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Article: The immune dysregulations in COVID-19: Implications for the management of rheumatic diseases

TitleThe immune dysregulations in COVID-19: Implications for the management of rheumatic diseases
Authors
Xiao, FHan, MZhu, XTang, YHuang, EZou, HJiang, QLu, L
KeywordsCOVID-19
immune dysregulation
management
rheumatic diseases
Issue Date2021
PublisherSpringer Japan. The Journal's web site is located at http://link.springer.de/link/service/journals/10165/index.htm
Citation
Modern Rheumatology, 2021, v. 31 n. 5, p. 927-932 How to Cite?
DOI: http://dx.doi.org/10.1080/14397595.2020.1868673
AbstractThe pandemic of COVID-19 has caused global social impact and high health risk. Clinical observations have suggested that elevated levels of inflammatory mediators are associated with disease severities in COVID-19 patients, in which the immunological profiles indicate the hyperactivation of innate immune cells and dysregulated adaptive immune responses. The increasing prevalence and disease progression of COVID-19 has emerged as a pressing challenge for the management of rheumatic patients with immune dysregulations. Here we review the immune dysregulations in COVID-19 and discuss the management of COVID-19 patients with rheumatic diseases.
Persistent Identifierhttp://hdl.handle.net/10722/305084
ISSN
1439-7595
2021 Impact Factor: 2.862
2020 SCImago Journal Rankings: 0.889
PubMed Central ID
PMC7852258
ISI Accession Number ID
WOS:000611636200001

 

DC FieldValueLanguage
dc.contributor.authorXiao, F-
dc.contributor.authorHan, M-
dc.contributor.authorZhu, X-
dc.contributor.authorTang, Y-
dc.contributor.authorHuang, E-
dc.contributor.authorZou, H-
dc.contributor.authorJiang, Q-
dc.contributor.authorLu, L-
dc.date.accessioned2021-10-05T02:39:30Z-
dc.date.available2021-10-05T02:39:30Z-
dc.date.issued2021-
dc.identifier.citationModern Rheumatology, 2021, v. 31 n. 5, p. 927-932-
dc.identifier.issn1439-7595-
dc.identifier.urihttp://hdl.handle.net/10722/305084-
dc.description.abstractThe pandemic of COVID-19 has caused global social impact and high health risk. Clinical observations have suggested that elevated levels of inflammatory mediators are associated with disease severities in COVID-19 patients, in which the immunological profiles indicate the hyperactivation of innate immune cells and dysregulated adaptive immune responses. The increasing prevalence and disease progression of COVID-19 has emerged as a pressing challenge for the management of rheumatic patients with immune dysregulations. Here we review the immune dysregulations in COVID-19 and discuss the management of COVID-19 patients with rheumatic diseases.-
dc.languageeng-
dc.publisherSpringer Japan. The Journal's web site is located at http://link.springer.de/link/service/journals/10165/index.htm-
dc.relation.ispartofModern Rheumatology-
dc.rightsThis version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/[insert DOI]-
dc.subjectCOVID-19-
dc.subjectimmune dysregulation-
dc.subjectmanagement-
dc.subjectrheumatic diseases-
dc.titleThe immune dysregulations in COVID-19: Implications for the management of rheumatic diseases-
dc.typeArticle-
dc.identifier.emailXiao, F: xiaof@hku.hk-
dc.identifier.emailHuang, E: heyhk49@hku.hk-
dc.identifier.emailLu, L: liweilu@hku.hk-
dc.identifier.authorityLu, L=rp00477-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1080/14397595.2020.1868673-
dc.identifier.pmid33427554-
dc.identifier.pmcidPMC7852258-
dc.identifier.scopuseid_2-s2.0-85099812607-
dc.identifier.hkuros326294-
dc.identifier.volume31-
dc.identifier.issue5-
dc.identifier.spage927-
dc.identifier.epage932-
dc.identifier.isiWOS:000611636200001-
dc.publisher.placeJapan-

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