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Title	Author(s)	Issue Date
Activation of Hedgehog signaling improves neural crest derivation from human pluripotent stem cells as revealed by single-cell transcriptomics and a human innervated colonic organoid model Proceeding/Conference:Cell Symposium: Engineering Organoids and Organs, 2019	Lau, CST LI, Z Lui, NC Hui, CC Wells, J Ngan, ESW	2019
Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function Journal:Gastroenterology	Lai, FPL Lau, CST Wong, JKL Gui, H Wang, X Zhou, T Lai, KWH Tse, HF Tam, PKH Garcia-Barcelo, MM Ngan, ESW	2017
CRISPR-Cas9 mediated correction of Hirschsprung-associated mutations in human iPSC restores neural crest cell functions Proceeding/Conference:EMBO Conference: Advances in Stem Cells and Regenerative Medicine	Lau, CST Lai, PL Ngan, ESW	2017
Defective OXPHOS perturbs the neuronal differentiation of human enteric neural crest cells as revealed by the iPSC model of Hirschsprung disease and single-cell transcriptomic analysis [Poster presentation] Proceeding/Conference:International Society for Stem Cell Research Annual Meeting 2023 (14/06/2023-17/06/2023, Boston)	Li, Z Lui, KNC Lau, CST Lai, FPL Ngan, ESW	14-Jun-2023
Dynamic regulation of c-KIT+ population in neuroblastoma Proceeding/Conference:Hong Kong International Cancer Congress, HKICC 2011	Lau, CST Kwok, KM Tam, PKH Ngan, ESW	2011
Dysregulation of Gli Signaling Underlies Degective Enteric Nervous System Development Proceeding/Conference:Annual Meeting of the International Society for Stem Cell Research, ISSCR 2014	Liu, A Lau, CST Wong, KL Briscoe, J Hui, CC Ngan, ESW	2014
Endocrine-gland vascular endothelial growth factor (EG-VEGF) in neuroblastoma tumor initiating cells Proceeding/Conference:Advances in Neuroblastoma Research Conference, ANR 2010	Ngan, ESW Lau, CST Wo, YH Chan, WK Chan, GCF Wang, Y Kaplan, D Tam, PKH	2010
Establishment of experimental paradigm for generation of functioning enteric neurons from human pluripotent stem cells using single cell transcriptomics and human innervated colonic organoids Proceeding/Conference:International Society for Stem Cell Research (ISSCR) Annual Meeting, 2019	Lau, CST Li, Z Lai, PL Lui, NC Li, P Munera, J Mathe, M Wells, J Ngan, ESW	2019
Functional study of non-coding variants in Hirschsprung disease using human pluripotent stem cell-based model Proceeding/Conference:International Society for Stem Cell Research (ISSCR) Annual Meeting, 2019	Lui, NC Fu, AX Lai, PL Lau, CST Li, P Yip, KYL Ngan, ESW	2019
Generation of isogenic iPSC with RET mutation using CRISPR-Cas9 Proceeding/Conference:CiRA-ISSCR International Symposium	Lai, PL Lau, CST Ngan, ESW	2016
Gli, a family of novel Hirschsprung genes: discovery and mechanisms Proceeding/Conference:BAPS-IPEG 2014 Joint Congress	Liu, A Lau, CST Wong, KL Briscoe, J Hui, CC Garcia-Barcelo, MM Ngan, ESW Tam, PKH	2014
Greater variability in lipid measurements associated with cardiovascular disease and mortality: A 10‐year diabetes cohort study Journal:Diabetes, Obesity and Metabolism	Wan, EYF Yu, EYT Chin, WY Barrett, JK Mok, AHY Lau, CST Wang, Y Wong, ICK Chan, EWY Lam, CLK	2020
Greater variability in lipid measurements associated with kidney diseases in patients with type 2 diabetes mellitus in a 10-year diabetes cohort study Journal:Scientific Reports	Wan, EYF Yu, EYT Chin, WY Lau, CST Mok, AHY Wang, Y Wong, ICK Chan, EWY Lam, CLK	2021
Identification of Genes Associated with Hirschsprung Disease, Based on Whole-genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development Journal:Gastroenterology	Tang, SM Li, P Lai, PL Fu, A Lau, CST So, MT Lui, NC Li, Z Zhuang, X Yu, M	2018
Investigating the implications of RET variant/mutation in Hirschsprung disease pathogenesis using patient-specific iPSC Proceeding/Conference:CiRA-ISSCR International Symposium	Lau, CST Lai, PL Ngan, ESW	2016
iPSC-based disease model reveals defective APP processing by BACE2 as a novel disease mechanism underlying Hirschsprung Proceeding/Conference:The 5th International Symposium on Development of the Enteric Nervous System: cells, signals genes and therapy, 2018	Li, P Tang, SM Lau, CST Lai, PL Lui, NC Tam, PKH Garcia-Barcelo, MM Ngan, ESW	2018
Kruppel-like factor 4 suppresses neuroblastoma growth by promoting smooth-muscle differentiation Proceeding/Conference:International Society for Stem Cell Research Annual Meeting	Tsoi, LS Lau, CST Tam, P Ngan, E	2011
Modelling Hirschsprung disease with human pluripotent stem cell derived colonic organoids Proceeding/Conference:International Society for Stem Cell Research (ISSCR) Annual Meeting 2018	Lau, CST Lui, NC Lai, FPL Tam, PKH Ngan, ESW	2018
De novo population of c-KIT expressing cells sustains neuroblastoma progression Proceeding/Conference:EMBL Conference: Stem Cells in Cancer and Regenerative Medicine 2012	Lau, CST Ngan, ESW	2012
Potential use of patient specific induced-pluriopotent stem cell (iPSC) to delineate the molecular pathogenesis of syndromic Hirschsprung (HSCR) Proceeding/Conference:Annual Meeting of the International Society for Stem Cell Research, ISSCR 2013	Yung, JSY Wong, JKL Lau, CST Tse, HF Tam, P Garcia-Barcelo, MM Ngan, E	2013

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