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Article: Disseminated hepatosplenic mycobacterial infection masking myeloproliferative diseases as leukemoid reaction: A diagnostic pitfall

TitleDisseminated hepatosplenic mycobacterial infection masking myeloproliferative diseases as leukemoid reaction: A diagnostic pitfall
Authors
Au, WYMa, SKKwong, YL
KeywordsDisseminated mycobacterial infection
Leukemoid reaction
Myeloproliferative disease
Issue Date2001
PublisherInforma Healthcare. The Journal's web site is located at http://informahealthcare.com/loi/lal
Citation
Leukemia And Lymphoma, 2001, v. 42 n. 4, p. 805-808 How to Cite?
DOI: http://dx.doi.org/10.3109/10428190109099344
AbstractThe distinction of myeloproliferative disease (MPD) from leukemoid reactions due to reactive causes can be difficult. In the presence of simultaneous occurrence of MPD and an established infection, only the demonstration of a clonal marker or prolonged observation can substantiate the diagnosis. We present three cases of MPD presenting as leukemoid reaction due to disseminated hepatosplenic mycobacterial sepsis. There appeared to be an association between MPD and reduced resistance to mycobacterial infection. Clinicians and hematologist should be aware of such a predisposition and possible dual pathology for proper diagnosis, therapy and monitoring of both the infection and the myeloproliferation.
Persistent Identifierhttp://hdl.handle.net/10722/77710
ISSN
1042-8194
2021 Impact Factor: 2.996
2020 SCImago Journal Rankings: 0.961
ISI Accession Number ID
WOS:000170610100029
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorAu, WYen_HK
dc.contributor.authorMa, SKen_HK
dc.contributor.authorKwong, YLen_HK
dc.date.accessioned2010-09-06T07:34:53Z-
dc.date.available2010-09-06T07:34:53Z-
dc.date.issued2001en_HK
dc.identifier.citationLeukemia And Lymphoma, 2001, v. 42 n. 4, p. 805-808en_HK
dc.identifier.issn1042-8194en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77710-
dc.description.abstractThe distinction of myeloproliferative disease (MPD) from leukemoid reactions due to reactive causes can be difficult. In the presence of simultaneous occurrence of MPD and an established infection, only the demonstration of a clonal marker or prolonged observation can substantiate the diagnosis. We present three cases of MPD presenting as leukemoid reaction due to disseminated hepatosplenic mycobacterial sepsis. There appeared to be an association between MPD and reduced resistance to mycobacterial infection. Clinicians and hematologist should be aware of such a predisposition and possible dual pathology for proper diagnosis, therapy and monitoring of both the infection and the myeloproliferation.en_HK
dc.languageengen_HK
dc.publisherInforma Healthcare. The Journal's web site is located at http://informahealthcare.com/loi/lalen_HK
dc.relation.ispartofLeukemia and Lymphomaen_HK
dc.rightsLeukemia and Lymphoma. Copyright © Informa Healthcare.en_HK
dc.subjectDisseminated mycobacterial infection-
dc.subjectLeukemoid reaction-
dc.subjectMyeloproliferative disease-
dc.subject.meshAdulten_HK
dc.subject.meshCytogenetic Analysisen_HK
dc.subject.meshDiagnosis, Differentialen_HK
dc.subject.meshDiagnostic Errorsen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLeukemoid Reaction - diagnosis - microbiologyen_HK
dc.subject.meshLiver Diseases - microbiology - pathologyen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMycobacterium Infections - complications - diagnosisen_HK
dc.subject.meshMyeloproliferative Disorders - complications - diagnosisen_HK
dc.subject.meshSplenic Diseases - microbiology - pathologyen_HK
dc.titleDisseminated hepatosplenic mycobacterial infection masking myeloproliferative diseases as leukemoid reaction: A diagnostic pitfallen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1042-8194&volume=42&issue=4&spage=805&epage=808&date=2001&atitle=Disseminated+hepatosplenic+mycobacterial+infection+masking+myeloproliferative+diseases+as+leukemoid+reaction:+a+diagnostic+pitfallen_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3109/10428190109099344-
dc.identifier.pmid11697512en_HK
dc.identifier.scopuseid_2-s2.0-0034869944en_HK
dc.identifier.hkuros67876en_HK
dc.identifier.hkuros68017-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034869944&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume42en_HK
dc.identifier.issue4en_HK
dc.identifier.spage805en_HK
dc.identifier.epage808en_HK
dc.identifier.isiWOS:000170610100029-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridAu, WY=7202383089en_HK
dc.identifier.scopusauthoridMa, SK=9042504200en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.issnl1026-8022-

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