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- PMID: 33956140
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Article: Population Structure Limits Parallel Evolution in Sticklebacks
Title | Population Structure Limits Parallel Evolution in Sticklebacks |
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Authors | |
Keywords | Adaptation Genetic diversity Isolation by distance Population differentiation Parallel evolution Stickleback |
Issue Date | 2021 |
Publisher | Oxford University Press, published in association with Society for Molecular Biology and Evolution. The Journal's web site is located at http://mbe.oxfordjournals.org/ |
Citation | Molecular Biology and Evolution, 2021, v. 38 n. 10, p. 4205-4221 How to Cite? |
Abstract | Population genetic theory predicts that small effective population sizes (Ne) and restricted gene flow limit the potential for local adaptation. In particular, the probability of evolving similar phenotypes based on shared genetic mechanisms (i.e., parallel evolution), is expected to be reduced. We tested these predictions in a comparative genomic study of two ecologically similar and geographically codistributed stickleback species (viz. Gasterosteus aculeatus and Pungitius pungitius). We found that P. pungitius harbors less genetic diversity and exhibits higher levels of genetic differentiation and isolation-by-distance than G. aculeatus. Conversely, G. aculeatus exhibits a stronger degree of genetic parallelism across freshwater populations than P. pungitius: 2,996 versus 379 single nucleotide polymorphisms located within 26 versus 9 genomic regions show evidence of selection in multiple freshwater populations of G. aculeatus and P. pungitius, respectively. Most regions involved in parallel evolution in G. aculeatus showed increased levels of divergence, suggestive of selection on ancient haplotypes. In contrast, haplotypes involved in freshwater adaptation in P. pungitius were younger. In accordance with theory, the results suggest that connectivity and genetic drift play crucial roles in determining the levels and geographic distribution of standing genetic variation, providing evidence that population subdivision limits local adaptation and therefore also the likelihood of parallel evolution. |
Persistent Identifier | http://hdl.handle.net/10722/304377 |
ISSN | 2023 Impact Factor: 11.0 2023 SCImago Journal Rankings: 4.061 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Fang, B | - |
dc.contributor.author | Kemppainen, P | - |
dc.contributor.author | Momigliano, P | - |
dc.contributor.author | Merilä , J | - |
dc.date.accessioned | 2021-09-23T08:59:11Z | - |
dc.date.available | 2021-09-23T08:59:11Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Molecular Biology and Evolution, 2021, v. 38 n. 10, p. 4205-4221 | - |
dc.identifier.issn | 0737-4038 | - |
dc.identifier.uri | http://hdl.handle.net/10722/304377 | - |
dc.description.abstract | Population genetic theory predicts that small effective population sizes (Ne) and restricted gene flow limit the potential for local adaptation. In particular, the probability of evolving similar phenotypes based on shared genetic mechanisms (i.e., parallel evolution), is expected to be reduced. We tested these predictions in a comparative genomic study of two ecologically similar and geographically codistributed stickleback species (viz. Gasterosteus aculeatus and Pungitius pungitius). We found that P. pungitius harbors less genetic diversity and exhibits higher levels of genetic differentiation and isolation-by-distance than G. aculeatus. Conversely, G. aculeatus exhibits a stronger degree of genetic parallelism across freshwater populations than P. pungitius: 2,996 versus 379 single nucleotide polymorphisms located within 26 versus 9 genomic regions show evidence of selection in multiple freshwater populations of G. aculeatus and P. pungitius, respectively. Most regions involved in parallel evolution in G. aculeatus showed increased levels of divergence, suggestive of selection on ancient haplotypes. In contrast, haplotypes involved in freshwater adaptation in P. pungitius were younger. In accordance with theory, the results suggest that connectivity and genetic drift play crucial roles in determining the levels and geographic distribution of standing genetic variation, providing evidence that population subdivision limits local adaptation and therefore also the likelihood of parallel evolution. | - |
dc.language | eng | - |
dc.publisher | Oxford University Press, published in association with Society for Molecular Biology and Evolution. The Journal's web site is located at http://mbe.oxfordjournals.org/ | - |
dc.relation.ispartof | Molecular Biology and Evolution | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Adaptation | - |
dc.subject | Genetic diversity | - |
dc.subject | Isolation by distance | - |
dc.subject | Population differentiation | - |
dc.subject | Parallel evolution | - |
dc.subject | Stickleback | - |
dc.title | Population Structure Limits Parallel Evolution in Sticklebacks | - |
dc.type | Article | - |
dc.identifier.email | Merilä , J: merila@hku.hk | - |
dc.identifier.authority | Merilä , J=rp02753 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1093/molbev/msab144 | - |
dc.identifier.pmid | 33956140 | - |
dc.identifier.pmcid | PMC8476136 | - |
dc.identifier.scopus | eid_2-s2.0-85116129454 | - |
dc.identifier.hkuros | 324973 | - |
dc.identifier.volume | 38 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 4205 | - |
dc.identifier.epage | 4221 | - |
dc.identifier.isi | WOS:000715359700009 | - |
dc.publisher.place | United States | - |