Professor Wong is Co-Director of the Centre for Safe Medication Practice and Research, Department of Pharmacology & Pharmacy, and holder of the Lo Shiu Kwan Kan Po Ling Professorship in Pharmacy at HKU. He is Co-Director of the Centre for Medication Optimisation Research and Education (CMORE) at University College London Hospital and UCL School of Pharmacy.

His expertise is using big data research to investigate safety and optimum use of medications for treatment of various conditions specifically cardiovascular, neurological and psychological conditions. As part of this work, he conducts research at Queen Mary Hospital, Hong Kong to evaluate the safety and effectiveness of medication in patients with these and other illnesses

Professor Wong qualified as a pharmacist in 1992 and received his PhD from The University of Manchester in 1998 for his work at the David Lewis Centre for Epilepsy. In 2002, he was appointed as the Founding Director of the Centre for Paediatric Pharmacy Research at the School of Pharmacy, University of London, and the UCL Institute of Child Health and Great Ormond Street Hospital, which is recognised as a leading research centre in medicines for children.

After joining HKU in 2011 as Head of the Department of Pharmacology & Pharmacy, Professor Wong led the accreditation of the BPharm programme by the Pharmacy and Poisons Board of Hong Kong. He was also responsible for setting up the new Master of Clinical Pharmacy programme and the Centre for Safe Medication Practice and Research. The Centre for Safe Medication Practice and Research has focused on the methodological development and application of health big data research in Hong Kong. In 2015, in addition to his work at HKU, Professor Wong coordinate with collegues at the UCL School of Pharmacy to develop a joint research programme in pharmacoepidemiology and medication safety.

Professor Wong has also advised the Departments of Health in England and Hong Kong, the World Health Organization, the European Medicines Agency, and the pharmaceutical industry. He has over 500 peer-reviewed papers published in prominent journals including Nature portfolio journals, JAMA Network Journals, Lancet family journals and BMJ journals. Professor Wong was cited among the top 1% of scholars in the Clarivate Analytics' Essential Science Indicators in eight consecutive years between 2015 and 2022.

In recognition of his research, Professor Wong has received various awards and fellowships for his work as an academic pharmacist. He was awarded the Chemist and Druggist Pharmacy Practice Research Conference Medal from the Royal Pharmaceutical Society of Great Britain in 2004. He is the only pharmacist to date to have received a UK Department of Health Public Health Career Scientist Award in 2002. He was awarded an Honorary Fellowship from the Royal College of Paediatrics and Child Health in the UK in 2011, an Honorary Fellowship from the College of Pharmacy Practice in Hong Kong in 2013, and a Fellowship from the Royal Pharmaceutical Society of Great Britain in 2013, British Pharmacological Society 2019, International Society of Pharmacovigilance in 2019 and Faculty of Public Health of Royal Colleges of Physicians of the United Kingdom in 2021.

Professor Wong was Vice-President of the International Society of Pharmacovigilance between 2016 and 2019. He has also been an expert witness for many legal cases in the UK and Hong Kong regarding medication safety on behalf of victims of medication errors and adverse drug reactions, and for pharmaceutical companies.