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Conference Paper: A surface diffusion method for cortical Mn administration in MEMRI

TitleA surface diffusion method for cortical Mn administration in MEMRI
Authors
Han, AWFan, SJWu, EX
Issue Date2013
PublisherISMRM.
Citation
The 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 1255 How to Cite?
AbstractManganese enhanced MRI (MEMRI) is effective for studying brain activity, tracing neuronal pathways and layer-specific cortical microstructures , but the invasiveness of Mn administration methods may cause neuropathological changes, contaminating in vivo MEMRI investigation of neural functions. This study demonstrated a surface diffusion method as a less invasive alternative with similar signal intensity enhancement efficiency to the intracortical injection methods previously employed in MEMRI. Besides reducing disturbance to the physiology of the injection site, this method also allows large dosage application for tracing long-distance connections, e.g. corticospinal pathway. One application is studying brain connectivity and its functional modulation. (Abstract by ISMRM)
DescriptionTraditional Poster Session: Neuro B - Manganese Enhanced MRI
ISMRM Merit Award: Magna cum Laude
Persistent Identifierhttp://hdl.handle.net/10722/191640
ISSN
1557-3672

 

DC FieldValueLanguage
dc.contributor.authorHan, AWen_US
dc.contributor.authorFan, SJen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2013-10-15T07:14:49Z-
dc.date.available2013-10-15T07:14:49Z-
dc.date.issued2013en_US
dc.identifier.citationThe 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 1255en_US
dc.identifier.issn1557-3672-
dc.identifier.urihttp://hdl.handle.net/10722/191640-
dc.descriptionTraditional Poster Session: Neuro B - Manganese Enhanced MRI-
dc.descriptionISMRM Merit Award: Magna cum Laude-
dc.description.abstractManganese enhanced MRI (MEMRI) is effective for studying brain activity, tracing neuronal pathways and layer-specific cortical microstructures , but the invasiveness of Mn administration methods may cause neuropathological changes, contaminating in vivo MEMRI investigation of neural functions. This study demonstrated a surface diffusion method as a less invasive alternative with similar signal intensity enhancement efficiency to the intracortical injection methods previously employed in MEMRI. Besides reducing disturbance to the physiology of the injection site, this method also allows large dosage application for tracing long-distance connections, e.g. corticospinal pathway. One application is studying brain connectivity and its functional modulation. (Abstract by ISMRM)-
dc.languageengen_US
dc.publisherISMRM.-
dc.relation.ispartofSociety of Magnetic Resonance in Medicine Proceedingsen_US
dc.titleA surface diffusion method for cortical Mn administration in MEMRIen_US
dc.typeConference_Paperen_US
dc.identifier.emailWu, EX: ewu1@hkucc.hku.hken_US
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros226009en_US
dc.identifier.volume21-
dc.identifier.spage1255en_US
dc.identifier.epage1255en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.issnl1065-9889-

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