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Article: Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients

TitleCognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients
Authors
Lui, SSYLam, JPYLam, JWSChui, WWHMui, JHCSiu, BWMCheng, KMCheung, EFCChan, RCK
KeywordsCognitive insight
Medication adherence
Prospective memory
Schizophrenia
Issue Date2021
PublisherElsevier. The Journal's web site is located at http://www.sciencedirect.com/science/journal/18762018
Citation
Asian Journal of Psychiatry, 2021, v. 60, p. article no. 102644 How to Cite?
DOI: http://dx.doi.org/10.1016/j.ajp.2021.102644
AbstractObjective: Cognitive insight refers to the ability to distance oneself from and evaluate one's own beliefs and interpretations. Little is known about whether cognitive insight could influence medication adherence in schizophrenia patients. This study examined the role of cognitive insight in medication adherence and how it would interact with neuropsychological functions. Methods: Ninety clinically-stable schizophrenia patients completed the Beck’s Cognitive Insight Scale (BCIS) and tasks measuring prospective (PM) and other neurocognitive functions. Medication adherence was estimated using a multi-axial method comprising interview, clinician-rating, pharmacy refill record and pill counting. Correlational and regression analyses were conducted to examine whether cognitive insight and PM would be associated with mediation adherence. Post-hoc mediational analysis was performed to examine the interplay between cognitive insight, PM and medication adherence. Results: Clinical insight and cognitive insight together significantly influenced participants’ medication adherence, after neurocognitive functions and psychopathology were accounted for. Time-based PM, compared with other neurocognitive functions, affected medication adherence more strongly. Conclusions: Cognitive insight complements clinical insight in affecting medication adherence in schizophrenia patients.
Persistent Identifierhttp://hdl.handle.net/10722/299080
ISSN
1876-2018
2021 Impact Factor: 13.890
2020 SCImago Journal Rankings: 0.793
ISI Accession Number ID
WOS:000661285600006

 

DC FieldValueLanguage
dc.contributor.authorLui, SSY-
dc.contributor.authorLam, JPY-
dc.contributor.authorLam, JWS-
dc.contributor.authorChui, WWH-
dc.contributor.authorMui, JHC-
dc.contributor.authorSiu, BWM-
dc.contributor.authorCheng, KM-
dc.contributor.authorCheung, EFC-
dc.contributor.authorChan, RCK-
dc.date.accessioned2021-04-28T02:25:54Z-
dc.date.available2021-04-28T02:25:54Z-
dc.date.issued2021-
dc.identifier.citationAsian Journal of Psychiatry, 2021, v. 60, p. article no. 102644-
dc.identifier.issn1876-2018-
dc.identifier.urihttp://hdl.handle.net/10722/299080-
dc.description.abstractObjective: Cognitive insight refers to the ability to distance oneself from and evaluate one's own beliefs and interpretations. Little is known about whether cognitive insight could influence medication adherence in schizophrenia patients. This study examined the role of cognitive insight in medication adherence and how it would interact with neuropsychological functions. Methods: Ninety clinically-stable schizophrenia patients completed the Beck’s Cognitive Insight Scale (BCIS) and tasks measuring prospective (PM) and other neurocognitive functions. Medication adherence was estimated using a multi-axial method comprising interview, clinician-rating, pharmacy refill record and pill counting. Correlational and regression analyses were conducted to examine whether cognitive insight and PM would be associated with mediation adherence. Post-hoc mediational analysis was performed to examine the interplay between cognitive insight, PM and medication adherence. Results: Clinical insight and cognitive insight together significantly influenced participants’ medication adherence, after neurocognitive functions and psychopathology were accounted for. Time-based PM, compared with other neurocognitive functions, affected medication adherence more strongly. Conclusions: Cognitive insight complements clinical insight in affecting medication adherence in schizophrenia patients.-
dc.languageeng-
dc.publisherElsevier. The Journal's web site is located at http://www.sciencedirect.com/science/journal/18762018-
dc.relation.ispartofAsian Journal of Psychiatry-
dc.subjectCognitive insight-
dc.subjectMedication adherence-
dc.subjectProspective memory-
dc.subjectSchizophrenia-
dc.titleCognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients-
dc.typeArticle-
dc.identifier.emailLui, SSY: lsy570@hku.hk-
dc.identifier.emailLam, JPY: lpy759@HKUCC-COM.hku.hk-
dc.identifier.emailChui, WWH: cwh687@hku.hk-
dc.identifier.emailChan, RCK: rckchan@hkucc.hku.hk-
dc.identifier.authorityLui, SSY=rp02747-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ajp.2021.102644-
dc.identifier.pmid33862475-
dc.identifier.scopuseid_2-s2.0-85104067539-
dc.identifier.hkuros322210-
dc.identifier.volume60-
dc.identifier.spagearticle no. 102644-
dc.identifier.epagearticle no. 102644-
dc.identifier.isiWOS:000661285600006-
dc.publisher.placeThe Netherlands-

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