Professor Cheung, Annie Nga Yin 張雅賢
With advancements in morphologic and molecular techniques in the last few decades, the contribution of pathology to modern medicine has been enormous. Identification of the causes and pathogenesis of diseases enables focused preventive measures, better prediction of prognosis and development of personalised therapy for patients. The synergistic operation of anatomical and molecular pathology, the oldest and most advanced facets of pathology, has been the pivot stone for the modern transformation of clinical practice.
In the last decade, the incidence of “women’s cancers”, including ovarian and endometrial cancers, in Hong Kong have risen dramatically. On the other hand, while cervical cancer is a highly preventable disease, it is still a leading cause of death among Hong Kong women. Gestational trophoblastic disease, a disease that affect women of reproductive age, is locally prevalent.
Professor Annie Cheung is Clinical Professor at the Department of Pathology, The University of Hong Kong. She is the key pathologist for gynaecological histopathology and cytology in Queen Mary Hospital and the Pathologist in Charge of the HKU Cervical Cytology Laboratory, the first pathology laboratory in Hong Kong that is accredited by the College of American Pathologists. Professor Cheung is also the Director (Molecular Pathology) of the University Pathology Laboratory and the Chief of Service of Pathology, HKU-Shenzhen Hospital. To help patients on cancer prevention and treatment, state of the art laboratory techniques have been introduced.
Professor Cheung’s research focus is on genetic profiling and molecular signalling pathways, aiming at investigating diagnostic and prognostic markers as well as molecular targets for better therapy of patients with gynaecological cancers.
Professor Cheung’s research team is one of the first in the world to demonstrate the significance of genetic alterations in gestational trophoblastic disease. Significant findings in the studies of stem cell transcription factors and oncogenic signal pathways in ovarian and endometrial cancers as well as gestational trophoblastic disease have also been achieved. Her team is also successful in applying novel biomarkers for the early detection of cervical cancers.
She was a MBBS graduate of the University of Hong Kong in 1985 and continued her studies at HKU for her MD and PhD. Professor Cheung was trained in the Department of Obstetrics and Gynaecology at Queen Mary Hospital after graduation before joining the HKU Department of Pathology. She received postgraduate pathology training in the University of Manchester, UK, as well as Massachusetts General Hospital, Harvard Medical School and The Armed Forces Institute of Pathology, USA. She is a Fellow of the Royal College of Pathologists (UK) and Hong Kong Academy of Medicine (Pathology). Professor Cheung was appointed Clinical Professor in 2005.
Professor Cheung is currently Council Member of the International Federation for Cervical Pathology and Colposcopy, Regional Director for Asia in the World Association of Societies of Pathology & Laboratory Medicine Bureau, as well as Medical Consultant, International Academy of Cytology. Locally, Professor Cheung is the President of the Hong Kong College of Pathologists.
Professor Cheung has produced more than 250 publications including book chapters, review and original research articles in peer reviewed journals, such as PNAS and Lancet. She has served as a reviewer for 25 international journals and been on the editorial board of six medical journals.
Professor Cheung has received competitive research funding from overseas and local organisations as well as awards on education and research including the HKU University Teaching Fellow (Outstanding Teaching Award) and the Outstanding Research Student Supervisor Award as well as the Croucher Senior Medical Research Fellowship.
|Awardees||Award Date||Honours / Awards / Prizes||Category|
|2020-09-01||Faculty Outstanding Research Output Award: HKU Li Ka Shing Faculty of Medicine||Research Achievement|
|2013-03-01||2011-12 Outstanding Research Student Supervisor Award: HKU||Teaching Accomplishment|
|2005-07-01||University Teaching Fellow: The University of Hong Kong||Teaching Accomplishment|
|2005-01-01||Hong Kong West Cluster Outstanding Teams Award 2005 and the Certificate of Merit in Hospital Authority Outstanding Teams Award competition for Quality Assurance in Cytology: Hospital Authority, Hong Kong||Others|
|2010-09-01||Integrated Human Papilloma Virus Analysis as Adjunct for Triage of Atypical Cervical Cytology.: Health Research Symposium 2010, 11 Sept 2010 organised by Food and Health Bureau, HKSAR. - Best RFCID Poster Presentation Award||Research Achievement|
|2003-03-01||p73 expression and radiosensitivity in cervical carcinomas/Abstract/ AACR Scholar-in-training award: American Association for Cancer Research (AACR) 94th annual meeting||Research Achievement|
|1999-01-01||Sir Patrick Manson Gold Medal for Outstanding Merit in M.D Thesis (Title of MD thesis: Pathobiological study of Gestational Trophoblastic Disease): Sir Patrick Manson Gold Medal, The University of Hong Kong||Research Achievement|
|2006-04-10||Award for Innovative Excellence in Teaching, Learning & Technology: 17th International Conference on College Teaching and Learning||Teaching Accomplishment|
