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Conference Paper: Long Wavelength Light-triggered Drug Rlease Based on Triplet-triplet Energy Transfer

TitleLong Wavelength Light-triggered Drug Rlease Based on Triplet-triplet Energy Transfer
Authors
Lyu, WWang, W
Issue Date2019
Citation
10th International Conference on Materials for Advanced Technologies (ICMAT 2019), Singapore, 23-28 June 2019 How to Cite?
AbstractWe develop a new strategy that adopts long wavelength light-excitable photosensitizers to activate the cleavage of photocleavable prodrugs. The prodrugs are cleaved to release free drugs at their triplet excited (T1) state which is activated by photosensitizers through triplet-triplet energy transfer (TTET) process. We demonstrate that this strategy can increase the excitation wavelength while minimize the sacrifices of photocleavage quantum yield. This long wavelength light-triggered photocleavage strategy offers new solutions for spatiotemporal control of drug release.
DescriptionOrganizer: Materials Research Society of Singapore (MRS-S)
Persistent Identifierhttp://hdl.handle.net/10722/298645

 

DC FieldValueLanguage
dc.contributor.authorLyu, W-
dc.contributor.authorWang, W-
dc.date.accessioned2021-04-09T07:56:19Z-
dc.date.available2021-04-09T07:56:19Z-
dc.date.issued2019-
dc.identifier.citation10th International Conference on Materials for Advanced Technologies (ICMAT 2019), Singapore, 23-28 June 2019-
dc.identifier.urihttp://hdl.handle.net/10722/298645-
dc.descriptionOrganizer: Materials Research Society of Singapore (MRS-S)-
dc.description.abstractWe develop a new strategy that adopts long wavelength light-excitable photosensitizers to activate the cleavage of photocleavable prodrugs. The prodrugs are cleaved to release free drugs at their triplet excited (T1) state which is activated by photosensitizers through triplet-triplet energy transfer (TTET) process. We demonstrate that this strategy can increase the excitation wavelength while minimize the sacrifices of photocleavage quantum yield. This long wavelength light-triggered photocleavage strategy offers new solutions for spatiotemporal control of drug release.-
dc.languageeng-
dc.relation.ispartof10th International Conference on Materials for Advanced Technologies (ICMAT 2019)-
dc.titleLong Wavelength Light-triggered Drug Rlease Based on Triplet-triplet Energy Transfer-
dc.typeConference_Paper-
dc.identifier.emailLyu, W: lyuwen@hku.hk-
dc.identifier.emailWang, W: wangwp@hku.hk-
dc.identifier.authorityWang, W=rp02227-
dc.identifier.hkuros302214-

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