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- Scopus: eid_2-s2.0-0024446456
- PMID: 2550863
- WOS: WOS:A1989AP22500007
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Article: In situ detection of Epstein-Barr virus markers in nasopharyngeal carcinoma patients
Title | In situ detection of Epstein-Barr virus markers in nasopharyngeal carcinoma patients |
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Authors | |
Keywords | Epstein–Barr virus In situ Nasopharyngeal carcinoma |
Issue Date | 1989 |
Publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/OCL |
Citation | Oncology, 1989, v. 46 n. 5, p. 310-317 How to Cite? |
Abstract | Cryosections of nasopharyngeal tissue from 9 patients suspected of having nasopharyngeal carcinoma (NPC) were examined for the presence of Epstein-Bar virus (EBV) markers in situ to assess virus infection in the nasopharynx. Viral DNA, EB nuclear antigen, and/or early antigens (EA.D and EA.R) were detected in 5 NPC specimens. EBV infection was not confined to the tumor areas of the biopsy specimens. Lymphoid cells and nontumor areas of these specimens contained EBV markers. In addition, nasopharyngeal tissues obtained from 3 of 4 patients in clinical remission for the disease showed evidence of EBV infection. |
Persistent Identifier | http://hdl.handle.net/10722/150688 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.832 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lung, ML | en_US |
dc.contributor.author | Chan, KH | en_US |
dc.contributor.author | Lam, WP | en_US |
dc.contributor.author | Kou, SK | en_US |
dc.contributor.author | Choy, D | en_US |
dc.contributor.author | Chan, CW | en_US |
dc.contributor.author | Ng, MH | en_US |
dc.date.accessioned | 2012-06-26T06:08:47Z | - |
dc.date.available | 2012-06-26T06:08:47Z | - |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Oncology, 1989, v. 46 n. 5, p. 310-317 | en_US |
dc.identifier.issn | 0030-2414 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/150688 | - |
dc.description.abstract | Cryosections of nasopharyngeal tissue from 9 patients suspected of having nasopharyngeal carcinoma (NPC) were examined for the presence of Epstein-Bar virus (EBV) markers in situ to assess virus infection in the nasopharynx. Viral DNA, EB nuclear antigen, and/or early antigens (EA.D and EA.R) were detected in 5 NPC specimens. EBV infection was not confined to the tumor areas of the biopsy specimens. Lymphoid cells and nontumor areas of these specimens contained EBV markers. In addition, nasopharyngeal tissues obtained from 3 of 4 patients in clinical remission for the disease showed evidence of EBV infection. | en_US |
dc.language | eng | en_US |
dc.publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/OCL | en_US |
dc.relation.ispartof | Oncology | en_US |
dc.subject | Epstein–Barr virus | - |
dc.subject | In situ | - |
dc.subject | Nasopharyngeal carcinoma | - |
dc.subject.mesh | Antibodies, Monoclonal - Diagnostic Use | en_US |
dc.subject.mesh | Antigens, Viral - Analysis | en_US |
dc.subject.mesh | Biopsy | en_US |
dc.subject.mesh | Dna, Viral - Analysis | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Fluorescent Antibody Technique | en_US |
dc.subject.mesh | Herpesvirus 4, Human | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Mucous Membrane - Microbiology | en_US |
dc.subject.mesh | Nasopharyngeal Neoplasms - Immunology - Microbiology | en_US |
dc.subject.mesh | Nucleic Acid Hybridization | en_US |
dc.title | In situ detection of Epstein-Barr virus markers in nasopharyngeal carcinoma patients | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lung, ML:mlilung@hku.hk | en_US |
dc.identifier.authority | Lung, ML=rp00300 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 2550863 | - |
dc.identifier.scopus | eid_2-s2.0-0024446456 | en_US |
dc.identifier.volume | 46 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 310 | en_US |
dc.identifier.epage | 317 | en_US |
dc.identifier.isi | WOS:A1989AP22500007 | - |
dc.publisher.place | Switzerland | en_US |
dc.identifier.scopusauthorid | Lung, ML=7006411788 | en_US |
dc.identifier.scopusauthorid | Chan, KH=35338760600 | en_US |
dc.identifier.scopusauthorid | Lam, WP=7203021904 | en_US |
dc.identifier.scopusauthorid | Kou, SK=7102161483 | en_US |
dc.identifier.scopusauthorid | Choy, D=7102939127 | en_US |
dc.identifier.scopusauthorid | Chan, CW=7404813871 | en_US |
dc.identifier.scopusauthorid | Ng, MH=7202076421 | en_US |
dc.identifier.issnl | 0030-2414 | - |