|1996-01-01||The Best Teachers Award (Medical Society): H.K.U.S.U.||Teaching Accomplishment|
|2002-01-01||Faculty Teaching Medal: Faculty of Medicine, The University of Hong Kong||Teaching Accomplishment|
|2009-01-01||Hong Kong West Cluster and Queen Mary Hospital Outstanding Teams Award 2009 for “Gynae-Oncology Team, QMH”: Hospital Authority, Hong Kong||Research Achievement|
|2014-04-01||Croucher Senior Medical Research Fellowship: The Croucher Foundation||Research Achievement|
|2003-01-01||Best Practice Care for Gynae-Oncology Patients and Families Team: Hospital Authority, Hong Kong||Others|
|Term Period||Position||Professional Societies|
|Member||International Society of Gynaecological Pathologists Subcommittee on Trophoblastic Disease|
|1997 - 2000||Member, Advacacy Group for Reproductive and Sexual Health for Hong Kong Women||Hong Kong Family Planning Association|
|International Academy of Cytology|
|2013||Member - Expert Panel in Cancer of the Cluster Coordinating Committee in Genetics||HONG KONG HOSPITAL AUTHORITY|
|Deputy Chairman||Chinese Medical Association, Subcommittee on Pathology of Female Genital Tract|
|2005 - present||President||Hong Kong Society of Colposcopy and Cervical Pathology|
|2000 - 2002||Council Member||Hong Kong Society of Cytology|
|Council Member||Asian Society of Gynecologic Oncology|
|American Society for Microbiology|
|American Association for Cancer Research|
|Deputy Chairman||Cross Straits Associationof Precision Medicine|
|Member - Cancer Expert Working Group (CEWG) on Cancer Prevention and Screening||Department of Health, HKSAR|
|2005 - present||Regional Representative||Asian Oceania Research on Genital Infections and Neoplasia|
|International Society for Gynaecological Cancer|
|Since 2012||President||International Society for the Study of Trophoblastic Disease|
|Founding board member||International Society of Precision Cancer Medicine|
|International Academy of Pathology|
|1996 - 1997||Council Member & Representative in the Hong Kong Federation of Medical Societies||The Hong Kong Pathology Society|
|Consultant||Professional Group on Gynaecological Pathology, Shenzhen medical Association|
|2013||College Representative - Tri-College Working Group on Medical Genetics Programme||Hong Kong College of Pathologists|
|2013 - 2017||President||Hong Kong College of Pathologists|
|Regional Director for Asia||World Association of Societies of Pathology & Laboratory Medicine (WASPaLM) Bureau|
|2011||Council member||International Federation for Cervical Pathology and Colposcopy|
|Royal College of Pathologists, UK|
|2019||Director||International Collaboration on Cancer Reporting (ICCR) Board of Directors|
|2019||Commissioner||Lancet Commission on Diagnostics|
|2019||Executive Vice-Chairman||Pathology Alliance of the Medical and Health Committee, the Council for the Promotion of Guangdong–Hong Kong–Macao Cooperation (广东省粤港澳合作促进会医药卫生大健康委员会病理联盟)|
|2016||Reviewer||Candidate for application of Professorship, Harvard Medical School|
|1999 - present||Member, Examination Sub-committee of the Licentiate Committee||The Hong Kong Medical Council|
|2007 - present||Member, Education and Accreditation Committee||The Hong Kong Medical Council|
|1994 - 1996||Chairman||The Hong Kong Pathology Society|
|1999 - 2003||Council member||Hong Kong College of Pathologists|
|1999 - present||Member, Speciality Advisory Panel (Anatomical Pathology)||Hong Kong College of Pathologists|
|2000 - 2002||Chairman, Quality Assurance Committee||Hong Kong College of Pathologists|
|2002 - present||Chief Examiner, Anatomical Pathology||Hong Kong College of Pathologists|
|20002- present||Inspector, Accreditation of Laboratory Training in Anatomical Pathology||Hong Kong College of Pathologists|
|1997 - present||Chairman, Training and Examination Committee||Hong Kong College of Pathologists|
|2003 - present||Member, Representative from the Hong Kong College of Pathologists in the Cytology Quality Assurance Programme Working Group||Hong Kong College of Pathologists|
|2008 - 2009||Deputy Registrar||Hong Kong College of Pathologists|
|2009 - 2013||Vice President||Hong Kong College of Pathologists|
|2006 - present||Member||Asian Cervical Cancer Prevention Advisory Broad (ACCPAB)|
|2004||Member, Interim Executive Board||Asian Oceania Research on Genital Infections and Neoplasia|
|2005 - present||Regional Representative||Asian Oceania Research on Genital Infections and Neoplasia|
|2004 - present||Interim Executive Board||Asian Oceania Research on Genital Infections and Neoplasia|
|2001 - 2004||Council Member, Executive Committee||International Society of Gynaecological Pathologists|
|2000 - 2004||Vice-President||Hong Kong Society of Colposcopy and Cervical Pathology|
|2007 - present||Member, Education Committee||Hong Kong Academy of Medicine|
|2005 - present||Advisor, GSK Asian Cervical Cancer Prevention Advisory Board||Asian Cervical Cancer Prevention Advisory Group|
|2005 - present||Advisor, MSD Asian Cervical Cancer Prevention Advisory Board||Asian Cervical Cancer Prevention Advisory Group|
|Colorectal Cancer Screening||Department of Health, HKSAR|
|Member - Colorectal Cancer Screening Pilot Programme Task Force||Department of Health, HKSAR|
|Hong Kong College of Pathologists|
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