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Conference Paper: Maximum likelihood estimation of blood velocity using Doppler optical coherence tomography
Title | Maximum likelihood estimation of blood velocity using Doppler optical coherence tomography |
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Authors | |
Keywords | Decorrelation Doppler optical coherence tomography Maximum likelihood estimation |
Issue Date | 2014 |
Publisher | S P I E - International Society for Optical Engineering. The Journal's web site is located at http://spie.org/x1848.xml?WT.svl=mddp2 |
Citation | Conference 8934 - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, San Francisco, United States, 3 -5 February 2014. In Proceedings of SPIE, 2014, v. 8934, p. article no. 89342J How to Cite? |
Abstract | A recent trend in optical coherence tomography (OCT) hardware has been the move towards higher A-scan rates. However, the estimation of axial blood flow velocities is affected by the presence and type of noise, as well as the estimation method. Higher acquisition rates alone do not enable the accurate quantification of axial blood velocity. Moreover, decorrelation is an unavoidable feature of OCT signals when there is motion relative to the OCT beam. For in-vivo OCT measurements of blood flow, decorrelation noise affects Doppler frequency estimation by broadening the signal spectrum. Here we derive a maximum likelihood estimator (MLE) for Doppler frequency estimation that takes into account spectral broadening due to decorrelation. We compare this estimator with existing techniques. Both theory and experiment show that this estimator is effective, and outperforms the Kasai and additive white Gaussian noise (AWGN) ML estimators. We find that maximum likelihood estimation can be useful for estimating Doppler shifts for slow axial flow and near transverse flow. Due to the inherent linear relationship between decorrelation and Doppler shift of scatterers moving relative to an OCT beam, decorrelation itself may be a measure of flow speed. |
Persistent Identifier | http://hdl.handle.net/10722/201230 |
ISBN | |
ISSN | 2023 SCImago Journal Rankings: 0.152 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, CWA | en_US |
dc.contributor.author | Merkle, C | en_US |
dc.contributor.author | Lam, EYM | en_US |
dc.contributor.author | Srinivasan, V | en_US |
dc.date.accessioned | 2014-08-21T07:18:17Z | - |
dc.date.available | 2014-08-21T07:18:17Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Conference 8934 - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, San Francisco, United States, 3 -5 February 2014. In Proceedings of SPIE, 2014, v. 8934, p. article no. 89342J | en_US |
dc.identifier.isbn | 9780819498472 | - |
dc.identifier.issn | 0277-786X | - |
dc.identifier.uri | http://hdl.handle.net/10722/201230 | - |
dc.description.abstract | A recent trend in optical coherence tomography (OCT) hardware has been the move towards higher A-scan rates. However, the estimation of axial blood flow velocities is affected by the presence and type of noise, as well as the estimation method. Higher acquisition rates alone do not enable the accurate quantification of axial blood velocity. Moreover, decorrelation is an unavoidable feature of OCT signals when there is motion relative to the OCT beam. For in-vivo OCT measurements of blood flow, decorrelation noise affects Doppler frequency estimation by broadening the signal spectrum. Here we derive a maximum likelihood estimator (MLE) for Doppler frequency estimation that takes into account spectral broadening due to decorrelation. We compare this estimator with existing techniques. Both theory and experiment show that this estimator is effective, and outperforms the Kasai and additive white Gaussian noise (AWGN) ML estimators. We find that maximum likelihood estimation can be useful for estimating Doppler shifts for slow axial flow and near transverse flow. Due to the inherent linear relationship between decorrelation and Doppler shift of scatterers moving relative to an OCT beam, decorrelation itself may be a measure of flow speed. | - |
dc.language | eng | en_US |
dc.publisher | S P I E - International Society for Optical Engineering. The Journal's web site is located at http://spie.org/x1848.xml?WT.svl=mddp2 | - |
dc.relation.ispartof | Proceedings of SPIE - International Society for Optical Engineering | en_US |
dc.rights | Copyright 2014 Society of Photo‑Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this publication for a fee or for commercial purposes, and modification of the contents of the publication are prohibited. This article is available online at https://doi.org/10.1117/12.2036491 | - |
dc.subject | Decorrelation | - |
dc.subject | Doppler optical coherence tomography | - |
dc.subject | Maximum likelihood estimation | - |
dc.title | Maximum likelihood estimation of blood velocity using Doppler optical coherence tomography | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Lam, EYM: elam@eee.hku.hk | en_US |
dc.identifier.authority | Lam, EYM=rp00131 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1117/12.2036491 | - |
dc.identifier.scopus | eid_2-s2.0-84896941607 | - |
dc.identifier.hkuros | 233701 | en_US |
dc.identifier.volume | 8934 | - |
dc.identifier.spage | article no. 89342J | - |
dc.identifier.epage | article no. 89342J | - |
dc.identifier.isi | WOS:000336744800022 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 0277-786X | - |