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Article: Pattern of recurrence after oesophageal resection for cancer: Clinical implications

TitlePattern of recurrence after oesophageal resection for cancer: Clinical implications
Authors
Issue Date1996
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.bjs.co.uk
Citation
British Journal Of Surgery, 1996, v. 83 n. 1, p. 107-111 How to Cite?
AbstractPatterns of disease recurrence were reviewed in 108 patients who had curative resection for squamous cell cancer of the thoracic oesophagus. At a median follow-up of 20 months, 56 patients (52 per cent) had recurrence. Most presented within 2 years. Extrathoracic recurrence was found in 41 per cent of patients and intrathoracic recurrence in 25 per cent. Systemic organ metastases (26 per cent) were as frequent as intrathoracic recurrences. Twelve patients (11 per cent) developed cervical lymph node (CLN recurrence; their mean time to recurrence was 12.6 months, compared with 13.1 months of recurrence at locations other than the neck (P = 0.8). Median survival was 23 and 13 months respectively (P = 0.27). Preoperative chemotherapy lowered the recurrence rate from 60 per cent to 30 per cent, (P = 0.01) but did not affect survival. The addition of cervical lymphadenectomy would benefit few patients and must be counterbalanced with increased morbidity and cost. The frequency of systemic organ metastases calls for further investigation of the possible benefits of chemotherapy.
Persistent Identifierhttp://hdl.handle.net/10722/84063
ISSN
2023 Impact Factor: 8.6
2023 SCImago Journal Rankings: 2.148
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, SYKen_HK
dc.contributor.authorFok, Men_HK
dc.contributor.authorWong, Jen_HK
dc.date.accessioned2010-09-06T08:48:29Z-
dc.date.available2010-09-06T08:48:29Z-
dc.date.issued1996en_HK
dc.identifier.citationBritish Journal Of Surgery, 1996, v. 83 n. 1, p. 107-111en_HK
dc.identifier.issn0007-1323en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84063-
dc.description.abstractPatterns of disease recurrence were reviewed in 108 patients who had curative resection for squamous cell cancer of the thoracic oesophagus. At a median follow-up of 20 months, 56 patients (52 per cent) had recurrence. Most presented within 2 years. Extrathoracic recurrence was found in 41 per cent of patients and intrathoracic recurrence in 25 per cent. Systemic organ metastases (26 per cent) were as frequent as intrathoracic recurrences. Twelve patients (11 per cent) developed cervical lymph node (CLN recurrence; their mean time to recurrence was 12.6 months, compared with 13.1 months of recurrence at locations other than the neck (P = 0.8). Median survival was 23 and 13 months respectively (P = 0.27). Preoperative chemotherapy lowered the recurrence rate from 60 per cent to 30 per cent, (P = 0.01) but did not affect survival. The addition of cervical lymphadenectomy would benefit few patients and must be counterbalanced with increased morbidity and cost. The frequency of systemic organ metastases calls for further investigation of the possible benefits of chemotherapy.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.bjs.co.uken_HK
dc.relation.ispartofBritish Journal of Surgeryen_HK
dc.rightsBritish Journal of Surgery. Copyright © John Wiley & Sons Ltd.en_HK
dc.titlePattern of recurrence after oesophageal resection for cancer: Clinical implicationsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1323&volume=83&spage=107&epage=111&date=1996&atitle=Pattern+of+recurrence+after+oesophageal+resection+for+cancer:+clinical+implicationsen_HK
dc.identifier.emailLaw, SYK: slaw@hku.hken_HK
dc.identifier.authorityLaw, SYK=rp00437en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/bjs.1800830134en_HK
dc.identifier.pmid8653330-
dc.identifier.scopuseid_2-s2.0-0029671019en_HK
dc.identifier.hkuros10781en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0029671019&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume83en_HK
dc.identifier.issue1en_HK
dc.identifier.spage107en_HK
dc.identifier.epage111en_HK
dc.identifier.isiWOS:A1996TP07900033-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLaw, SYK=7202241293en_HK
dc.identifier.scopusauthoridFok, M=7005879262en_HK
dc.identifier.scopusauthoridWong, J=7404435808en_HK
dc.identifier.issnl0007-1323-

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