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Article: The relation between protein degradation pathways and Parkinson's disease

TitleThe relation between protein degradation pathways and Parkinson's disease
Authors
Zhu, G-QCheng, Y-FWang, MLiu, J-GLi, Q-L
KeywordsAutophagy
Chaprone-Mediated Autophagy Pathway
Parkinson's Disease
Phytoestrogen
Ubiquitin-Proteasome System
Issue Date2008
Citation
Chinese Pharmacological Bulletin, 2008, v. 24 n. 12, p. 1561-1564 How to Cite?
AbstractLewy bodies are one hallmark of Parkinson's disease. α-synuclein is a typical component in the Lewy bodies. Recently, the relationship between neuron degeneration diseases and the protein accumulation in neurons has already been verified, especially in Parkinson's disease. Degradation is one way to defend largely accumulating protein. Ubiquitin-proteasome system and chaprone-mediated autophagy pathway are two key protein degradation pathways, which are responsible for degradation soluble protein. This paper aims sum up the relationship between the protein degradation pathways and Parkinson's disease, and has also referred to the protective strategy of phytoestrogen to Parkinson's disease.
Persistent Identifierhttp://hdl.handle.net/10722/91238
ISSN
1001-1978
2020 SCImago Journal Rankings: 0.169
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorZhu, G-Qen_HK
dc.contributor.authorCheng, Y-Fen_HK
dc.contributor.authorWang, Men_HK
dc.contributor.authorLiu, J-Gen_HK
dc.contributor.authorLi, Q-Len_HK
dc.date.accessioned2010-09-17T10:15:25Z-
dc.date.available2010-09-17T10:15:25Z-
dc.date.issued2008en_HK
dc.identifier.citationChinese Pharmacological Bulletin, 2008, v. 24 n. 12, p. 1561-1564en_HK
dc.identifier.issn1001-1978en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91238-
dc.description.abstractLewy bodies are one hallmark of Parkinson's disease. α-synuclein is a typical component in the Lewy bodies. Recently, the relationship between neuron degeneration diseases and the protein accumulation in neurons has already been verified, especially in Parkinson's disease. Degradation is one way to defend largely accumulating protein. Ubiquitin-proteasome system and chaprone-mediated autophagy pathway are two key protein degradation pathways, which are responsible for degradation soluble protein. This paper aims sum up the relationship between the protein degradation pathways and Parkinson's disease, and has also referred to the protective strategy of phytoestrogen to Parkinson's disease.en_HK
dc.languageengen_HK
dc.relation.ispartofChinese Pharmacological Bulletinen_HK
dc.subjectAutophagyen_HK
dc.subjectChaprone-Mediated Autophagy Pathwayen_HK
dc.subjectParkinson's Diseaseen_HK
dc.subjectPhytoestrogenen_HK
dc.subjectUbiquitin-Proteasome Systemen_HK
dc.titleThe relation between protein degradation pathways and Parkinson's diseaseen_HK
dc.typeArticleen_HK
dc.identifier.emailCheng, Y:yuecheng@hku.hken_HK
dc.identifier.authorityCheng, Y=rp1320en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-60749121031en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-60749121031&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1561en_HK
dc.identifier.epage1564en_HK
dc.identifier.issnl1001-1978-

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