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- Publisher Website: 10.1021/am302041b
- Scopus: eid_2-s2.0-84871641879
- PMID: 23176019
- WOS: WOS:000313149800066
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Article: Polydopamine-induced tooth remineralization
Title | Polydopamine-induced tooth remineralization |
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Authors | |
Keywords | dentin enamel hydroxyapatite mussel-adhesion polydopamine remineralization |
Issue Date | 2012 |
Publisher | American Chemical Society. |
Citation | ACS Applied Materials and Interfaces, 2012, v. 4 n. 12, p. 6901-6910 How to Cite? |
Abstract | Inspired by mussel bioadhesion in nature, dopamine is extensively used for biomaterial surface modification. In this study, we coated dopamine on demineralized enamel and dentin surfaces to evaluate the effect of polydopamine coating on dental remineralization. Dental slices containing enamel and dentin were first etched with 37% phosphoric acid for 2 min, followed by immersion in a 2 mg/mL freshly prepared solution of dopamine (10 mM Tris buffer, pH 8.5) for approximately 24 h at room temperature in the dark to obtain polydopamine coating. Then, the dental slices with and without polydopamine coating were immersed in the supersaturated solution of calcium and phosphate at 37 °C for 2 and 7 days. The supersaturated solution of calcium and phosphate was refreshed each day. The precipitates were characterized by SEM, XRD, FTIR, microhardness, and nanoscratch analyses. No significant difference was observed in the remineralization of enamel whether it was coated with polydopamine or not. However, a significant difference was found in dentin remineralization between dentin with and without polydopamine coating. Polydopamine coating remarkably promoted demineralized dentin remineralization, and all dentin tubules were occluded by densely packed hydroxyapatite crystals. Thus, coating polydopamine on dental tissue surface may be a simple universal technique to induce enamel and dentin remineralization simultaneously. |
Persistent Identifier | http://hdl.handle.net/10722/181041 |
ISSN | 2023 Impact Factor: 8.3 2023 SCImago Journal Rankings: 2.058 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Zhou, YZ | - |
dc.contributor.author | Cao, Y | - |
dc.contributor.author | Liu, W | - |
dc.contributor.author | Chu, CH | - |
dc.contributor.author | Li, QL | - |
dc.date.accessioned | 2013-02-19T11:31:08Z | - |
dc.date.available | 2013-02-19T11:31:08Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | ACS Applied Materials and Interfaces, 2012, v. 4 n. 12, p. 6901-6910 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | http://hdl.handle.net/10722/181041 | - |
dc.description.abstract | Inspired by mussel bioadhesion in nature, dopamine is extensively used for biomaterial surface modification. In this study, we coated dopamine on demineralized enamel and dentin surfaces to evaluate the effect of polydopamine coating on dental remineralization. Dental slices containing enamel and dentin were first etched with 37% phosphoric acid for 2 min, followed by immersion in a 2 mg/mL freshly prepared solution of dopamine (10 mM Tris buffer, pH 8.5) for approximately 24 h at room temperature in the dark to obtain polydopamine coating. Then, the dental slices with and without polydopamine coating were immersed in the supersaturated solution of calcium and phosphate at 37 °C for 2 and 7 days. The supersaturated solution of calcium and phosphate was refreshed each day. The precipitates were characterized by SEM, XRD, FTIR, microhardness, and nanoscratch analyses. No significant difference was observed in the remineralization of enamel whether it was coated with polydopamine or not. However, a significant difference was found in dentin remineralization between dentin with and without polydopamine coating. Polydopamine coating remarkably promoted demineralized dentin remineralization, and all dentin tubules were occluded by densely packed hydroxyapatite crystals. Thus, coating polydopamine on dental tissue surface may be a simple universal technique to induce enamel and dentin remineralization simultaneously. | - |
dc.language | eng | - |
dc.publisher | American Chemical Society. | - |
dc.relation.ispartof | ACS Applied Materials and Interfaces | - |
dc.subject | dentin | - |
dc.subject | enamel | - |
dc.subject | hydroxyapatite | - |
dc.subject | mussel-adhesion | - |
dc.subject | polydopamine | - |
dc.subject | remineralization | - |
dc.title | Polydopamine-induced tooth remineralization | - |
dc.type | Article | - |
dc.identifier.email | Chu, CH: chchu@hku.hk | - |
dc.identifier.authority | Chu, CH=rp00022 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1021/am302041b | - |
dc.identifier.pmid | 23176019 | - |
dc.identifier.scopus | eid_2-s2.0-84871641879 | - |
dc.identifier.hkuros | 213361 | - |
dc.identifier.volume | 4 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 6901 | - |
dc.identifier.epage | 6910 | - |
dc.identifier.eissn | 1944-8252 | - |
dc.identifier.isi | WOS:000313149800066 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1944-8244 | - |