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- Publisher Website: 10.1016/j.ccell.2014.12.003
- Scopus: eid_2-s2.0-84963976664
- PMID: 25584888
- WOS: WOS:000347906900003
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Article: Breaking up is hard to do: PI3K isoforms on the rebound
| Title | Breaking up is hard to do: PI3K isoforms on the rebound |
|---|---|
| Authors | |
| Issue Date | 2015 |
| Citation | Cancer Cell, 2015, v. 27, n. 1, p. 5-7 How to Cite? |
| Abstract | © 2015 Elsevier Inc. In this issue of Cancer Cell, Schwartz and colleagues and Costa and colleagues demonstrate that inhibition ofPI3Ka or PI3Kb in cancer cells with hyperactivated PI3Ka or PI3Kb, respectively, activates the other isoform, leading to a ''rebound'' of the PI3K activity through different compensation mechanisms. |
| Persistent Identifier | http://hdl.handle.net/10722/292936 |
| ISSN | 2021 Impact Factor: 38.585 2020 SCImago Journal Rankings: 13.035 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Cescon, David W. | - |
| dc.contributor.author | Gorrini, Chiara | - |
| dc.contributor.author | Mak, Tak W. | - |
| dc.date.accessioned | 2020-11-17T14:57:32Z | - |
| dc.date.available | 2020-11-17T14:57:32Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | Cancer Cell, 2015, v. 27, n. 1, p. 5-7 | - |
| dc.identifier.issn | 1535-6108 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/292936 | - |
| dc.description.abstract | © 2015 Elsevier Inc. In this issue of Cancer Cell, Schwartz and colleagues and Costa and colleagues demonstrate that inhibition ofPI3Ka or PI3Kb in cancer cells with hyperactivated PI3Ka or PI3Kb, respectively, activates the other isoform, leading to a ''rebound'' of the PI3K activity through different compensation mechanisms. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Cancer Cell | - |
| dc.title | Breaking up is hard to do: PI3K isoforms on the rebound | - |
| dc.type | Article | - |
| dc.description.nature | link_to_OA_fulltext | - |
| dc.identifier.doi | 10.1016/j.ccell.2014.12.003 | - |
| dc.identifier.pmid | 25584888 | - |
| dc.identifier.scopus | eid_2-s2.0-84963976664 | - |
| dc.identifier.volume | 27 | - |
| dc.identifier.issue | 1 | - |
| dc.identifier.spage | 5 | - |
| dc.identifier.epage | 7 | - |
| dc.identifier.eissn | 1878-3686 | - |
| dc.identifier.isi | WOS:000347906900003 | - |
| dc.identifier.issnl | 1535-6108 | - |