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Conference Paper: DTI detection of microstructural changes induced by sleep deprivation

TitleDTI detection of microstructural changes induced by sleep deprivation
Authors
Issue Date2012
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of 20th ISMRM, 2012, no. 0910 How to Cite?
AbstractRapid eye movement (REM) sleep is believed to be critical for memory consolidation. To probe the microstructural changes after sleep deprivation (SD) in vivo, REM-SD and DTI were employed in this study. Significant axial, radial and mean diffusivity decreases were found bilaterally in various locations in hippocampus, suggesting specific layers of hippocampus such as dentate gyrus and CA1 may be more susceptible to SD. Significant FA, axial and mean diffusivity decreases were also detected in cortex. Our results indicated that DTI is sensitive for probing microstructural changes, and can provide insights into the microstructural plasticity associated with sleep and memory.
DescriptionTheme: Adapting MR in a Changing World
Traditional Poster Session - Neuro A: Animal Models of Brain Disease Other Than Stroke: no. 0910
Persistent Identifierhttp://hdl.handle.net/10722/165174

 

DC FieldValueLanguage
dc.contributor.authorDing, AYen_US
dc.contributor.authorZhou, IYen_US
dc.contributor.authorLee, FYHen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2012-09-20T08:16:02Z-
dc.date.available2012-09-20T08:16:02Z-
dc.date.issued2012en_US
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of 20th ISMRM, 2012, no. 0910en_US
dc.identifier.urihttp://hdl.handle.net/10722/165174-
dc.descriptionTheme: Adapting MR in a Changing World-
dc.descriptionTraditional Poster Session - Neuro A: Animal Models of Brain Disease Other Than Stroke: no. 0910-
dc.description.abstractRapid eye movement (REM) sleep is believed to be critical for memory consolidation. To probe the microstructural changes after sleep deprivation (SD) in vivo, REM-SD and DTI were employed in this study. Significant axial, radial and mean diffusivity decreases were found bilaterally in various locations in hippocampus, suggesting specific layers of hippocampus such as dentate gyrus and CA1 may be more susceptible to SD. Significant FA, axial and mean diffusivity decreases were also detected in cortex. Our results indicated that DTI is sensitive for probing microstructural changes, and can provide insights into the microstructural plasticity associated with sleep and memory.-
dc.languageengen_US
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012en_US
dc.titleDTI detection of microstructural changes induced by sleep deprivationen_US
dc.typeConference_Paperen_US
dc.identifier.emailZhou, IY: iriszhou@eee.hku.hken_US
dc.identifier.emailLee, FYH: frankyhlee@gmail.com-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros207246en_US
dc.publisher.placeAustralia-
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of 20th ISMRM, 2012, no. 0910-

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