contributor.author | Masala, Maria Vittoria | - |
dc.contributor.author | Cerimele, Decio | - |
dc.contributor.author | Lin, Su Fang | - |
dc.contributor.author | Sun, Ren | - |
dc.contributor.author | Rigsby, Michael | - |
dc.contributor.author | Faggioni, Alberto | - |
dc.contributor.author | Miller, George | - |
dc.date.accessioned | 2020-08-18T04:56:08Z | - |
dc.date.available | 2020-08-18T04:56:08Z | - |
dc.date.issued | 1998 | - |
dc.identifier.citation | Journal of Infectious Diseases, 1998, v. 177, n. 6, p. 1715-1718 | - |
dc.identifier.issn | 0022-1899 | - |
dc.identifier.uri | http://hdl.handle.net/10722/285591 | - |
dc.description.abstract | A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV-8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV-8 sVCA was greatest in patients with KS (95%), followed by family members (39%) and a Sardinian control population age- and sex-matched to the relatives (11%). Within families, prevalence of antibodies was about equal among spouses, children, and siblings of KS patients, a finding that raises the possibilities of intrafamilial person- to-person or vertical transmission. Antibodies were detected 2-3 times more frequently in males than in females. The data show that prevalence of antibodies to HHV-8 sVCA correlates with the distribution of classic KS in a high- incidence area. Clustering of seroprevalence within some families suggests the presence of familial risk factors for active HHV-8 infection. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Infectious Diseases | - |
dc.title | High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia | - |
dc.type | Article | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1086/517429 | - |
dc.identifier.pmid | 9607855 | - |
dc.identifier.scopus | eid_2-s2.0-17344363192 | - |
dc.identifier.volume | 177 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 1715 | - |
dc.identifier.epage | 1718 | - |
dc.identifier.isi | WOS:000073771500038 | - |
dc.identifier.issnl | 0022-1899 | - |