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Conference Paper: Proton MRS of hepatic ischemia/reperfusion injury in an experimental rat model
| Title | Proton MRS of hepatic ischemia/reperfusion injury in an experimental rat model |
|---|---|
| Authors | |
| Issue Date | 2010 |
| Citation | The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. How to Cite? |
| Abstract | Hepatic ischemia/reperfusion injury (IRI) occurs during liver transplantation, tumor resection, hemorrhagic shock and veno-occlusive disease. Biochemical changes caused by hepatic IRI lead to hepatocellular remodeling, including cellular regeneration or irreversible programmed cell death. In this study, we demonstrated that the alteration in the metabolism of choline-containing compounds (CCC) accompanied with hepatic IRI could be monitored using 1H MRS. The CCC peak may be useful in evaluating the regeneration of hepatocytes upon hepatic IRI. 1H MRS has shown to be a potential tool for identify and quantify metabolic changes in liver in vivo noninvasively. |
| Description | Posters - MR Upper Abdomen I: No. 4581 |
| Persistent Identifier | http://hdl.handle.net/10722/129720 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chow, AMK | en_US |
| dc.contributor.author | Chan, KWY | en_US |
| dc.contributor.author | Fan, SJ | en_US |
| dc.contributor.author | Cheung, JSC | en_US |
| dc.contributor.author | Wu, EX | en_US |
| dc.date.accessioned | 2010-12-23T08:41:16Z | - |
| dc.date.available | 2010-12-23T08:41:16Z | - |
| dc.date.issued | 2010 | en_US |
| dc.identifier.citation | The ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden, 1-7 May 2010. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/129720 | - |
| dc.description | Posters - MR Upper Abdomen I: No. 4581 | - |
| dc.description.abstract | Hepatic ischemia/reperfusion injury (IRI) occurs during liver transplantation, tumor resection, hemorrhagic shock and veno-occlusive disease. Biochemical changes caused by hepatic IRI lead to hepatocellular remodeling, including cellular regeneration or irreversible programmed cell death. In this study, we demonstrated that the alteration in the metabolism of choline-containing compounds (CCC) accompanied with hepatic IRI could be monitored using 1H MRS. The CCC peak may be useful in evaluating the regeneration of hepatocytes upon hepatic IRI. 1H MRS has shown to be a potential tool for identify and quantify metabolic changes in liver in vivo noninvasively. | - |
| dc.language | eng | en_US |
| dc.relation.ispartof | ISMRM-ESMRMB Joint Annual Meeting | - |
| dc.title | Proton MRS of hepatic ischemia/reperfusion injury in an experimental rat model | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Chow, AMK: aprilcmk@hkusua.hku.hk | en_US |
| dc.identifier.email | Chan, KWY: kannie@graduate.hku.hk | - |
| dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
| dc.identifier.hkuros | 178230 | en_US |