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- Publisher Website: 10.1097/SMJ.0b013e3181bfd420
- Scopus: eid_2-s2.0-73949094364
- PMID: 20016431
- WOS: WOS:000272635100013
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Article: Surgical margins in breast conservation therapy: How much should we excise?
Title | Surgical margins in breast conservation therapy: How much should we excise? |
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Authors | |
Keywords | Breast conservation therapy Local recurrence Surgical margin |
Issue Date | 2009 |
Publisher | Lippincott Williams & Wilkins. |
Citation | Southern Medical Journal, 2009, v. 102 n. 12, p. 1234-1237 How to Cite? |
Abstract | BACKGROUND:: Breast conservation therapy (BCT) has become the standard of treatment for early stage breast cancer, and the surgical margin was one of the important factors that affected risk of local recurrence. This review looks at the safe margin for BCT in early stage invasive breast cancer and ductal carcinoma in situ (DCIS). METHODS:: Published literature abstracted in Medline was searched using the gateway site from the US National Library of Medicine. CONCLUSIONS:: A positive margin is associated with increased risk of local recurrence after BCT for invasive breast cancer and DCIS. However there was no cut off for the margin width and the significance of a close margin remains controversial. It was generally accepted that the risk of local recurrence was low if the margin was ≥10 mm while margins that were <2 mm were considered inadequate. The surgeon needs to balance the risk between local recurrence and cosmesis in planning BCT so that the prognosis is not compromised. Copyright © 2009 by The Southern Medical Association. |
Persistent Identifier | http://hdl.handle.net/10722/182314 |
ISSN | 2023 Impact Factor: 1.0 2023 SCImago Journal Rankings: 0.357 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Law, TT | en_HK |
dc.contributor.author | Kwong, A | en_HK |
dc.date.accessioned | 2013-04-22T01:39:25Z | - |
dc.date.available | 2013-04-22T01:39:25Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | Southern Medical Journal, 2009, v. 102 n. 12, p. 1234-1237 | en_HK |
dc.identifier.issn | 0038-4348 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/182314 | - |
dc.description.abstract | BACKGROUND:: Breast conservation therapy (BCT) has become the standard of treatment for early stage breast cancer, and the surgical margin was one of the important factors that affected risk of local recurrence. This review looks at the safe margin for BCT in early stage invasive breast cancer and ductal carcinoma in situ (DCIS). METHODS:: Published literature abstracted in Medline was searched using the gateway site from the US National Library of Medicine. CONCLUSIONS:: A positive margin is associated with increased risk of local recurrence after BCT for invasive breast cancer and DCIS. However there was no cut off for the margin width and the significance of a close margin remains controversial. It was generally accepted that the risk of local recurrence was low if the margin was ≥10 mm while margins that were <2 mm were considered inadequate. The surgeon needs to balance the risk between local recurrence and cosmesis in planning BCT so that the prognosis is not compromised. Copyright © 2009 by The Southern Medical Association. | en_HK |
dc.language | eng | - |
dc.publisher | Lippincott Williams & Wilkins. | - |
dc.relation.ispartof | Southern Medical Journal | en_HK |
dc.rights | This is a non-final version of an article published in final form in (provide complete journal citation) | - |
dc.subject | Breast conservation therapy | en_HK |
dc.subject | Local recurrence | en_HK |
dc.subject | Surgical margin | en_HK |
dc.subject.mesh | Breast Neoplasms - pathology - surgery | - |
dc.subject.mesh | Carcinoma, Intraductal, Noninfiltrating - pathology - surgery | - |
dc.subject.mesh | Mastectomy, Segmental - methods | - |
dc.subject.mesh | Neoplasm Recurrence, Local - prevention and control | - |
dc.subject.mesh | Prognosis | - |
dc.title | Surgical margins in breast conservation therapy: How much should we excise? | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Kwong, A: avakwong@hkucc.hku.hk | en_HK |
dc.identifier.authority | Kwong, A=rp01734 | en_HK |
dc.identifier.doi | 10.1097/SMJ.0b013e3181bfd420 | en_HK |
dc.identifier.pmid | 20016431 | - |
dc.identifier.scopus | eid_2-s2.0-73949094364 | en_HK |
dc.identifier.hkuros | 172701 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-73949094364&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 102 | en_HK |
dc.identifier.issue | 12 | en_HK |
dc.identifier.spage | 1234 | en_HK |
dc.identifier.epage | 1237 | en_HK |
dc.identifier.isi | WOS:000272635100013 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Law, TT=27368145000 | en_HK |
dc.identifier.scopusauthorid | Kwong, A=8913654300 | en_HK |
dc.identifier.issnl | 0038-4348 | - |