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Article: Esophageal squamous cell carcinoma (ESCC): advance in genomics and molecular genetics

TitleEsophageal squamous cell carcinoma (ESCC): advance in genomics and molecular genetics
Authors
Chen, JKwong, DLWCao, THu, QZhang, LMing, XChen, JFu, LGuan, X
KeywordsMicroRNA
esophageal cancer
proteomics
transcriptomics
Issue Date2015
PublisherOxford University Press. The Journal's web site is located at https://academic.oup.com/dote
Citation
Diseases of the Esophagus, 2015, v. 28 n. 1, p. 84-89 How to Cite?
DOI: http://dx.doi.org/10.1111/dote.12088
AbstractEsophageal cancer is aggressive and has poor prognosis. Esophageal squamous cell carcinoma (ESCC) is histologically the most prevalent type of esophageal cancer and ranked as the sixth leading cause of cancer death worldwide. In recent years, cancer has been widely regarded as genetic disease, as well as epigenetic abnormalities including DNA methylation, histone deacetylation, chromatin remodeling, gene imprinting and noncoding RNA regulation. In this review, we will provide a general overview of genes, proteins and microRNAs that are involved in the development of ESCC, which aims to enhance our understanding of molecular mechanisms implicated in ESCC development and progression.
Persistent Identifierhttp://hdl.handle.net/10722/188991
ISSN
1442-2050
2021 Impact Factor: 2.822
2020 SCImago Journal Rankings: 1.115
ISI Accession Number ID
WOS:000350472000010

 

DC FieldValueLanguage
dc.contributor.authorChen, J-
dc.contributor.authorKwong, DLW-
dc.contributor.authorCao, T-
dc.contributor.authorHu, Q-
dc.contributor.authorZhang, L-
dc.contributor.authorMing, X-
dc.contributor.authorChen, J-
dc.contributor.authorFu, L-
dc.contributor.authorGuan, X-
dc.date.accessioned2013-09-17T14:22:41Z-
dc.date.available2013-09-17T14:22:41Z-
dc.date.issued2015-
dc.identifier.citationDiseases of the Esophagus, 2015, v. 28 n. 1, p. 84-89-
dc.identifier.issn1442-2050-
dc.identifier.urihttp://hdl.handle.net/10722/188991-
dc.description.abstractEsophageal cancer is aggressive and has poor prognosis. Esophageal squamous cell carcinoma (ESCC) is histologically the most prevalent type of esophageal cancer and ranked as the sixth leading cause of cancer death worldwide. In recent years, cancer has been widely regarded as genetic disease, as well as epigenetic abnormalities including DNA methylation, histone deacetylation, chromatin remodeling, gene imprinting and noncoding RNA regulation. In this review, we will provide a general overview of genes, proteins and microRNAs that are involved in the development of ESCC, which aims to enhance our understanding of molecular mechanisms implicated in ESCC development and progression.-
dc.languageeng-
dc.publisherOxford University Press. The Journal's web site is located at https://academic.oup.com/dote-
dc.relation.ispartofDiseases of the Esophagus-
dc.subjectMicroRNA-
dc.subjectesophageal cancer-
dc.subjectproteomics-
dc.subjecttranscriptomics-
dc.titleEsophageal squamous cell carcinoma (ESCC): advance in genomics and molecular genetics-
dc.typeArticle-
dc.identifier.emailKwong, DLW: dlwkwong@hku.hk-
dc.identifier.emailFu, L: gracefu@graduate.hku.hk-
dc.identifier.emailGuan, X: xyguan@hkucc.hku.hk-
dc.identifier.authorityKwong, DLW=rp00414-
dc.identifier.authorityFu, L=rp01435-
dc.identifier.authorityGuan, X=rp00454-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/dote.12088-
dc.identifier.pmid23796192-
dc.identifier.scopuseid_2-s2.0-84921604867-
dc.identifier.hkuros224688-
dc.identifier.volume28-
dc.identifier.issue1-
dc.identifier.spage84-
dc.identifier.epage89-
dc.identifier.isiWOS:000350472000010-
dc.publisher.placeUnited States-

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