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Article: Diagnosis of Zika virus infection on a nanotechnology platform

TitleDiagnosis of Zika virus infection on a nanotechnology platform
Authors
Zhang, BoPinsky, Benjamin A.Ananta, Jeyarama S.Zhao, SuArulkumar, ShylajaWan, HaoSahoo, Malaya K.Abeynayake, JanakiWaggoner, Jesse J.Hopes, ClayTang, MeijieDai, Hongjie
Issue Date2017
Citation
Nature Medicine, 2017, v. 23, n. 5, p. 548-550 How to Cite?
DOI: http://dx.doi.org/10.1038/nm.4302
AbstractWe developed a multiplexed assay on a plasmonic-gold platform for measuring IgG and IgA antibodies and IgG avidity against both Zika virus (ZIKV) and dengue virus (DENV) infections. In contrast to IgM cross-reactivity, IgG and IgA antibodies against ZIKV nonstructural protein 1 (NS1) antigen were specific to ZIKV infection, and IgG avidity revealed recent ZIKV infection and past DENV-2 infection in patients in dengue-endemic regions. This assay could enable specific diagnosis of ZIKV infection over other flaviviral infections.
Persistent Identifierhttp://hdl.handle.net/10722/334468
ISSN
1078-8956
2021 Impact Factor: 87.241
2020 SCImago Journal Rankings: 19.536

 

DC FieldValueLanguage
dc.contributor.authorZhang, Bo-
dc.contributor.authorPinsky, Benjamin A.-
dc.contributor.authorAnanta, Jeyarama S.-
dc.contributor.authorZhao, Su-
dc.contributor.authorArulkumar, Shylaja-
dc.contributor.authorWan, Hao-
dc.contributor.authorSahoo, Malaya K.-
dc.contributor.authorAbeynayake, Janaki-
dc.contributor.authorWaggoner, Jesse J.-
dc.contributor.authorHopes, Clay-
dc.contributor.authorTang, Meijie-
dc.contributor.authorDai, Hongjie-
dc.date.accessioned2023-10-20T06:48:21Z-
dc.date.available2023-10-20T06:48:21Z-
dc.date.issued2017-
dc.identifier.citationNature Medicine, 2017, v. 23, n. 5, p. 548-550-
dc.identifier.issn1078-8956-
dc.identifier.urihttp://hdl.handle.net/10722/334468-
dc.description.abstractWe developed a multiplexed assay on a plasmonic-gold platform for measuring IgG and IgA antibodies and IgG avidity against both Zika virus (ZIKV) and dengue virus (DENV) infections. In contrast to IgM cross-reactivity, IgG and IgA antibodies against ZIKV nonstructural protein 1 (NS1) antigen were specific to ZIKV infection, and IgG avidity revealed recent ZIKV infection and past DENV-2 infection in patients in dengue-endemic regions. This assay could enable specific diagnosis of ZIKV infection over other flaviviral infections.-
dc.languageeng-
dc.relation.ispartofNature Medicine-
dc.titleDiagnosis of Zika virus infection on a nanotechnology platform-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/nm.4302-
dc.identifier.pmid28263312-
dc.identifier.scopuseid_2-s2.0-85014540313-
dc.identifier.volume23-
dc.identifier.issue5-
dc.identifier.spage548-
dc.identifier.epage550-
dc.identifier.eissn1546-170X-

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