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Article: Clinical aspects of gut microbiota in hepatocellular carcinoma management

TitleClinical aspects of gut microbiota in hepatocellular carcinoma management
Authors
Xu, JZhan, QFan, YLo, EKKZhang, FYu, YEl-Nezami, HZeng, Z
KeywordsDysbiosis
Hepatocellular carcinoma
Microbiota
Probiotics
Issue Date1-Jul-2021
PublisherMDPI
Citation
Pathogens, 2021, v. 10, n. 7 How to Cite?
DOI: http://dx.doi.org/10.3390/pathogens10070782
Abstract

Liver cancer, predominantly hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths worldwide. Emerging data highlight the importance of gut homeostasis in the pathogenesis of HCC. Clinical and translational studies revealed the patterns of dysbiosis in HCC patients and their potential role for HCC diagnosis. Research on underlying mechanisms of dysbiosis in HCC development pointed out the direction for improving the treatment and prevention. Despite missing clinical studies, animal models showed that modulation of the gut microbiota by probiotics may become a new way to treat or prevent HCC development.


Persistent Identifierhttp://hdl.handle.net/10722/337202
ISSN
2076-0817
2021 Impact Factor: 4.531
2020 SCImago Journal Rankings: 0.984

 

DC FieldValueLanguage
dc.contributor.authorXu, J-
dc.contributor.authorZhan, Q-
dc.contributor.authorFan, Y-
dc.contributor.authorLo, EKK-
dc.contributor.authorZhang, F-
dc.contributor.authorYu, Y-
dc.contributor.authorEl-Nezami, H-
dc.contributor.authorZeng, Z-
dc.date.accessioned2024-03-11T10:18:52Z-
dc.date.available2024-03-11T10:18:52Z-
dc.date.issued2021-07-01-
dc.identifier.citationPathogens, 2021, v. 10, n. 7-
dc.identifier.issn2076-0817-
dc.identifier.urihttp://hdl.handle.net/10722/337202-
dc.description.abstract<p>Liver cancer, predominantly hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths worldwide. Emerging data highlight the importance of gut homeostasis in the pathogenesis of HCC. Clinical and translational studies revealed the patterns of dysbiosis in HCC patients and their potential role for HCC diagnosis. Research on underlying mechanisms of dysbiosis in HCC development pointed out the direction for improving the treatment and prevention. Despite missing clinical studies, animal models showed that modulation of the gut microbiota by probiotics may become a new way to treat or prevent HCC development.</p>-
dc.languageeng-
dc.publisherMDPI-
dc.relation.ispartofPathogens-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectDysbiosis-
dc.subjectHepatocellular carcinoma-
dc.subjectMicrobiota-
dc.subjectProbiotics-
dc.titleClinical aspects of gut microbiota in hepatocellular carcinoma management-
dc.typeArticle-
dc.identifier.doi10.3390/pathogens10070782-
dc.identifier.scopuseid_2-s2.0-85114386824-
dc.identifier.volume10-
dc.identifier.issue7-
dc.identifier.eissn2076-0817-
dc.identifier.issnl2076-0817-

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