HKU Scholars Hub: Project

Molecular pathology of liver cancer - a multidisciplinary study

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Grant Data

Project Title

Molecular pathology of liver cancer - a multidisciplinary study

Principal Investigator

Professor Ng, Irene Oi Lin (Principal Investigator (PI))

Co-Investigator(s)

Dr Ching Yick Pang (Co-Investigator)

Dr Cheung Siu Tim (Co-Investigator)

Professor Guan Xin-Yuan (Co-Investigator)

Professor Poon Ronnie Tung Ping (Co-Investigator)

Professor Lai Po Shan (Collaborator)

Professor Poon Randy Yat Choi (Collaborator)

Professor Huang Jiandong (Collaborator)

Emeritus Professor Fan Sheung Tat (Collaborator)

Emeritus Professor Lai Ching Lung (Collaborator)

Professor Mak Tak Wah (Collaborator)

Professor Jin Dong-Yan (Co-Investigator)

Professor Ben-Neriah Yinon (Collaborator)

Duration

Start Date

2007-04-01

Amount

6400000

Conference Title

Molecular pathology of liver cancer - a multidisciplinary study

Presentation Title

Keywords

Molecular, multidisciplinary, Pathology

Discipline

Pathology

HKU Project Code

HKU 1/06C

Grant Type

External Grant

Funding Year

2006

Status

Completed

All Publications

Title	Author(s)	Issue Date	Views
Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery Journal:PLoS ONE	Wong, CM Wong, CCL Ng, YL Au, SLK Ko, FCF Ng, IOL	2011	118
Sequential alterations of microRNA expression in hepatocellular carcinoma development and venous metastasis Journal:Hepatology	Wong, CM Wong, CCL Lee, CMF Fan, DNY Au, SLK Ng, IOL	2012	123
Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1β, in mitotic checkpoint control in liver cancer Journal:Cancer Research	Sze, KMF Ching, YP Jin, DY Ng, IOL	2008	100
Role and significance of focal adhesion proteins in hepatocellular carcinoma Journal:Journal of Gastroenterology and Hepatology	Yam, JWP Tse, EYT Ng, IOL	2009	212
Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion Journal:Hepatology	Wong, CCL Wong, CM Tung, EKK Man, K Ng, IOL	2009	92
Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma Journal:Liver International	Hui, ICF Tung, EK Sze, KMF Ching, YP Ng, IOL	2010	131
Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis Journal:Cancer Research	Mak, GWY Chan, MML Leong, VYL Lee, JMF Yau, TO Ng, IOL Ching, YP	2011	116
Nuclear-targeted deleted in liver cancer 1 (DLC1) is less efficient in exerting its tumor suppressive activity both in vitro and in vivo Journal:PLoS ONE	Chan, LK Ko, FCF Sze, KMF Ng, IOL Yam, JWP	2011	118
N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H Journal:Journal of Cell Science	Chan, CP Mak, TY Chin, KT Ng, IOL Jin, DY	2010	104
MiR-130b promotes CD133 + liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1 Journal:Cell Stem Cell	Ma, S Tang, KH Chan, YP Lee, TK Kwan, PS Castilho, A Ng, I Man, K Wong, N To, KF Zheng, BJ Lai, PBS Lo, CM Chan, KW Guan, XY	2010	318