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Patent History
- ApplicationPC T/CN2007003005 2007-10-22
- PublicationWO 2008049330 2008-05-02
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published patent: USE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET
Title | USE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET |
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Priority Date | 2006-10-20 US 11/853404P |
Inventors | |
Issue Date | 2008 |
Citation | WO Published patent application WO 2008049330. World Intellectual Property Organization (WIPO), PatentScope, 2008 How to Cite? |
Abstract | Methods and compositions for identifying and treating obesity and obesity induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in mammalian subjects. The method includes measuring the concentration of circulating lipocalin-2 in a subject and comparing the measured level to lipocalin-2 to a reference level. Another aspect provides methods of treating insulin resistance, type 2 diabetes and other related complications by administering to a patient a composition that can reduce the circulating levels of lipocalin-2, for example a lipocalin-2 antagonist. |
Persistent Identifier | http://hdl.handle.net/10722/177123 |
References |
DC Field | Value | Language |
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dc.date.accessioned | 2012-11-30T08:39:11Z | - |
dc.date.available | 2012-11-30T08:39:11Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | WO Published patent application WO 2008049330. World Intellectual Property Organization (WIPO), PatentScope, 2008 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/177123 | - |
dc.description.abstract | Methods and compositions for identifying and treating obesity and obesity induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in mammalian subjects. The method includes measuring the concentration of circulating lipocalin-2 in a subject and comparing the measured level to lipocalin-2 to a reference level. Another aspect provides methods of treating insulin resistance, type 2 diabetes and other related complications by administering to a patient a composition that can reduce the circulating levels of lipocalin-2, for example a lipocalin-2 antagonist. | en_HK |
dc.relation.isreferencedby | WO 2012042061 (A1) 2012-04-05 | en_HK |
dc.relation.isreferencedby | WO 2011156715 (A2) 2011-12-15 | en_HK |
dc.relation.isreferencedby | WO 2011156715 (A3) 2012-05-10 | en_HK |
dc.relation.isreferencedby | WO 2010132479 (A3) 2011-03-31 | en_HK |
dc.relation.isreferencedby | WO 2010132479 (A2) 2010-11-18 | en_HK |
dc.title | USE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET | en_HK |
dc.type | Patent | en_US |
dc.description.nature | published_or_final_version | en_US |
dc.contributor.inventor | Xu, A | en_HK |
dc.contributor.inventor | Wang, Y | en_HK |
dc.contributor.inventor | Lam, KSL | en_HK |
patents.identifier.application | PC T/CN2007003005 | en_HK |
patents.description.assignee | UNIV HONG KONG [CN]; XU AIMIN [CN]; WANG YU [CN]; LAM SIULING KAREN [CN] | en_HK |
patents.description.country | World Intellectual Property Organization (WIPO) | en_HK |
patents.date.publication | 2008-05-02 | en_HK |
dc.relation.references | US 2004132984 (A1) 2004-07-08 | en_HK |
dc.relation.references | CN 1040323 (C) 1998-10-21 | en_HK |
dc.relation.references | CN 1101911 (A) 1995-04-26 | en_HK |
dc.relation.references | CN 1302206 (A) 2001-07-04 | en_HK |
dc.relation.references | US 5702902 (A) 1997-12-30 | en_HK |
dc.relation.references | US 2004002112 (A1) 2004-01-01 | en_HK |
patents.date.application | 2007-10-22 | en_HK |
patents.date.priority | 2006-10-20 US 11/853404P | en_HK |
patents.description.cc | WO | en_HK |
patents.identifier.publication | WO 2008049330 | en_HK |
patents.relation.family | US 2008095782 (A1) 2008-04-24 | en_HK |
patents.relation.family | US 7645616 (B2) 2010-01-12 | en_HK |
patents.relation.family | US 2010310578 (A1) 2010-12-09 | en_HK |
patents.relation.family | WO 2008049330 (A1) 2008-05-02 | en_HK |
patents.description.kind | A1 | en_HK |
patents.type | Patent_published | en_HK |