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Article: Understanding the interplay between host immunity and Epstein-Barr virus in NPC patients

TitleUnderstanding the interplay between host immunity and Epstein-Barr virus in NPC patients
Authors
Shen, YongZhang, SuzhanSun, RenWu, TingtingQian, Jing
KeywordsInnate immunity
EBV
Adaptive immunity
Immune evasion
NPC
Issue Date2015
Citation
Emerging Microbes and Infections, 2015, v. 4, n. 3, article no. e20 How to Cite?
DOI: http://dx.doi.org/10.1038/emi.2015.20
Abstract© 2015 SSCC. Epstein-Barr virus (EBV) has been used as a paradigm for studying host-virus interactions, not only because of its importance as a human oncogenic virus associated with several malignancies including nasopharyngeal carcinoma (NPC) but also owing to its sophisticated strategies to subvert the host antiviral responses. An understanding of the interplay between EBV and NPC is critical for the development of EBV-targeted immunotherapy. Here, we summarize the current knowledge regarding the host immune responses and EBV immune evasion mechanisms in the context of NPC.
Persistent Identifierhttp://hdl.handle.net/10722/285775
PubMed Central ID
PMC4395660
ISI Accession Number ID
WOS:000352313800002

 

DC FieldValueLanguage
dc.contributor.authorShen, Yong-
dc.contributor.authorZhang, Suzhan-
dc.contributor.authorSun, Ren-
dc.contributor.authorWu, Tingting-
dc.contributor.authorQian, Jing-
dc.date.accessioned2020-08-18T04:56:36Z-
dc.date.available2020-08-18T04:56:36Z-
dc.date.issued2015-
dc.identifier.citationEmerging Microbes and Infections, 2015, v. 4, n. 3, article no. e20-
dc.identifier.urihttp://hdl.handle.net/10722/285775-
dc.description.abstract© 2015 SSCC. Epstein-Barr virus (EBV) has been used as a paradigm for studying host-virus interactions, not only because of its importance as a human oncogenic virus associated with several malignancies including nasopharyngeal carcinoma (NPC) but also owing to its sophisticated strategies to subvert the host antiviral responses. An understanding of the interplay between EBV and NPC is critical for the development of EBV-targeted immunotherapy. Here, we summarize the current knowledge regarding the host immune responses and EBV immune evasion mechanisms in the context of NPC.-
dc.languageeng-
dc.relation.ispartofEmerging Microbes and Infections-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectInnate immunity-
dc.subjectEBV-
dc.subjectAdaptive immunity-
dc.subjectImmune evasion-
dc.subjectNPC-
dc.titleUnderstanding the interplay between host immunity and Epstein-Barr virus in NPC patients-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1038/emi.2015.20-
dc.identifier.pmid26038769-
dc.identifier.pmcidPMC4395660-
dc.identifier.scopuseid_2-s2.0-84979500468-
dc.identifier.volume4-
dc.identifier.issue3-
dc.identifier.spagearticle no. e20-
dc.identifier.epagearticle no. e20-
dc.identifier.eissn2222-1751-
dc.identifier.isiWOS:000352313800002-
dc.identifier.issnl2222-1751-

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