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Article: Performance of serial time-encoded amplified microscope
Title | Performance of serial time-encoded amplified microscope |
---|---|
Authors | |
Issue Date | 2010 |
Publisher | Optical Society of America. The Journal's web site is located at http://www.opticsexpress.org |
Citation | Optics Express, 2010, v. 18 n. 10, p. 10016-10028 How to Cite? |
Abstract | Serial time-encoded amplified microscopy (STEAM) is an entirely new imaging modality that enables ultrafast continuous real-time imaging with high sensitivity. By means of optical image amplification, STEAM overcomes the fundamental tradeoff between sensitivity and speed that affects virtually all optical imaging systems. Unlike the conventional microscope systems, the performance of STEAM depends not only on the lenses, but also on the properties of other components that are unique to STEAM, namely the spatial disperser, the group velocity dispersion element, and the back-end electronic digitizer. In this paper, we present an analysis that shows how these considerations affect the spatial resolution, and how they create a trade-off between the number of pixels and the frame rate of the STEAM imager. We also quantify how STEAM's optical image amplification feature improves the imaging sensitivity. These analyses not only provide valuable insight into the operation of STEAM technology but also serve as a blue print for implementation and optimization of this new imaging technology. ©2010 Optical Society of America. |
Persistent Identifier | http://hdl.handle.net/10722/91333 |
ISSN | 2023 Impact Factor: 3.2 2023 SCImago Journal Rankings: 0.998 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Tsia, KK | en_HK |
dc.contributor.author | Goda, K | en_HK |
dc.contributor.author | Capewell, D | en_HK |
dc.contributor.author | Jalali, B | en_HK |
dc.date.accessioned | 2010-09-17T10:17:12Z | - |
dc.date.available | 2010-09-17T10:17:12Z | - |
dc.date.issued | 2010 | en_HK |
dc.identifier.citation | Optics Express, 2010, v. 18 n. 10, p. 10016-10028 | en_HK |
dc.identifier.issn | 1094-4087 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/91333 | - |
dc.description.abstract | Serial time-encoded amplified microscopy (STEAM) is an entirely new imaging modality that enables ultrafast continuous real-time imaging with high sensitivity. By means of optical image amplification, STEAM overcomes the fundamental tradeoff between sensitivity and speed that affects virtually all optical imaging systems. Unlike the conventional microscope systems, the performance of STEAM depends not only on the lenses, but also on the properties of other components that are unique to STEAM, namely the spatial disperser, the group velocity dispersion element, and the back-end electronic digitizer. In this paper, we present an analysis that shows how these considerations affect the spatial resolution, and how they create a trade-off between the number of pixels and the frame rate of the STEAM imager. We also quantify how STEAM's optical image amplification feature improves the imaging sensitivity. These analyses not only provide valuable insight into the operation of STEAM technology but also serve as a blue print for implementation and optimization of this new imaging technology. ©2010 Optical Society of America. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Optical Society of America. The Journal's web site is located at http://www.opticsexpress.org | en_HK |
dc.relation.ispartof | Optics Express | en_HK |
dc.rights | Optics Express. Copyright © Optical Society of America. | - |
dc.rights | This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=oe-18-10-10016. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law. | - |
dc.subject.mesh | Amplifiers, Electronic | - |
dc.subject.mesh | Image Enhancement - instrumentation | - |
dc.subject.mesh | Lenses | - |
dc.subject.mesh | Microscopy - instrumentation | - |
dc.subject.mesh | Signal Processing, Computer-Assisted - instrumentation | - |
dc.title | Performance of serial time-encoded amplified microscope | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1094-4087&volume=18&issue=10&spage=10016&epage=10028&date=2010&atitle=Performance+of+serial+time-encoded+amplified+microscope | - |
dc.identifier.email | Tsia, KK:tsia@hku.hk | en_HK |
dc.identifier.authority | Tsia, KK=rp01389 | en_HK |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1364/OE.18.010016 | en_HK |
dc.identifier.pmid | 20588855 | - |
dc.identifier.scopus | eid_2-s2.0-77952747342 | en_HK |
dc.identifier.hkuros | 176032 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77952747342&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 18 | en_HK |
dc.identifier.issue | 10 | en_HK |
dc.identifier.spage | 10016 | en_HK |
dc.identifier.epage | 10028 | en_HK |
dc.identifier.isi | WOS:000277560000027 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Tsia, KK=6506659574 | en_HK |
dc.identifier.scopusauthorid | Goda, K=35227304100 | en_HK |
dc.identifier.scopusauthorid | Capewell, D=6603243853 | en_HK |
dc.identifier.scopusauthorid | Jalali, B=7004889917 | en_HK |
dc.identifier.issnl | 1094-4087 | - |