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Conference Paper: The genetic landscape of immune-competent and HIV lymphoma
Title | The genetic landscape of immune-competent and HIV lymphoma |
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Authors | Zhang, JGrubor, VLove, CLBanerjee, ARichards, KLMiezcowski, PDunphy, CHChoi, WWLAu, WYSrivastava, GLugar, PLRizzieri, DALagoo, ASBernal-Mizrachi, LMann, KPFlowers, CRNaresh, KNEvens, AMGordon, LICzader, MBGill, JIHsi, EDLiu, QFan, AWalsh, KJima, DDLuftig, MNi, TZhu, JChadburn, ALevy, SDunson, DBDave, SS |
Issue Date | 2011 |
Publisher | BioMed Central. The Journal's web site is located at http://www.infectagentscancer.com/home |
Citation | The 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICAMAOI), Bethesda, MD., 7-8 November 2011. In Infectious Agents and Cancer, 2011, v. 7 suppl. 1, article no. O1 How to Cite? |
Abstract | Burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL) are aggressive forms of lymphoma in adults and demonstrate overlapping morphology, immunophenotype and clinical behavior. The risk of developing these tumors increases ten to hundred-fold in the setting of HIV infection. The genetic causes and the role of specific mutations, especially in the setting of HIV, are largely unknown.
The decoding of the human genome and the advent of high-throughput sequencing have provided rich opportunities for the comprehensive identification of the genetic causes of cancer. In order to comprehensively identify genes that are recurrently mutated in immune-competent DLBCL and BL, we obtained a total of 92 cases of DLBCLs and 40 cases of BL. These cases were compared to a set of 5 DLBCLs and BL tumors derived from patients with HIV. The DLBCL cases were divided into a discovery set (N=34) and … |
Description | This journal supplement is Proceedings of the 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI) Open Access Journal |
Persistent Identifier | http://hdl.handle.net/10722/165453 |
ISSN | 2023 Impact Factor: 3.1 2023 SCImago Journal Rankings: 0.424 |
PubMed Central ID |
DC Field | Value | Language |
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dc.contributor.author | Zhang, J | en_US |
dc.contributor.author | Grubor, V | en_US |
dc.contributor.author | Love, CL | en_US |
dc.contributor.author | Banerjee, A | en_US |
dc.contributor.author | Richards, KL | en_US |
dc.contributor.author | Miezcowski, P | en_US |
dc.contributor.author | Dunphy, CH | en_US |
dc.contributor.author | Choi, WWL | en_US |
dc.contributor.author | Au, WY | en_US |
dc.contributor.author | Srivastava, G | en_US |
dc.contributor.author | Lugar, PL | en_US |
dc.contributor.author | Rizzieri, DA | en_US |
dc.contributor.author | Lagoo, AS | en_US |
dc.contributor.author | Bernal-Mizrachi, L | en_US |
dc.contributor.author | Mann, KP | en_US |
dc.contributor.author | Flowers, CR | en_US |
dc.contributor.author | Naresh, KN | en_US |
dc.contributor.author | Evens, AM | en_US |
dc.contributor.author | Gordon, LI | en_US |
dc.contributor.author | Czader, MB | en_US |
dc.contributor.author | Gill, JI | en_US |
dc.contributor.author | Hsi, ED | en_US |
dc.contributor.author | Liu, Q | en_US |
dc.contributor.author | Fan, A | en_US |
dc.contributor.author | Walsh, K | en_US |
dc.contributor.author | Jima, DD | en_US |
dc.contributor.author | Luftig, M | en_US |
dc.contributor.author | Ni, T | en_US |
dc.contributor.author | Zhu, J | en_US |
dc.contributor.author | Chadburn, A | en_US |
dc.contributor.author | Levy, S | en_US |
dc.contributor.author | Dunson, DB | en_US |
dc.contributor.author | Dave, SS | en_US |
dc.date.accessioned | 2012-09-20T08:18:20Z | - |
dc.date.available | 2012-09-20T08:18:20Z | - |
dc.date.issued | 2011 | en_US |
dc.identifier.citation | The 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICAMAOI), Bethesda, MD., 7-8 November 2011. In Infectious Agents and Cancer, 2011, v. 7 suppl. 1, article no. O1 | en_US |
dc.identifier.issn | 1750-9378 | - |
dc.identifier.uri | http://hdl.handle.net/10722/165453 | - |
dc.description | This journal supplement is Proceedings of the 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI) | - |
dc.description | Open Access Journal | - |
dc.description.abstract | Burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL) are aggressive forms of lymphoma in adults and demonstrate overlapping morphology, immunophenotype and clinical behavior. The risk of developing these tumors increases ten to hundred-fold in the setting of HIV infection. The genetic causes and the role of specific mutations, especially in the setting of HIV, are largely unknown. The decoding of the human genome and the advent of high-throughput sequencing have provided rich opportunities for the comprehensive identification of the genetic causes of cancer. In order to comprehensively identify genes that are recurrently mutated in immune-competent DLBCL and BL, we obtained a total of 92 cases of DLBCLs and 40 cases of BL. These cases were compared to a set of 5 DLBCLs and BL tumors derived from patients with HIV. The DLBCL cases were divided into a discovery set (N=34) and … | - |
dc.language | eng | en_US |
dc.publisher | BioMed Central. The Journal's web site is located at http://www.infectagentscancer.com/home | - |
dc.relation.ispartof | Infectious Agents and Cancer | en_US |
dc.rights | Infectious Agents and Cancer. Copyright © BioMed Central. | - |
dc.title | The genetic landscape of immune-competent and HIV lymphoma | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Choi, WWL: choiwl@hkucc.hku.hk | en_US |
dc.identifier.email | Au, WY: auwing@hkucc.hku.hk | en_US |
dc.identifier.email | Srivastava, G: sgopesh@hkucc.hku.hk | en_US |
dc.identifier.authority | Choi, WWL=rp00247 | en_US |
dc.identifier.authority | Srivastava, G=rp00365 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1186/1750-9378-7-S1-O1 | - |
dc.identifier.pmcid | PMC3330083 | - |
dc.identifier.hkuros | 210936 | en_US |
dc.identifier.hkuros | 213480 | - |
dc.identifier.volume | 7 | - |
dc.identifier.issue | suppl. 1 | - |
dc.publisher.place | United Kingdom | - |
dc.description.other | The 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICAMAOI), Bethesda, MD., 7-8 November 2011. In Infectious Agents and Cancer, 2011, v. 7 suppl. 1, article no. O1 | - |
dc.identifier.issnl | 1750-9378 | - |