Name Card
Professor Lung, Maria Li 龍李梅瑞
Title:
Director, Laboratory of Cancer Molecular Genomics
Professor, Chair of Cancer Molecular Genomics, Clinical Oncology
Professor
Department:
Faculty:
Contact Information
Professor Lung, Maria Li 龍李梅瑞
Title:
Director, Laboratory of Cancer Molecular Genomics
Professor, Chair of Cancer Molecular Genomics, Clinical Oncology
Professor
Department:
Faculty:
Curriculum Vitae:
Research Interests:(click to check for cognate researchers)
Also Cited As:
Lung, M
Biography
Maria Lung attended Cornell University in New York for her bachelor’s degree and obtained her PhD from Stanford University in California. After being a postdoctoral fellow at the Massachusetts Institute of Technology in Massachusetts, she joined the Department of Microbiology at the University of Hong Kong. She subsequently moved to the Department of Biology at the Hong Kong University of Science & Technology and became one of its founding members. In 2009, she moved back to the University of Hong Kong and became Chair Professor in the Department of Clinical Oncology.
Honours, Awards & Prizes
| Awardees | Award Date | Honours / Awards / Prizes | Category |
|---|---|---|---|
| 2014-06-01 | Small Project Funding - “Pilot Study for Deciphering Methylome of Nasopharyngeal Carcinoma (NPC)” HK$51,732: University Research Committee | Research Achievement | |
| 2014-06-01 | Small Project Funding - “Study of alternative splicing of esophageal squamous cell carcinoma through transcriptome analysis in Hong Kong” HK$46,327: University Research Committee | Research Achievement | |
| 2015-02-01 | Small Project Funding - “Functional validation of a novel DUB3 somatic mutation in tumors of NPC” HK$80,000: HKU University Research Committee | Research Achievement | |
| 2015-02-01 | Small Project Funding - “Functional and mechanistic analysis of PHF11 in ESCC epigenetics” HK$42,256: HKU University Research Committee | Research Achievement | |
| 2014-02-01 | Seed Funding Programme for Basic Research - “Establishment of human nasopharyngeal carcinoma in 3D invasion and angiogenesis organotypic culture to study hypoxia-induced tumor invasion and angiogenesis” HK$47,900 | Research Achievement | |
| 2022-01-01 | (Co-I), “Redefining resectability for colorectal liver metastasis: the role of circulating tumor cells and its molecular characteristics” 2022-2025: Health Medical Research Fund | Research Achievement | |
| 2022-02-01 | (Co-I), “Understanding NPC Molecular Subtypes Associated with Clinical Outcome and Their Impact on Tumor Microenvironment” 2022-2025: Health Medical Research Fund | Research Achievement | |
| 2021-01-01 | (Co-I), "Clinical significance of real-time longitudinal monitoring of liquid biopsies for advanced colorectal cancer" 2021-2024: Health Medical Research Fund | Research Achievement | |
| 2020-07-01 | (Co-I), Health and Medical Research Fund, "Molecular classification based on microsatellite instability and RAS pathway status as prognostic biomarkers for risk stratification of metastatic relapse in colon carcinoma patients", HK$$1,499,750: Food and Health Bureau (FHB) | Research Achievement | |
| 2020-07-01 | (Co-I), Health and Medical Research Fund, "A Computational Framework Using Genomic and Transcriptomic Features for Predicting Resistance to PD-1/PDL-1 Checkpoint Inhibition in Gastrointestinal Tract (GIT) cancer", HK$851,952: Food and Health Bureau (FHB) | Research Achievement | |
| 2019-06-01 | (Co-I), Research grant, “Establishment of a patient-derived organoid in vivo drug testing model in ESCC and a pilot study for tumor-associated macrophage targeted therapy” HK$1,484,832: Health Medical Research Fund | Research Achievement | |
| 2020-01-01 | (Co-I), GRF research grant, “An Epigenetic Landscape Study: Unraveling the Role of Loss of CCCTC-binding Factor CTCF in Epigenetic Dysregulation in Epstein-Barr Virus-positive Nasopharyngeal Carcinoma” HK$1,100,023: Research Grants Council | Research Achievement | |
| 2019-01-01 | (Co-I), GRF research grant, “Genomic and functional study by targeting MST1R and its related chromosome 3p21.3 regions associated with genetic susceptibility in NPC” HK$956,853: Research Grants Council | Research Achievement | |
| 2020-01-01 | (Co-I), GRF research grant, “Redefining resectability for colorectal liver metastasis: the role of circulating tumor cells and its molecular characteristics” HK$820,060: Research Grants Council | Research Achievement | |
| 2014-05-01 | Advanced Study Institute: Croucher Foundation | Research Achievement | |
| 2014-06-01 | Research Grant 2013-2015 - “Genomic studies of esophageal squamous cell carcinoma familial genetic susceptibility and diagnostic biomarkers” HK$800,000: Asian Cancer Research Fund | Research Achievement | |
| 2014-05-01 | Advances in Nasopharyngeal Carcinoma Studies: Croucher Foundation Advanced Study Institute | Research Achievement | |
| 2014-06-01 | Research Grant 2013-2015 - “The SAA1 polymorphism vs risk factors in ESCC” $785,624 (Co-investigator): Health Medical Research Fund | Research Achievement | |
| 2010-06-01 | Molecular genetics and clinical advances in the study of esophageal and gastric cancers: Advanced Studies Institute: Croucher Foundation | Research Achievement | |
