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Conference Paper: Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver

TitleHematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver
Authors
Wang, XLo, CMChen, LCheung, CKYFan, ST
Issue Date2012
PublisherAmerican Association for Cancer Research.
Citation
The 103rd Annual Meeting of the American Association for Cancer Research (AACR 2012), Chicago, IL., 31 March-4 April 2012. How to Cite?
AbstractLiver transplantation (LT) is a cure for many liver diseases. Blood chimerism of donor origin can develop after LT, which raises the possibility of existence of hematopoietic stem/progenitor cells (HSPCs) in liver. We characterized the blood chimerism in a large cohort of 226 LT patients and analyzed putative HSPCs in adult human livers. The overall incidence of chimerism was 6.19%, of which 10.3% was among short-term (one day to six months) and 3.6% was among long-term (six months to eight years) LT patients. Hematopoietic Lin−CD34+CD38−CD90+ population has been demonstrated to generate long-term multipotent grafts in transplantations. In human adult livers, we detected ...
DescriptionPoster Session 12 - Cell of Origin and Plasticity of Cancer Stem Cells: abstract no. 3299
Persistent Identifierhttp://hdl.handle.net/10722/165655

 

DC FieldValueLanguage
dc.contributor.authorWang, Xen_US
dc.contributor.authorLo, CMen_US
dc.contributor.authorChen, Len_US
dc.contributor.authorCheung, CKY-
dc.contributor.authorFan, ST-
dc.date.accessioned2012-09-20T08:21:41Z-
dc.date.available2012-09-20T08:21:41Z-
dc.date.issued2012en_US
dc.identifier.citationThe 103rd Annual Meeting of the American Association for Cancer Research (AACR 2012), Chicago, IL., 31 March-4 April 2012.en_US
dc.identifier.urihttp://hdl.handle.net/10722/165655-
dc.descriptionPoster Session 12 - Cell of Origin and Plasticity of Cancer Stem Cells: abstract no. 3299-
dc.description.abstractLiver transplantation (LT) is a cure for many liver diseases. Blood chimerism of donor origin can develop after LT, which raises the possibility of existence of hematopoietic stem/progenitor cells (HSPCs) in liver. We characterized the blood chimerism in a large cohort of 226 LT patients and analyzed putative HSPCs in adult human livers. The overall incidence of chimerism was 6.19%, of which 10.3% was among short-term (one day to six months) and 3.6% was among long-term (six months to eight years) LT patients. Hematopoietic Lin−CD34+CD38−CD90+ population has been demonstrated to generate long-term multipotent grafts in transplantations. In human adult livers, we detected ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research.-
dc.relation.ispartofAnnual Meeting of the American Association for Cancer Research, AACR 2012en_US
dc.titleHematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liveren_US
dc.typeConference_Paperen_US
dc.identifier.emailWang, X: xqwang@hku.hken_US
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_US
dc.identifier.emailChen, L: chenlin@hku.hken_US
dc.identifier.emailCheung, CKY: cindycky@hku.hk-
dc.identifier.emailFan, ST: stfan@hku.hk-
dc.identifier.authorityWang, X=rp00507en_US
dc.identifier.authorityLo, CM=rp00412en_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros211339en_US
dc.publisher.placeUnited States-
dc.description.otherThe Annual Meeting of the American Association for Cancer Research (AACR 2012), Chicago, IL., 31 March-4 April 2012.-

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