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Conference Paper: Hypoxia decreases resting-state functional connectivity in anesthetized rats

TitleHypoxia decreases resting-state functional connectivity in anesthetized rats
Authors
Cheng, JSZhou, IYGao, PPChan, RWWu, EX
Issue Date2013
PublisherInternational Society for Magnetic Resonance in Medicine (ISMRM).
Citation
The 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 3312 How to Cite?
AbstractResting-state functional MRI (rsfMRI) utilizing blood-oxygen-level-dependent (BOLD) contrast has increasingly used to map inter and intra-hemispheric connectivity in normal and diseased brains. However BOLD is a complex function of changes in oxygen metabolism, cerebral blood flow (CBF), and cerebral blood volume (CBV). While the effect of various gas inspirations including hypoxia on baseline and stimulus-evoked BOLD signal have been documented, how BOLD synchronization or rsfMRI can be affected by hypoxia has not been investigated. This study aims to assess the effect of graded hypoxia on BOLD rsfMRI connectivity in an animal model and shows that both mild and severe hypoxia suppressed BOLD rsfMRI connectivity significantly. (Abstract by ISMRM)
DescriptionElectronic Poster Session: Functional MRI (neuro) - Resting State Connectivity: Applications
Persistent Identifierhttp://hdl.handle.net/10722/191647
ISSN
1557-3672

 

DC FieldValueLanguage
dc.contributor.authorCheng, JSen_US
dc.contributor.authorZhou, IYen_US
dc.contributor.authorGao, PPen_US
dc.contributor.authorChan, RWen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2013-10-15T07:14:51Z-
dc.date.available2013-10-15T07:14:51Z-
dc.date.issued2013en_US
dc.identifier.citationThe 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 3312en_US
dc.identifier.issn1557-3672-
dc.identifier.urihttp://hdl.handle.net/10722/191647-
dc.descriptionElectronic Poster Session: Functional MRI (neuro) - Resting State Connectivity: Applications-
dc.description.abstractResting-state functional MRI (rsfMRI) utilizing blood-oxygen-level-dependent (BOLD) contrast has increasingly used to map inter and intra-hemispheric connectivity in normal and diseased brains. However BOLD is a complex function of changes in oxygen metabolism, cerebral blood flow (CBF), and cerebral blood volume (CBV). While the effect of various gas inspirations including hypoxia on baseline and stimulus-evoked BOLD signal have been documented, how BOLD synchronization or rsfMRI can be affected by hypoxia has not been investigated. This study aims to assess the effect of graded hypoxia on BOLD rsfMRI connectivity in an animal model and shows that both mild and severe hypoxia suppressed BOLD rsfMRI connectivity significantly. (Abstract by ISMRM)-
dc.languageengen_US
dc.publisherInternational Society for Magnetic Resonance in Medicine (ISMRM).-
dc.relation.ispartofSociety of Magnetic Resonance in Medicine Proceedingsen_US
dc.titleHypoxia decreases resting-state functional connectivity in anesthetized ratsen_US
dc.typeConference_Paperen_US
dc.identifier.emailZhou, IY: iriszhou@eee.hku.hken_US
dc.identifier.emailWu, EX: ewu1@hkucc.hku.hken_US
dc.identifier.authorityZhou, IY=rp01739en_US
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros226033en_US
dc.identifier.volume21-
dc.identifier.spage3312en_US
dc.identifier.epage3312en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.issnl1065-9889-

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