| 2014-06-01 | Research Grant 2014-2015 - “Genomic studies of esophageal squamous cell carcinoma familial genetic susceptibility and diagnostic biomarkers” HK$345,000: Asian Cancer Research Fund | Research Achievement | |
| 2014-06-01 | Research Grant 2013-2015 - “Elucidating the genetic basis for early-age onset NPC in Hong Kong” $1,000,000: Health Medical Research Fund | Research Achievement | |
| 2014-06-01 | GRF Research Grant 2014 - "Secretory NID2, a basement membrane protein facilitating cell adhesion, migration, and metastasis in human cancers" HK$1,122,210: Research Grants Council | Research Achievement | |
| 2005-03-01 | Croucher Senior Research Fellowship: Croucher Foundation | Research Achievement | |
| 2014-06-01 | Research Grant 2013-2015 - “Genetic studies of NPC” $2,155,000: Hong Kong Cancer Fund | Research Achievement | |
| 1992-01-01 | American Academy of Microbiology: American Academy of Microbiology | Research Achievement | |
| 2015-05-01 | Advanced Studies Institute: Croucher Foundation | Research Achievement | |
| 2015-02-01 | (Co-I), Research Grant 2015-2017 - “The effects of IKKbeta-specific inhibitor PS1145 on tumor formation and metastasis in NPC” HK$1,000,000: Health Medical Research Fund | Research Achievement | |
| 2014-12-01 | OncoSeek Dec 2014-Mar 2015, HK$650,000: Technology Start-up Support Scheme for Universities | Research Achievement | |
| 2015-06-01 | Gordon Research Conference, NPC Research Conference, $19,125 USD (2016, alternative years) | Research Achievement | |
| 2015-06-01 | OncoSeek 2015-2017, HK$860,000: Hong Kong Science Park Incubator program | Research Achievement | |
| 2015-02-01 | (Co-I), Research Grant 2015-2017 - “The clinical relevance of telomere attrition and NPC genetic susceptibility” HK$997,845: Health Medical Research Fund | Research Achievement | |
| 2015-04-01 | OncoSeek April 2015-Mar 2016, HK$300,000: Technology Start-up Support Scheme for Universities | Research Achievement | |
| 2015-11-01 | Corporate Sponsor: Lee’s Pharmaceutical (HK) Ltd. 2015-2017 - “Regulation and clinical implication of PD-L1 expression in esophageal tumor cells subjected to chemotherapy” HK$2,598,540: Innovation and Technology Commission | Research Achievement | |
| 2015-09-01 | GRF Research Grant (Competitive Earmarked Research Grant) 2015-2018 - “Functional and mechanistic characterizations of a Candidate Tumor Suppressor Gene, Mirror Image Polydactyly 1, in Nasopharyngeal Carcinoma” HK$971,461 (Transferred from PI to Co-I, due to departure of PI): Research Grants Council | Research Achievement | |
| 2016-06-01 | Research Grant 2016-2019 - “Targeted Genomics and Functional Studies of Novel Cancer Predisposing Genes for Esophageal Squamous Cell Carcinoma” HK$7,570,304: RGC Collaborative Research Fund | Research Achievement | |
| 2015-09-01 | GRF Research Grant 2015-2017 - “Functional and mechanistic investigation of frequent p53 gain-of-function mutations in esophageal squamous cell carcinoma” HK$1,168,311: Research Grants Council | Research Achievement | |
| 2017-04-01 | (CO-I), Research grant, "Optimizing the selection of patients with metastatic colorectal cancer for liver resection - An immuno-clinical scoring system incorporating circulating tumor cell enumeration and clinical factors" HK$946,064: Health Medical Research Fund | Research Achievement | |
| 2018-06-01 | Research grant, “Clinical application of enumeration and genomic characterization for non-invasive detection and real-time monitoring of circulating tumor cells for esophageal carcinoma” HK$1,199,732: Health Medical Research Fund | Research Achievement | |
| 2018-01-01 | (Co-I), GRF Research Grant, “Genomic and functional study of rare deleterious germline mutations in candidate genes associated with familial risk for esophageal carcinoma” HK$971,720: Research Grants Council | Research Achievement | |
| 2018-03-01 | “Non-invasive real-time monitoring and next-generation sequencing of circulating tumor cells for improved personalized treatment of metastatic colorectal cancer patients” HK$956,000: SK Yee Medical Foundation | Research Achievement | |
| 2017-06-01 | "Establishing platform technology for use of circulating tumor cells for cancer diagnostics & drug testing" HK$1,000,000: Platform Technology Funding | Research Achievement | |
| 2017-02-01 | "Centre for Nasopharyngeal Carcinoma Research" HK$707,783: FIL Foundation | Research Achievement | |
| 2017-07-01 | “Translational Studies for Elucidation the Tumor Heterogeneity and Molecular Evolution in Metastatic Gastrointestinal Tract Cancers for Personalized Medicine” HK$33,333,000: Theme-based Research Scheme | Research Achievement |
Professional Societies
| Term Period | Position | Professional Societies |
|---|---|---|
| 07/2009- | Expert Panel | Innovation and Technology Support Programme for Industry Department |
| 08/2010-07/2013 | Biomedical Engineering Programme Advisory Committee | CUHK |
| 07/2006-07/2012 | Technology Advisory Panel | Incu-Tech Program organized by Hong Kong Science and Technology Parks Corporation (HKSTP) |
| 2013-2020 | Reviewer | Grants Review Board for HMRF |
| 1992 | Fellow | Academy of Microbiology |
| 2017-2020 | Editorial Board member | Annals of Nasopharynx Cancer |
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