Immunomodulatory effect of macrolides in naturally occurring influenza virus infections in the community

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Grant Data
Project Title
Immunomodulatory effect of macrolides in naturally occurring influenza virus infections in the community
Principal Investigator
Dr Ip, Dennis Kai Ming   (Principal Investigator (PI))
Co-Investigator(s)
Professor Cowling Benjamin John   (Co-Investigator)
Duration
36
Start Date
2018-10-01
Completion Date
2021-09-30
Amount
1151308
Conference Title
Immunomodulatory effect of macrolides in naturally occurring influenza virus infections in the community
Presentation Title
Keywords
Immunomodulation, Influenza, Macrolide, Treatment
Discipline
Clinical Trials,Epidemiology
Panel
Biology and Medicine (M)
HKU Project Code
17127218
Grant Type
General Research Fund (GRF)
Funding Year
2018
Status
Completed
Objectives
1 To examine the effect of macrolide antibiotics on the clinical course and resolution of disease in young adults with influenza virus infection 2 To examine the effect of macrolide antibiotics on pattern of influenza viral shedding in young adults with influenza virus infection 3 To examine the effect of macrolide antibiotics on patterns of plasma cytokine/ chemokine in young adults with influenza virus infection 4 To examine the effect of macrolide antibiotics on the carriage and antimicrobial resistance pattern of common respiratory pathogens in young adults with influenza virus infection