HKU Scholars Hub: Project

Molecular pathology of liver cancer - a multidisciplinary study

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Grant Data

Project Title

Molecular pathology of liver cancer - a multidisciplinary study

Principal Investigator

Professor Ng, Irene Oi Lin (Principal Investigator (PI))

Co-Investigator(s)

Professor Huang Jiandong (Collaborator)

Professor Guan Xin-Yuan (Co-Investigator)

Dr Cheung Siu Tim (Co-Investigator)

Dr Ching Yick Pang (Co-Investigator)

Emeritus Professor Lai Ching Lung (Collaborator)

Emeritus Professor Fan Sheung Tat (Collaborator)

Professor Poon Randy Yat Choi (Collaborator)

Professor Lai Po Shan (Collaborator)

Professor Ben-Neriah Yinon (Collaborator)

Professor Jin Dong-Yan (Co-Investigator)

Professor Poon Ronnie Tung Ping (Co-Investigator)

Professor Mak Tak Wah (Collaborator)

Duration

Start Date

2007-04-01

Amount

6400000

Conference Title

Molecular pathology of liver cancer - a multidisciplinary study

Presentation Title

Keywords

Molecular, multidisciplinary, Pathology

Discipline

Pathology

HKU Project Code

HKU 1/06C

Grant Type

Collaborative Research Fund (CRF) - Group Research Project

Funding Year

2006

Status

Completed

All Publications

Title	Author(s)	Issue Date	Views
Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery Journal:PLoS ONE	Wong, CM Wong, CCL Ng, YL Au, SLK Ko, FCF Ng, IOL	2011
Sequential alterations of microRNA expression in hepatocellular carcinoma development and venous metastasis Journal:Hepatology	Wong, CM Wong, CCL Lee, CMF Fan, DNY Au, SLK Ng, IOL	2012	154
Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1β, in mitotic checkpoint control in liver cancer Journal:Cancer Research	Sze, KMF Ching, YP Jin, DY Ng, IOL	2008
Role and significance of focal adhesion proteins in hepatocellular carcinoma Journal:Journal of Gastroenterology and Hepatology	Yam, JWP Tse, EYT Ng, IOL	2009	212
Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion Journal:Hepatology	Wong, CCL Wong, CM Tung, EKK Man, K Ng, IOL	2009	204
Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma Journal:Liver International	Hui, ICF Tung, EK Sze, KMF Ching, YP Ng, IOL	2010	204
Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis Journal:Cancer Research	Mak, GWY Chan, MML Leong, VYL Lee, JMF Yau, TO Ng, IOL Ching, YP	2011	173
Nuclear-targeted deleted in liver cancer 1 (DLC1) is less efficient in exerting its tumor suppressive activity both in vitro and in vivo Journal:PLoS ONE	Chan, LK Ko, FCF Sze, KMF Ng, IOL Yam, JWP	2011	210
N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H Journal:Journal of Cell Science	Chan, CP Mak, TY Chin, KT Ng, IOL Jin, DY	2010
MiR-130b promotes CD133 + liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1 Journal:Cell Stem Cell	Ma, S Tang, KH Chan, YP Lee, TK Kwan, PS Castilho, A Ng, I Man, K Wong, N To, KF Zheng, BJ Lai, PBS Lo, CM Chan, KW Guan, XY	2010	318