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- Publisher Website: 10.1016/j.scitotenv.2012.07.099
- Scopus: eid_2-s2.0-84883453461
- PMID: 22959899
- WOS: WOS:000325831200130
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Article: Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay
Title | Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay |
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Authors | |
Keywords | Electronic waste Estimated daily intake Freshwater fish H4IIE-luc cell bioassay PCDD/Fs |
Issue Date | 2013 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/scitotenv |
Citation | Science of The Total Environment, 2013, v. 463-464, p. 1192-1200 How to Cite? |
Abstract | Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) via fish consumption in two major electronic (e) waste sites: Guiyu (GY), Guangdong Province and Taizhou (TZ), Zhejiang Province, and dioxin-like activity in fish determined by H4IIE-luc bioassay. In the present study, all fish were below EU's maximum allowable concentration in muscle of fish (4pg WHO-TEQ/g wet wt), except crucian (4.28pg WHO-TEQ/g wet wt) and silver carps (7.49pg WHO-TEQ/g wet wt) collected from GY rivers. Moreover, the residual concentration in bighead carp collected from GY (2.15pg WHO-TEQ/g wet wt) was close to the EU's action level (3pg WHO-TEQ/g wet wt) which gives 'early warning' to the competent authorities and operators to take measures to eliminate contamination. In addition, results indicated that the maximum human intake of PCDD/Fs via freshwater fish consumption in GY was 4.31pg WHO-TEQ/kg bw/day, which exceeds the higher end of the tolerable daily intake recommended by the WHO, EC-SCF and JECFA (1-4, 2 and 2.3pg WHO-TEQ/kg bw/day respectively). Furthermore, H4IIE-luc cell bioassay provides a very sensitive and cost-efficient screening tool for assessing the overall dioxin-like toxicity in the study, and is therefore valuable for high-throughput environmental monitoring studies. |
Persistent Identifier | http://hdl.handle.net/10722/165986 |
ISSN | 2023 Impact Factor: 8.2 2023 SCImago Journal Rankings: 1.998 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, JKY | en_US |
dc.contributor.author | Man, YB | en_US |
dc.contributor.author | Xing, GH | en_US |
dc.contributor.author | Wu, SC | en_US |
dc.contributor.author | Murphy, MB | en_US |
dc.contributor.author | Xu, Y | en_US |
dc.contributor.author | Wong, MH | en_US |
dc.date.accessioned | 2012-09-20T08:26:01Z | - |
dc.date.available | 2012-09-20T08:26:01Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | Science of The Total Environment, 2013, v. 463-464, p. 1192-1200 | en_US |
dc.identifier.issn | 0048-9697 | - |
dc.identifier.uri | http://hdl.handle.net/10722/165986 | - |
dc.description.abstract | Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) via fish consumption in two major electronic (e) waste sites: Guiyu (GY), Guangdong Province and Taizhou (TZ), Zhejiang Province, and dioxin-like activity in fish determined by H4IIE-luc bioassay. In the present study, all fish were below EU's maximum allowable concentration in muscle of fish (4pg WHO-TEQ/g wet wt), except crucian (4.28pg WHO-TEQ/g wet wt) and silver carps (7.49pg WHO-TEQ/g wet wt) collected from GY rivers. Moreover, the residual concentration in bighead carp collected from GY (2.15pg WHO-TEQ/g wet wt) was close to the EU's action level (3pg WHO-TEQ/g wet wt) which gives 'early warning' to the competent authorities and operators to take measures to eliminate contamination. In addition, results indicated that the maximum human intake of PCDD/Fs via freshwater fish consumption in GY was 4.31pg WHO-TEQ/kg bw/day, which exceeds the higher end of the tolerable daily intake recommended by the WHO, EC-SCF and JECFA (1-4, 2 and 2.3pg WHO-TEQ/kg bw/day respectively). Furthermore, H4IIE-luc cell bioassay provides a very sensitive and cost-efficient screening tool for assessing the overall dioxin-like toxicity in the study, and is therefore valuable for high-throughput environmental monitoring studies. | - |
dc.language | eng | en_US |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/scitotenv | - |
dc.relation.ispartof | Science of The Total Environment | en_US |
dc.subject | Electronic waste | - |
dc.subject | Estimated daily intake | - |
dc.subject | Freshwater fish | - |
dc.subject | H4IIE-luc cell bioassay | - |
dc.subject | PCDD/Fs | - |
dc.title | Dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans via fish consumption and dioxin-like activity in fish determined by H4IIE-luc bioassay | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chan, JKY: chanjky@hku.hk | en_US |
dc.identifier.email | Murphy, MB: mhwong@hkbu.edu.hk | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.scitotenv.2012.07.099 | - |
dc.identifier.pmid | 22959899 | - |
dc.identifier.scopus | eid_2-s2.0-84883453461 | - |
dc.identifier.hkuros | 210356 | en_US |
dc.identifier.isi | WOS:000325831200130 | - |
dc.publisher.place | Netherlands | - |
dc.identifier.issnl | 0048-9697 | - |